Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 29 Results
Khan, A. I. , Kabir, I., Hawkesworth, S., Ekström, E., Arifeen, S., Frongillo, E. A., Persson, L. A.. "Early invitation to food and/or multiple micronutrient supplementation in pregnancy does not affect body composition in offspring at 54 months: follow-up of the MINIMat randomised trial, Bangladesh ." Maternal & Child Nutrition 11 , no. 3 (2013) : 385-397
Study Interventions
  • Micronutrient powders (MNP)
  • Other
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
  • GAM
Christian, P., Shaikh, S., Shamim, A. A., Mehra, S., Wu, L., Merrill, R. D., Klemm, R., Schulze, K., Pee, S., Ahmed, T.. "Effect of fortified complementary food supplementation on child growth in rural Bangladesh: A cluster-randomized trial ." The FASEB Journal 29 , no. 1 Supplement (2015) : 120.5
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Grellety, E., Shepherd, S., Roederer, T., Manzo, M. L., Doyon, S., Ategbo, E., Grais, R. F.. "Effect of mass supplementation with ready-to-use supplementary food during an anticipated nutritional emergency ." PloS One 7 , no. 9 (2012) : e44549
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted
  • GAM
Isanaka, S., Nombela, N.ohelly, Djibo, A., Poupard, M., Van Beckhoven, D., Gaboulaud, V., Guerin, P. J., Grais, R. F.. "Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial. ." Journal of the American Medical Association 301 , no. 3 (2009) : 277-85
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • GAM
van der Kam, S., Roll, S., Salse, N., Jiya, N. M., Swarthout, T. D., Matsumoto, A., Toyoshima, S., Shanks, L.. "Effectiveness of nutritional supplementation (RUTF and multi micronutrient) in preventing malnutrition and morbidity in children 6-59 months with infection ." MSF Field Research (2014)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Acceptability
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • GAM
McNulty, Judiann, Harvey, Ruth, Tilford, Kathy. "Impact study report: Comparison of PM2A and MCHN approaches in SOUHARDO II ." (2015)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM
Cohuet, S., Marquer, C., Shepherd, S., Captier, V., Langendorf, C., Ale, F., Phelan, K., Manzo, M. L., Grais, R. F.. "Intra-household use and acceptability of Ready-to-Use-Supplementary-Foods distributed in Niger between July and December 2010 ." Appetite 59 , no. 3 (2012) : 698-705
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • GAM
Bisimwa, G., Owino, V. O., Bahwere, P., Dramaix, M., Donnen, P., Dibari, F., Collins, S.. "Randomized controlled trial of the effectiveness of a soybean-maize-sorghum-based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo ." American Journal of Clinical Nutrition 95 , no. 5 (2012) : 1157-1164
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • GAM
  • Stunted
Maust, A., Koroma, A. S., Abla, C., Molokwu, N., Ryan, K. N., Singh, L., Manary, M. J.. "Severe and moderate acute malnutrition can be successfully managed with an integrated protocol in Sierra Leone ." The Journal of Nutrition 145 , no. 11 (2015) : 2604-2609
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • GAM
Hess, S. Y., Abbeddou, S., Jimenez, E. Y., Somé, J. W., Vosti, Stephen A, Ouédraogo, Z. P., Guissou, R. M., Ouédraogo, J., Brown, K. H.. "Small-quantity lipid-based nutrient supplements, regardless of their zinc content, increase growth and reduce the prevalence of stunting and wasting in young burkinabe children: a cluster-randomized trial ." PloS One 10 , no. 3 (2015) : e0122242
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM
Adu-Afarwuah, S., Lartey, A., Okronipa, H., Ashorn, P., Peerson, J. M., Arimond, M., Ashorn, U., Zeilani, M., Vosti, S., Dewey, K. G.. "Small-quantity, lipid-based nutrient supplements provided to women during pregnancy and 6 mo postpartum and to their infants from 6 mo of age increase the mean attained length of 18-mo-old children in semi-urban Ghana: a randomized controlled trial ." The American Journal of Clinical Nutrition 104 , no. 3 (2016) : 797-808
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Huybregts, L., Houngbé, F., Salpéteur, C., Brown, R., Roberfroid, D., Ait-Aissa, M., Kolsteren, P.. "The effect of adding ready-to-use supplementary food to a general food distribution on child nutritional status and morbidity: a cluster-randomized controlled trial ." PLoS Medicine 9 , no. 9 (2012) : e1001313
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Kampstra, N. A., Van Hoan, N., Koenders, D. J. P. C., Schoop, R., Broersen, C. B., Mouquet-Rivier, C., Traore, T., Bruins, M. J., de Pee, S.. "Energy and nutrient intake increased by 47–67% when amylase was added to fortified blended foods—a study among 12- to 35-month-old Burkinabe children ." Maternal & Child Nutrition (2017)
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Acceptability
  • Composition
Nutritional Problems being Studied
  • Stunted
  • GAM
Adams, A. M., Ahmed, R., Mahbub Latif, A. H. M., Rasheed, S., Das, S. K., Hasib, E., Farzana, F. D., Ferdous, F., Ahmed, S., Faruque, A. S. G.. "Impact of fortified biscuits on micronutrient deficiencies among primary school children in Bangladesh ." PLoS One (2017)
Study Interventions
  • Other
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM
Schlossman, N., Brown, C., Batra, P., Braima de Sa, A., Balan, I., Balan, A., Gamache, M. G., Wood, L., Pruzensky, W., Saltzman, E., Roberts, S. B., Bale, C.. "A randomized controlled trial of two ready-to-use supplementary foods demonstrates benefit of the higher dairy supplement for reduced wasting in mothers, and differential impact in infants and children associated with maternal supplement response ." Food and Nutrition Bulletin 38 , no. 3 (2017) : 275-290
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Pregnant & Lactating Women
  • GAM
Pulungan, A. B., Mirasanti, D. A.. "Effect of community-based food supplementation on improving growth of underweight children under five years of age in West Nusa Tenggara ." Paediatrica Indonesiana 57 , no. 5 (2017) : 246-251
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM
Isanka, S., Roederer, T., Djibo, A., Luquero, F. J., Nombela, N., Guerin, P. J., Grais, R. F.. "Reducing wasting in young children with preventive supplementation: a cohort study in Niger ." Pediatrics 126 , no. 2 (2010)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Lin, C. A., Manary, M. J., Maleta, K., Briend, A., Ashorn, P.. "An energy-dense complementary food is associated with a modest increase in weight gain when compared with a fortified porridge in Malawian children aged 6–18 months ." Journal of Nutrition 138 (2008) : 593-598
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Avula, R., Frongillo, E. A., Arabi, M., Sharma, S., Schultink, W.. "Enhancements to nutrition program in Indian Integrated Child Development Services increased growth and energy intake of children ." The Journal of Nutrition 141 (2011) : 680-684
Study Interventions
  • Locally produced
  • Micronutrient powders (MNP)
  • Other
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
de Pee, S., Moench-Pfanner, R., Martini, E., Zlotkin, S. H., Darnton-Hill, I., Bloem, M. W.. "Home fortification in emergency response and transition programming: Experiences in Aceh and Nias, Indonesia ." Food and Nutrition Bulletin 28 , no. 2 (2007) : 189-197
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM
Hirve, S., Martini, E., Juvekar, S. K., Agarwal, D., Bavdekar, A., Sari, M., Molwane, M., Janes, S., Haselow, N., Yeung, D. L., Pandit, A.. "Delivering Sprinkles Plus through the Integrated Child Development Services (ICDS) to Reduce Anemia in Pre-school Children in India ." The Indian Journal of Pediatrics 80 , no. 12 (2013) : 990-995
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted
  • GAM
Ziauddin Hyder, S. M., Haseen, F., Rahman, M., Tondeur, M. C., Zlotkin, S. H.. "Effect of daily versus once-weekly home fortification with micronutrient Sprinkles on hemoglobin and iron status among young children in rural Bangladesh ." Food and Nutrition Bulletin 28 , no. 7 (2007)
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM
Korenromp, E. L., Adeosun, O., Adegoke, F., Akerele, A., Anger, C., Ohajinwa, C., Hotz, C., Umunna, L., Aminu, F.. "Micronutrient powder distribution through Maternal, Neonatal and Child Health Weeks in Nigeria: process evaluation of feasibility and use ." Public Health Nutrition 19 , no. 10 (2015) : 1882-1892
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient powders (MNP)
Research Gaps
  • Use
Nutritional Problems being Studied
  • Stunted
  • GAM
Kounnavong, S., Sunahara, T., Mascie-Taylor, C. G. N., Hasizume, M., Okumura, J., Moji, K., Boupha, B., Yamamoto, T.. "Effect of daily versus weekly home fortification with multiple micronutrient powder on haemoglobin concentration of young children in a rural area, Lao People’s Democratic Republic: a randomised trial ." Nutrition Journal 10 , no. 129 (2011)
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Leroy, J. L., Sununtnasuk, C., Heckert, J., Olney, D.. "Strengthening and evaluating the Preventing Malnutrition in Children Under 2 Years of Age approach - Burundi follow-up report: Children 24-41 months ." FANTA III: Food and Nutrition Technical Assistance Report (2017)
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM