Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 26 - 50 of 158 Results
Siega-Riz, A. M., Estrada Del Campo, Y., Kinlaw, A., Reinhart, G. A., Allen, L. H., Shahab-Ferdows, S., Heck, J., Suchindran, C. M., Bentley, M. E.. "Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6-18 months living in the rural region of Intibucá, Honduras ." Paediatric and Perinatal Epidemiology 28 , no. 3 (2014) : 245-254
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Shewade, H. D., Patro, B. K., Bharti, B., Soundappan, K., Kaur, A., Taneja, N.. "Effectiveness of indigenous ready-to-use therapeutic food in community-based management of uncomplicated severe acute malnutrition: a randomized controlled trial from India ." Journal of Tropical Pediatrics 59 , no. 5 (2013) : 393-8
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
Bahwere, P., Banda, T., Sadler, K., Nyirenda, G., Owino, V., Shaba, B., Dibari, F., Collins, S.. "Effectiveness of milk whey protein-based ready-to-use therapeutic food in treatment of severe acute malnutrition in Malawian under-5 children: a randomised, double-blind, controlled non-inferiority clinical trial ." Maternal & Child Nutrition 10 , no. 3 (2014) : 436-451
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • SAM
van der Kam, S., Roll, S., Salse, N., Jiya, N. M., Swarthout, T. D., Matsumoto, A., Toyoshima, S., Shanks, L.. "Effectiveness of nutritional supplementation (RUTF and multi micronutrient) in preventing malnutrition and morbidity in children 6-59 months with infection ." MSF Field Research (2014)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Acceptability
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • GAM
Prado, E. L., Abbeddou, S., Yakes Jimenez, E., Somé, J. W., Dewey, K. G., Brown, K. H., Hess, S. Y.. "Effects of an intervention on infant growth and development: evidence for different mechanisms at work ." Maternal & Child Nutrition (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
Skau, J. K. H., Touch, B., Chhoun, C., Chea, M., Unni, U. S., Makurat, J., Filteau, S., Wieringa, F. T., Dijkhuizen, M. A., Ritz, C., Wells, J. C., Berger, J., Friis, H., Michaelsen, K. F., Roos, N.. "Effects of animal source food and micronutrient fortification in complementary food products on body composition, iron status, and linear growth: A randomized trial in Cambodia ." The American Journal of Clinical Nutrition 101 , no. 4 (2015) : 742-751
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
Hossain, M. I., Nahar, B., Hamadani, J. D., Ahmed, T., Brown, K. H.. "Effects of community-based follow-up care in managing severely underweight children ." Journal of Pediatric Gastroenterology and Nutrition 53 , no. 3 (2011) : 310-319
Study Interventions
  • Fortified blended foods (FBF)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
Prado, E. L., Maleta, K., Ashorn, P., Ashorn, U., Vosti, S. A., Sadalaki, J., Dewey, K. G.. "Effects of maternal and child lipid-based nutrient supplements on infant development: a randomized trial in Malawi ." American Journal of Clinical Nutrition 103 , no. 3 (2016) : 784-793
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
Prado, E. L., Adu-Afarwuah, S., Lartey, A., Ocansey, M., Ashorn, P., Vosti, S. A., Dewey, K. G.. "Effects of pre- and post-natal lipid-based nutrient supplements on infant development in a randomized trial in Ghana ." Early Human Development 99 (2016) : 43-51
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Adu-Afarwuah, S., Lartey, A., Okronipa, H., Peerson, J., Ashorn, P., Dewey, K.. "Effects of small-quantity lipid-based nutrient supplement on hemoglobin and iron status of pregnant Ghanaian women ." The FASEB Journal 29 , no. 1_Supplement (2015) : 39.5-
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Pregnant & Lactating Women
Iuel-Brockdorf, A. S., Draebel, T. A., Ritz, C., Fabiansen, C., Cichon, B., Brix Christensen, V., Yameogo, C., Oummani, R., Briend, A., Michaelsen, K. F., Ashorn, P., Filteau, S., Friis, H.. "Evaluation of the acceptability of improved supplementary foods for the treatment of moderate acute malnutrition in Burkina Faso using a mixed method approach ." Appetite 99 (2016) : 34-45
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Trehan, I., Banerjee, S., Murray, E.. "Extending supplementary feeding for children younger than 5 years with moderate acute malnutrition leads to lower relapse rates ." Journal of Pediatric Gastroenterology & Nutrition 60 , no. 4 (2015) : 544-549
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Kerac, M., Bunn, J., Chagaluka, G., Bahwere, P., Tomkins, A., Collins, S., Seal, A.. "Follow-up of post-discharge growth and mortality after treatment for severe acute malnutrition (FuSAM study): a prospective cohort study ." PloS One 9 , no. 6 (2014) : e96030
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Banerjee, C., Hoq, M., Matin, E.. "Follow-up status of children with SAM treated with RUTF in peri-urban and rural Northern Bangladesh ." ENN Field Exchange , no. 50 (2015) : 9
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Smith, M. I., Yatsunenko, T., Manary, M. J., Trehan, I., Mkakosya, R., Cheng, J., Kau, A. L., Rich, S. S., Concannon, P., Mychaleckyj, J. C., Liu, J., Houpt, E., Li, J. V., Holmes, E., Nicholson, J., Knights, D., Ursell, L. K., Knight, R., Gordon, J. I.. "Gut microbiomes of Malawian twin pairs discordant for kwashiorkor ." Science 339 , no. 6119 (2013) : 548-554
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Hsieh, J. C., Liu, L., Zeilani, M., Ickes, S., Trehan, I., Maleta, K., Craig, C., Thakwalakwa, C., Singh, L., Brenna, J. T., Manary, M. J.. "High oleic ready-to-use therapeutic food maintains docosahexaenoic acid status in severe malnutrition: A randomized, blinded trial ." Journal of Pediatric Gastroenterology and Nutrition 61 , no. 1 (2015) : 138-143
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
Purwestri, R. C., Scherbaum, V., Inayati, D. A., Wirawan, N. N., Suryantan, J., Bloem, M. A., Pangaribuan, R. V., Stuetz, W., Hoffmann, V., Qaim, M., Biesalski, H. K., Bellows, A. C.. "Impact of daily versus weekly supply of locally produced ready-to-use food on growth of moderately wasted children on Nias Island, Indonesia ." ISRN Nutrition 2013 (2013) : 412145
Study Interventions
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
  • Innovation
  • Use
Nutritional Problems being Studied
  • MAM
Ickes, S. B., Adair, L. S., Brahe, C. A., Thirumurthy, H., Charles, B., Myhre, J. A., Bentley, M. E., Ammerman, A. S.. "Impact of lipid-based nutrient supplementation (LNS) on children's diet adequacy in Western Uganda ." Maternal & Child Nutrition 11 , no. S4 (2015) : 163-178
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • MAM
McNulty, Judiann, Harvey, Ruth, Tilford, Kathy. "Impact study report: Comparison of PM2A and MCHN approaches in SOUHARDO II ." (2015)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM
Pongcharoen, T., Ramakrishnan, U., DiGirolamo, A.M., Winichagoon, P., Flores, R., Singkhornard, J., Martorell, R.. "Influence of prenatal and postnatal growth on intellectual functioning in school-aged children ." Archives of Pediatrics & Adolescent Medicine 166 , no. 5 (2012) : 411-416
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Caulfield, L. E., Huffman, S. L., Piwoz, E. G.. "Interventions to improve intake of complementary foods by infants 6 to 12 months of age in developing countries: impact on growth and on the prevalence of malnutrition and potential contribution to child survival ." Food and Nutrition Bulletin 2 , no. 2 (1999) : 183-200
Study Interventions
  • Not Described
Research Gaps
  • Effectiveness
  • Efficacy
  • Use
Nutritional Problems being Studied
  • Stunted
  • MAM
Iannotti, L. L., Dulience, S. J. L., Green, J., Joseph, S., Francois, J., Antenor, M. L., Lesorogol, C., Mounce, J., Nickerson, N. M.. "Linear growth increased in young children in an urban slum of Haiti: a randomized controlled trial of a lipid-based nutrient supplement ." The American Journal of Clinical Nutrition 99 , no. 1 (2014) : 198-208
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted
Adu-Afarwuah, S., Lartey, A., Okronipa, H., Ashorn, P., Zeilani, M., Peerson, J. M., Arimond, M., Vosti, S., Dewey, K. G.. "Lipid-based nutrient supplement increases the birth size of infants of primiparous women in Ghana ." The American Journal of Clinical Nutrition 101 , no. 4 (2015) : 835-46
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Flax, V. L., Bentley, M. E., Chasela, C. S., Kayira, D., Hudgens, M. G., Kacheche, K. Z., Chavula, C., Kourtis, A. P., Jamieson, D. J., van der Horst, C. M.. "Lipid-based nutrient supplements are feasible as a breastmilk replacement for HIV-exposed infants from 24 to 48 weeks of age ." The Journal of Nutrition 143 , no. 5 (2013) : 701-707
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Hemsworth, J., Kumwenda, C., Arimond, M., Maleta, K., Phuka, J., Rehman, A. M., Vosti, S. A., Ashorn, U., Filteau, S., Dewey, K. G., Ashorn, P., Ferguson, E. L.. "Lipid-based nutrient supplements increase energy and macronutrient intakes from complementary food among Malawian infants ." The Journal of Nutrition 146 , no. 2 (2016) : 326-34
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted