Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!



A 2-year integrated agriculture and nutrition and health behavior change communication program targeted to women in Burkina Faso reduces anemia, wasting, and diarrhea in children 3-12.9 months of age at baseline: a cluster-randomized controlled trial

Olney, D. K., Pedehombga, A., Ruel, M. T., Dillon, A.. "A 2-year integrated agriculture and nutrition and health behavior change communication program targeted to women in Burkina Faso reduces anemia, wasting, and diarrhea in children 3-12.9 months of age at baseline: a cluster-randomized controlled trial." The Journal of Nutrition 145 , no. 6 (2015) : 1317-1324
Study Interventions
  • Behavior change communication (BCC)
Research Gaps
  • Innovation
Countries
  • Burkina Faso
Nutritional Problems
  • Stunted
  • MAM

A cluster RCT to measure the effectiveness and of cash-based interventions on nutrition status, Sindh Province, Pakistan

Fenn, B.. "A cluster RCT to measure the effectiveness and of cash-based interventions on nutrition status, Sindh Province, Pakistan." ENN Field Exchange 42 (2017) : 61
Study Interventions
  • Cash transfer
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Pakistan
Nutritional Problems
  • Stunted
  • MAM

A cluster-randomized trial determining the efficacy of caterpillar cereal as a locally available and sustainable complementary food to prevent stunting and anaemia

Bauserman, M., Lokangaka, A., Gado, J., Close, K., Wallace, D., Kodondi, K., Tshefu, A., Bose, C.. "A cluster-randomized trial determining the efficacy of caterpillar cereal as a locally available and sustainable complementary food to prevent stunting and anaemia." Public Health Nutrition 18 , no. 10 (2015) : 1785-92
Study Interventions
  • Locally produced
Research Gaps
  • Innovation
Countries
  • Democratic Republic of the Congo
Nutritional Problems
  • Stunted

A combined intervention of zinc, multiple micronutrients, and Albendazole does not ameliorate environmental enteric dysfunction or stunting in rural Malawian children in a double-blind randomized controlled trial

Wang, A. Z., Shulman, R. J., Crocker, A. H., Thakwalakwa, C., Maleta, K. M., Devaraj, S., Manary, M., Trehan, I.. "A combined intervention of zinc, multiple micronutrients, and Albendazole does not ameliorate environmental enteric dysfunction or stunting in rural Malawian children in a double-blind randomized controlled trial." The Journal of Nutrition 147 , no. 1 (2017) : 97-103
Study Interventions
  • Micronutrient products (MNP)
Research Gaps
  • Composition
  • Effectiveness
Countries
  • Malawi
Nutritional Problems
  • Stunted

A comprehensive linear programming tool to optimize formulations of ready-to-use therapeutic foods: an application to Ethiopia

Ryan, K. N., Adams, K. P., Vosti, S. A., Ordiz, M. I., Cimo, E. D., Manary, M. J.. "A comprehensive linear programming tool to optimize formulations of ready-to-use therapeutic foods: an application to Ethiopia." The American Journal of Clinical Nutrition 100 , no. 6 (2014) : 1551-1558
Study Interventions
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Countries
  • Ethiopia
Nutritional Problems
  • SAM

A food transfer program without a formal education component modifies complementary feeding practices in poor rural Mexican communities

Ramírez-Luzuriaga, M. J., Unar-Munguía, M., Rodríguez-Ramírez, S., Rivera, J. A., González de Cosío, T.. "A food transfer program without a formal education component modifies complementary feeding practices in poor rural Mexican communities." The Journal of Nutrition 146 , no. 1 (2016) : 107-13
Study Interventions
  • Animal-source protein
  • Behavior change communication (BCC)
  • Cash transfer
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Mexico
Nutritional Problems
  • Stunted

A lipid-based nutrient supplement but not corn-soy blend modestly increases weight gain among 6-to 18-month-old moderately underweight children in rural Malawi

Thakwalakwa, C., Ashorn, P., Phuka, J., Cheung, Y. B., Briend, A., Puumalainen, T., Maleta, K.. "A lipid-based nutrient supplement but not corn-soy blend modestly increases weight gain among 6-to 18-month-old moderately underweight children in rural Malawi." The Journal of Nutrition 140 , no. 11 (2010) : 2008-2013
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Countries
  • Malawi
Nutritional Problems
  • MAM

A mixed method study exploring adherence to and acceptability of small quantity lipid-based nutrient supplements (SQ-LNS) among pregnant and lactating women in Ghana and Malawi

Klevor, M. K., Adu-Afarwuah, S., Ashorn, P., Arimond, M., Dewey, K. G., Lartey, A., Maleta, K., Phiri, N., Pyykko, J., Zeilani, M., Ashorn, U.. "A mixed method study exploring adherence to and acceptability of small quantity lipid-based nutrient supplements (SQ-LNS) among pregnant and lactating women in Ghana and Malawi." BMC Pregnancy and Childbirth 16 , no. 1 (2016) : 253
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Acceptability
  • Use
Countries
  • Malawi
  • Ghana
Nutritional Problems
  • Stunted
  • Pregnant & Lactating Women

A novel fortified blended flour, corn-soy blend "plus-plus," is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children

LaGrone, L. N., Trehan, I., Meuli, G. J., Wang, R. J., Thakwalakwa, C., Maleta, K., Manary, M. J.. "A novel fortified blended flour, corn-soy blend "plus-plus," is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children." The American Journal of Clinical Nutrition 95 , no. 1 (2012) : 212-9
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Countries
  • Malawi
Nutritional Problems
  • MAM

A randomized controlled facility based trial to assess the impact of indigenously prepared ready to use therapeutic food (RUTF) for children with severe acute malnutrition in India

Jadhav, A., Dias, B., Shah, N., Fernandes, L., Fernandes, S., Surve, A., Dhami-Shah, H., Murty, S., Joshi, N., Manglani, M.. "A randomized controlled facility based trial to assess the impact of indigenously prepared ready to use therapeutic food (RUTF) for children with severe acute malnutrition in India." Pediatric Oncall Journal 13 , no. 4 (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Countries
  • India
Nutritional Problems
  • SAM

A randomized controlled trial offering higher- compared with lower-dairy second meals daily in preschools in Guinea-Bissau demonstrates an attendance-dependent increase in weight gain for both meal types and an increase in mid-upper arm circumference

Batra, P., Schlossman, N., Balan, I., Pruzensky, W., Balan, A., Brown, C., Gamache, M. G., Schleicher, M. M., Braima de Sa, A., Saltzman, E., Wood, L., Roberts, S. B.. "A randomized controlled trial offering higher- compared with lower-dairy second meals daily in preschools in Guinea-Bissau demonstrates an attendance-dependent increase in weight gain for both meal types and an increase in mid-upper arm circumference." The Journal of Nutrition 146 , no. 1 (2015) : 124-132
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
  • Use
Countries
  • Guinea-Bissau
Nutritional Problems
  • Stunted
  • MAM

A ready-to-use therapeutic food containing 10% milk is less effective than one with 25% milk in the treatment of severely malnourished children

Oakley, E., Reinking, J., Sandige, H., Trehan, I., Kennedy, G., Maleta, K., Manary, M.. "A ready-to-use therapeutic food containing 10% milk is less effective than one with 25% milk in the treatment of severely malnourished children." The Journal of Nutrition 140 , no. 12 (2010) : 2248-2252
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Efficacy
Countries
  • Malawi
Nutritional Problems
  • SAM

A single-centre, randomized, single-blind, parallel group clinical trial in rural Malawi, testing the growth promoting effect of long-term complementary feeding of infants with a high-energy, micronutrient fortified spread

Mangani, C., Manary, M., Alho, L., Ashorn, P.. "A single-centre, randomized, single-blind, parallel group clinical trial in rural Malawi, testing the growth promoting effect of long-term complementary feeding of infants with a high-energy, micronutrient fortified spread." FANTA Project (2012)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Countries
  • Malawi
Nutritional Problems
  • Stunted
  • MAM

A tale of two measures: Self-report and lab-assessed values in amount of oil Added to CSB porridge prepared by caregivers of children with moderate acute malnutrition in Southern Malawi

Langlois, B., Rogers, B.. "A tale of two measures: Self-report and lab-assessed values in amount of oil Added to CSB porridge prepared by caregivers of children with moderate acute malnutrition in Southern Malawi." The FASEB Journal 30 , no. 1 (2016)
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
Research Gaps
  • Use
Countries
  • Malawi
Nutritional Problems
  • MAM

Acceptability and efficacy of locally produced ready-to-use therapeutic food nutreal in the management of severe acute malnutrition in comparison with defined food: A randomized control trial

Thapa, B. R., Goyal, P., Menon, J., Sharma, A.. "Acceptability and efficacy of locally produced ready-to-use therapeutic food nutreal in the management of severe acute malnutrition in comparison with defined food: A randomized control trial." Food and Nutrition Bulletin 38 , no. 1 (2017) : 18-26
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Effectiveness
  • Innovation
Countries
  • India
Nutritional Problems
  • SAM