Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 18 of 18 Results
Oakley, E., Reinking, J., Sandige, H., Trehan, I., Kennedy, G., Maleta, K., Manary, M.. "A ready-to-use therapeutic food containing 10% milk is less effective than one with 25% milk in the treatment of severely malnourished children ." The Journal of Nutrition 140 , no. 12 (2010) : 2248-2252
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Efficacy
Nutritional Problems being Studied
  • SAM
Steenkamp, L., Nomvete, A., Venter, D.. "Catch-up growth in children with severe acute malnutrition: comparison of two therapeutic feeding approaches at a district hospital, South Africa ." Africa Journal of Nursing and Midwifery 17 , no. 2 (2016)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Bahwere, P., Balaluka, B., Wells, J. C., Mbiribindi, C. N., Sadler, K., Akomo, P., Dramaix-Wilmet, M., Collins, S.. "Cereals and pulse-based ready-to-use therapeutic food as an alternative to the standard milk- and peanut paste-based formulation for treating severe acute malnutrition: a noninferiority, individually randomized controlled efficacy clinical trial ." The American Journal of Clinical Nutrition 103 , no. 4 (2016) : 1145-1161
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Efficacy
Nutritional Problems being Studied
  • SAM
Namusoke, H., Hother, A., Rytter, M. J., Kæstel, P., Babirekere-Iriso, E., Fabiansen, C., Girma, T., Ritz, C., Michaelsen, K., Briend, A., Friis, H.. "Changes in plasma phosphate during in-patient treatment of children with severe acute malnutrition: an observational study in Uganda ." The American Journal of Clinical Nutrition (2016)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Babirekere-Iriso, E., Mortensen, C. G., Mupere, E., Rytter, M. J., Namusoke, H., Michaelsen, K. F., Briend, A., Stark, K. D., Friis, H., Lauritzen, L.. "Changes in whole-blood PUFA and their predictors during recovery from severe acute malnutrition ." The British Journal of Nutrition 115 , no. 10 (2016) : 1730-9
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Ige, O. K., Oladokun, R. E., Kikelomo, O.. "Comparative weight gain with ready-to-use therapeutic food in stunted HIV-infected and-uninfected children in a Nigerian Hospital ." South African Journal of Child Health 8 , no. 3 (2014) : 104-107
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Diop, E. H. I., Dossou, N. I., Ndour, M. M., Briend, A., Wade, S.. "Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: A randomized trial ." American Journal of Clinical Nutrition 78 , no. 2 (2003) : 302-307
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Nguefack, F., Adjahoung, C. A., Keugoung, B., Kamgaing, N., Dongmo, R.. "Hospital management of severe acute malnutrition in children with F-75 and F-100 alternative local preparations: results and challenges ." The Pan African Medical Journal 21 (2015) : 329
Study Interventions
  • Animal-source protein
  • Locally produced
Research Gaps
  • Composition
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • SAM
Ningadalli, S. G., Angolkar, M., Herekar, V. R., Hirachand, A. D., Sah, J. K., Madikar, S.. "Impact of facility based dietary management on severe acute malnutrition in children aged 6 to 60 months admitted in nutritional rehabilitation centre of KLES’s Dr. Prabhakar Kore Hospital of Belagavi City - A longitudinal study ." International Journal of Science and Research 4 , no. 5 (2015) : 2133-2137
Study Interventions
  • Not Described
Research Gaps
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • SAM
Zhang, L., Voskuijl, W., Mouzaki, M., Groen, A. K., Alexander, J., Bourdon, C., Wang, A., Versloot, C. J., Di Giovanni, V., Wanders, R. J. A., Bandsma, R. H.. "Impaired bile acid homeostasis in children with severe acute malnutrition ." PLoS ONE 11 , no. 5 (2016) : e0155143
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Caulfield, L. E., Huffman, S. L., Piwoz, E. G.. "Interventions to improve intake of complementary foods by infants 6 to 12 months of age in developing countries: impact on growth and on the prevalence of malnutrition and potential contribution to child survival ." Food and Nutrition Bulletin 2 , no. 2 (1999) : 183-200
Study Interventions
  • Not Described
Research Gaps
  • Effectiveness
  • Efficacy
  • Use
Nutritional Problems being Studied
  • Stunted
  • MAM
Sethuraman, K., Doledec, D., Begum, F., Manir, M. Z.. "Managing acute malnutrition: A review of the evidence and country experiences in South Asia and a recommended approach for Bangladesh ." FANTA Project (2014)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
  • Efficacy
Nutritional Problems being Studied
  • SAM
  • MAM
Shanka, N. A., Lemma, S., Abyu, D. M.. "Recovery rate and determinants in treatment of children with severe acute malnutrition using outpatient therapeutic feeding program in Kamba District, Ethiopia ." Journal of Nutritional Disorders & Therapy 5 , no. 2 (2015)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Thakwalakwa, C. M., Ashorn, P., Phuka, J. C., Cheung, Y. B., Briend, A., Maleta, K. M.. "Impact of lipid-based nutrient supplements and corn-soy blend on energy and nutrient intake among moderately underweight 8-18-month-old children participating in a clinical trial.  ." Maternal & Child Nutrition 11 , no. S4 (2015) : 144-150
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • Stunted
  • MAM
Irena, A., Bahwere, P., Owino, V., Diop, E. I., Bachmann, M., Mbwili-Muleya, C., Dibari, F., Sadler, K., Collins, S.. "Comparison of the effectiveness of a milk-free soy-maize-sorghum-based ready-to-use therapeutic food to standard ready-to-use therapeutic food with 25% milk in nutrition management of severely acutely malnourished Zambian children: an equivalence non-blinded cluster randomised controlled trial ." Maternal & Child Nutrition 11 , no. S4 (2015) : 105-119
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Cost
  • Efficacy
Nutritional Problems being Studied
  • SAM
Rogers, B. L., Wilner, L., Maganga, G., Walton, S., Suri, D. J., Langlois, B., Chui, K. K. H., Boiteau, J., Vosti, S., Webb, P.. "Program changes are effective and cost-effective in increasing the amount of oil used in preparing corn soy blend porridge for treatment of moderate acute malnutrition in Malawi ." Maternal & Child Nutrition (2017)
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Cost
  • Efficacy
  • Use
Nutritional Problems being Studied
  • MAM
Isanka, S., Kodish, S. R., Berthe, F., Alley, I., Nackers, F., Hanson, K. E., Grais, R. F.. "Outpatient treatment of severe acute malnutrition: response to treatment with a reduced schedule of therapeutic food distribution ." The American Journal of Clinical Nutrition (2017)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • SAM
Zeweter Abebe , Gulelat Desse Haki, Kaleab Baye. "." Maternal and Child Nutrition 14 , no. 1 (2017)
Study Interventions
  • Fortified blended foods (FBF)
  • Micronutrient powders (MNP)
  • Other
Research Gaps
  • Efficacy
  • Use
Nutritional Problems being Studied
  • Stunted