Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 51 - 75 of 158 Results
Dewey, K. G., Arimond, M.. "Lipid-based nutrient supplements: how can they combat child malnutrition? ." PLoS Medicine 9 , no. 9 (2012) : e1001314
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • SAM
  • MAM
Singh, A. S., Kang, G., Ramachandran, A., Sarkar, R., Peter, P., Bose, A.. "Locally made ready to use therapeutic food for treatment of malnutrition a randomized controlled trial ." Indian Pediatrics 47 , no. 8 (2010)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • MAM
Scherbaum, V., Purwestri, R. C., Stuetz, W., Inayati, D. A., Suryantan, J., Bloem, M. A., Biesalski, H. K.. "Locally produced cereal/nut/legume-based biscuits versus peanut/milk-based spread for treatment of moderately to mildly wasted children in daily programmes on Nias Island, Indonesia: an issue of acceptance and compliance? ." Asia Pacific Journal of Clinical Nutrition 24 , no. 1 (2015) : 152
Study Interventions
  • Animal-source protein
  • Behavior change communication (BCC)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Acceptability
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • MAM
James, P. T., Van den Briel, N., Rozet, A., Israël, A. D., Fenn, B., Navarro-Colorado, C.. "Low‐dose RUTF protocol and improved service delivery lead to good programme outcomes in the treatment of uncomplicated SAM: a programme report from Myanmar ." Maternal & Child Nutrition 11 , no. 4 (2015) : 859-869
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Ackatia-Armah, R. S., McDonald, C. M., Doumbia, S., Erhardt, J. G., Hamer, D. H., Brown, K. H.. "Malian children with moderate acute malnutrition who are treated with lipid-based dietary supplements have greater weight gains and recovery rates than those treated with locally produced cereal-legume products: a community-based, cluster-randomized trial ." American Journal of Clinical Nutrition 101 , no. 3 (2015) : 632-645
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Sethuraman, K., Doledec, D., Begum, F., Manir, M. Z.. "Managing acute malnutrition: A review of the evidence and country experiences in South Asia and a recommended approach for Bangladesh ." FANTA Project (2014)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
  • Efficacy
Nutritional Problems being Studied
  • SAM
  • MAM
Tang, M., Sheng, X. Y., Krebs, N. F., Hambidge, K. M.. "Meat as complementary food for older breastfed infants and toddlers: a randomized, controlled trial in rural China ." Food and Nutrition Bulletin 35 , no. 4 Suppl (2014) : S188-192
Study Interventions
  • Animal-source protein
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Subramanian, S., Huq, S., Yatsunenko, T., Haque, R., Mahfuz, M., Alam, M. A., Benezra, A., DeStefano, J., Meier, M. F., Muegge, B. D., Barratt, M. J., VanArendonk, L. G., Zhang, Q., Province, M. A., Petri, W. A., Ahmed, T., Gordon, J. I.. "Persistent gut microbiota immaturity in malnourished Bangladeshi children ." Nature 510 , no. 7505 (2014) : 417-21
Study Interventions
  • Environmental enteric dysfunction (EED)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Phuka, John C, Maleta, Kenneth, Thakwalakwa, Chrissie, Cheung, Yin Bun, Briend, André, Manary, Mark J, Ashorn, Per. "Postintervention growth of Malawian children who received 12-mo dietary complementation with a lipid-based nutrient supplement or maize-soy flour ." The American Journal of Clinical Nutrition 89 , no. 1 (2009)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
Kerac, M., Seal, A.. "Preventing acute malnutrition in young children: Improving the evidence for current and future practice ." PLoS Medicine 11 , no. 9 (2014) : e1001715
Study Interventions
  • Animal-source protein
  • Cash transfer
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
  • MAM
Sayyad-Neerkorn, J., Langendorf, C., Roederer, T., Doyon, S., Mamaty, A., Woi-Messe, L., Manzo, M. L., Harouna, S., de Pee, S., Grais, R. F.. "Preventive effects of long-term supplementation with 2 nutritious food supplements in young children in Niger ." The Journal of Nutrition 145 , no. 11 (2015) : 2596-2603
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Mangani, C., Cheung, Y. B., Maleta, K., Phuka, J., Thakwalakwa, C., Dewey, K., Manary, M., Puumalainen, T., Ashorn, P.. "Providing lipid-based nutrient supplements does not affect developmental milestones among Malawian children ." Acta Paediatrica 103 , no. 1 (2014) : e17-26
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Maleta, K. M., Phuka, J., Alho, L., Cheung, Y. B., Dewey,K. G., Ashorn, U., Phiri, N., Phiri, T. E., Vosti, S. A., Zeilani, M., Kumwenda, C., Bendabenda, J., Pulakka, A., Ashorn, P.. "Provision of 10–40 g/d lipid-based nutrient supplements from 6 to 18 months of age does not prevent linear growth faltering in Malawi ." The Journal of Nutrition 145 , no. 8 (2015) : 1909-15
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Lakkam, M., Wager, S., Wise, P. H., Wein, L. M.. "Quantifying and exploiting the age dependence in the effect of supplementary food for child undernutrition ." PloS One 9 , no. 6 (2014) : e99632
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • MAM
Bisimwa, G., Owino, V. O., Bahwere, P., Dramaix, M., Donnen, P., Dibari, F., Collins, S.. "Randomized controlled trial of the effectiveness of a soybean-maize-sorghum-based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo ." American Journal of Clinical Nutrition 95 , no. 5 (2012) : 1157-1164
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • GAM
  • Stunted
Delchevalerie, P., Herp, M. V.. "Ready-to-use supplementary food versus corn soya blend with oil premix to treat moderate acute child malnutrition: a community-based cluster randomized trial ." (2007)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Medoua, G. N., Ntsama, P. M., Ndzana, A. C., Essa'a, V. J., Tsafack, J. J., Dimodi, H. T.. "Recovery rate of children with moderate acute malnutrition treated with ready-to-use supplementary food (RUSF) or improved corn–soya blend (CSB+): a randomized controlled trial ." Public Health Nutrition 19 , no. 2 (2016) : 363-370
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • MAM
Burza, S., Mahajan, R., Marino, E., Sunyoto, T., Shandilya, C., Tabrez, M., Kumar, K., Jha, A, Mathew, P., Salse, N., Casademont, C., Mishra, N. K.. "Seasonal effect and long-term nutritional status following exit from a Community-Based Management of Severe Acute Malnutrition program in Bihar, India ." European Journal of Clinical Nutrition 70 , no. 4 (2016) : 437-44
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Toe, L. C., Bouckaert, K. P., De Beuf, K., Roberfroid, D., Meda, N., Thas, O., Van Camp, J,, Kolsteren, P. W., Huybregts, L. F.. "Seasonality modifies the effect of a lipid-based nutrient supplement for pregnant rural women on birth length ." The Journal of Nutrition 145 , no. 3 (2015) : 634-639
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Maust, A., Koroma, A. S., Abla, C., Molokwu, N., Ryan, K. N., Singh, L., Manary, M. J.. "Severe and moderate acute malnutrition can be successfully managed with an integrated protocol in Sierra Leone ." The Journal of Nutrition 145 , no. 11 (2015) : 2604-2609
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • GAM
Fabiansen, C., Phelan, K. P., Cichon, B., Ritz, C., Briend, A., Michaelsen, K. F., Friis, H., Shepherd, S.. "Short children with a low midupper arm circumference respond to food supplementation: an observational study from Burkina Faso ." The American Journal of Clinical Nutrition 103 , no. 2 (2016) : 415-421
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • MAM
Hess, S. Y., Abbeddou, S., Jimenez, E. Y., Somé, J. W., Vosti, Stephen A, Ouédraogo, Z. P., Guissou, R. M., Ouédraogo, J., Brown, K. H.. "Small-quantity lipid-based nutrient supplements, regardless of their zinc content, increase growth and reduce the prevalence of stunting and wasting in young burkinabe children: a cluster-randomized trial ." PloS One 10 , no. 3 (2015) : e0122242
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM
Adu-Afarwuah, S., Lartey, A., Okronipa, H., Ashorn, P., Peerson, J. M., Arimond, M., Ashorn, U., Zeilani, M., Vosti, S., Dewey, K. G.. "Small-quantity, lipid-based nutrient supplements provided to women during pregnancy and 6 mo postpartum and to their infants from 6 mo of age increase the mean attained length of 18-mo-old children in semi-urban Ghana: a randomized controlled trial ." The American Journal of Clinical Nutrition 104 , no. 3 (2016) : 797-808
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Pandya, V. P., Joshi, I. V., Sheth, A. M., Kadri, A. M.. "Studying the effectiveness of mixed models of community based and institutional based interventions for management of severe acute malnourished children ." International Journal of Research in Medical Sciences 3 , no. 7 (2015) : 1758-1764
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
  • Other
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
Phuka, J., Thakwalakwa, C., Maleta, K., Cheung, Y. B., Briend, A., Manary, M., Ashorn, P.. "Supplementary feeding with fortified spread among moderately underweight 6-18-month-old rural Malawian children ." Maternal & Child Nutrition 5 , no. 2 (2009) : 159-70
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM