Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 76 - 100 of 158 Results
Matilsky, D. K., Maleta, K., Castleman, T., Manary, M. J.. "Supplementary feeding with fortified spreads results in higher recovery rates than with a corn/soy blend in moderately wasted children ." The Journal of Nutrition 139 , no. 4 (2009) : 773-778
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Purwestri, R. C., Scherbaum, V., Inayati, D. A., Wirawan, N. N., Suryantan, J., Bloem, M. A., Pangaribuan, R. V., Stuetz, W., Hoffmann, V., Qaim, M., Biesalski, H. K., Bellows, A. C.. "Supplementary feeding with locally-produced ready-to-use food (RUF) for mildly wasted children on Nias island, Indonesia: Comparison of daily and weekly program outcomes ." Asia Pacific Journal of Clinical Nutrition 21 , no. 3 (2012) : 374
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • MAM
Huybregts, L., Houngbé, F., Salpéteur, C., Brown, R., Roberfroid, D., Ait-Aissa, M., Kolsteren, P.. "The effect of adding ready-to-use supplementary food to a general food distribution on child nutritional status and morbidity: a cluster-randomized controlled trial ." PLoS Medicine 9 , no. 9 (2012) : e1001313
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Zimmermann, M. B., Chassard, C., Rohner, F., N'Goran, E. K., Nindjin, C., Dostal, A., Utzinger, J., Ghattas, H., Lacroix, C., Hurrell, R. F.. "The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'Ivoire ." American Journal of Clinical Nutrition 92 , no. 6 (2010) : 1406-1415
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Steenkamp, L., Lategan, R., Raubenheimer, J.. "The impact of Ready-to-Use Supplementary Food (RUSF) in targeted supplementation of children with moderate acute malnutrition (MAM) in South Africa ." South African Family Practice 57 , no. 5 (2015) : 322-325
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Tonguet-Papucci, A., Huybregts, L., Aissa, M. A.. "The MAM'Out project: a randomized controlled trial to assess multiannual and seasonal cash transfers for the prevention of acute malnutrition in children ." BMC Public Health (2015)
Study Interventions
  • Cash transfer
Research Gaps
  • Cost
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • MAM
Fenn, B., Sangrasi, G. M., Puett, C., Trenouth, L., Pietzsch, S.. "The REFANI Pakistan study-a cluster randomised controlled trial of the effectiveness and cost-effectiveness of cash-based transfer programmes on child nutrition status: study protocol ." BMC Public Health 15 , no. 1 (2015) : 1044
Study Interventions
  • Behavior change communication (BCC)
  • Cash transfer
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Cost
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • MAM
Bechman, A., Phillips, R. D., Chen, J.. "The use of nutrient-optimizing/cost-minimizing software to develop ready-to-use therapeutic foods for malnourished pregnant women in Mali ." Food Science & Nutrition 3 , no. 2 (2015) : 110-119
Study Interventions
  • Locally produced
  • Plant-source protein
Research Gaps
  • Cost
  • Effectiveness
Nutritional Problems being Studied
  • Pregnant & Lactating Women
Karakochuk, C., van den Briel, T., Stephens, D., Zlotkin, S.. "Treatment of moderate acute malnutrition with ready-to-use supplementary food results in higher overall recovery rates compared with a corn-soya blend in children in southern Ethiopia: an operations research trial ." The American Journal of Clinical Nutrition 96 , no. 4 (2012) : 911-6
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Barth-Jaeggi, T., Moretti, D., Kvalsvig, J., Holding, P. A., Njenga, J., Mwangi, A., Chhaga, M. K., Lacroix, C., Zimmermann, M. B.. "In-home fortification with 2.5 mg iron as NaFeEDTA does not reduce anaemia but increases weight gain: a randomised controlled trial in Kenyan infants ." Maternal & Child Nutrition 11 , no. S4 (2015) : 151-162
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Cames, C., Varloteaux, M., Have, N. N., Diom, A. B.,, Msellati, P., Mbaye, N., Mbodji, H., Sy Signate, H., Diack, A., ANRS 12279 MAGGSEN Cohort Study. "Acceptability of outpatient ready-to-use food-based protocols in HIV-infected Senegalese children and adolescents within the MAGGSEN cohort study ." Food and Nutrition Bulletin (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • SAM
  • MAM
Chavasit, V., Porasuphatana, S., Suthutvoravut, U., Zeder, C., Hurrell, R.. "Iron bioavailability in 8-24-month-old Thai children from a micronutrient-fortified quick-cooking rice containing ferric ammonium citrate or a mixture of ferrous sulphate and ferric sodium ethylenediaminetetraacetic acid ." Maternal & Child Nutrition 11 , no. S4 (2015) : 179-187
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Choudhury, N., Bromage, S., Alam, M. A., Shamsir Ahmed, A. M., Munirul Islam, M., Iqbal Hossain, M., Mahfuz, M., Mondal, D., Ahmed, T.. "Intervention study shows suboptimal growth among children receiving a food supplement for five months in a slum in Bangladesh ." Acta Paediatrica 105 , no. 10 (2016) : e464-e473
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Flax, V. L., Siega-Riz, A. M., Reinhart, G. A., Bentley, M. E.. "Provision of lipid-based nutrient supplements to Honduran children increases their dietary macro- and micronutrient intake without displacing other foods. ." Maternal & Child Nutrition 11 , no. S4 (2015) : 203-213
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Leroy, J. L., Olney, D. K., Ruel, M. T.. "Tubaramure, a food-assisted integrated health and nutrition program in Burundi, increases maternal and child hemoglobin concentrations and reduces anemia: A theory-based cluster-randomized controlled intervention trial  ." Journal of Nutrition 146 , no. 8 (2016) : 1601-1608
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Osei, A. K., Pandey, P., Spiro, D., Adhikari, D., Haselow, N., De Morais, C., Davis, D.. "Adding multiple micronutrient powders to a homestead food production programme yields marginally significant benefit on anaemia reduction among young children in Nepal ." Maternal & Child Health 11 , no. S4 (2015) : 188-202
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Rahman, A. S., Ahmed, T., Ahmed, F., Alam, M. S., Wahed, M. A., Sack, D. A.. "Double-blind cluster randomised controlled trial of wheat flour chapatti fortified with micronutrients on the status of vitamin A and iron in school-aged children in rural Bangladesh ." Maternal & Child Nutrition 11 , no. S4 (2015) : 120-131
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Yousafzai, A. K., Obradović, J., Rashee, M. A., Rizvi, A., Portilla, X. A., Tirado-Strayer, N., Siyal, S., Memon, U.. "Effects of responsive stimulation and nutrition interventions on children's development and growth at age 4 years in a disadvantaged population in Pakistan: A longitudinal follow-up of a cluster-randomised factorial effectiveness trial ." The Lancet Global Health 4 , no. 8 (2016) : e548-e558
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Koroma, A., Manary, M., Marron, B., Green, J., Rogers, B., Walton, S., Chui, K. H. K., Suri, D., Langlois, B., Jayson, L., Boiteau, J., Rosenberg, I., de Pee, S., Vosti, S., Webb, P.. "Comparison of four supplementary foods in treating moderate acute malnutrition in Sierra Leone: an Ebola-constrained cluster-randomized, controlled clinic-based effectiveness trial: A Report from the Food Aid Quality Review ." (2015)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Cost
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • MAM
Bailey, J., Chase, R., Kerac, M., Briend, A., Manary, M., Opondo, C., Gallagher, M., Kim, A.. "Combined protocol for SAM/MAM treatment: The ComPAS study ." ENN Online Field Exchange No. 53 (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
  • MAM
Moramarco, S., Amerio, G., Ciarlantini, C., Chipoma, J. K., Simpungwe, M. K., Nielsen-Saines, K., Palombi, L., Buonomo, E.. "Community-based management of child malnutrition in Zambia: HIV/AIDS infection and other risk factors on child survival ." International Journal of Environmental Research and Public Health 13 , no. 7 (2016)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
  • MAM
Nisbett, N., Longhurst, R., Barnett, I., Feruglio, F., Gordon, J., Hoddinott, J., Jahan, F., Karachiwalla, N., Roy, S., Shah, V., Siddiki, O. F., Tranchant, J. P., White, J.. "Impact evaluation of the DFID Programme to accelerate improved nutrition for the extreme poor in Bangladesh: Final Report ." DFID (2016)
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
Dani, V., Stav, A., Pendharkar, J., Satav, K., Sadanshiv, A., Adhav, A. S., Thakare, B.. "Community-based management of severe malnutrition: SAM and SUW in children under five in the Melghat tribal area, central India ." ENN Field Exchange 52 (2016) : 27
Study Interventions
  • Behavior change communication (BCC)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
Jie, C.. "Improve nutrition, food safety, and food security for China’s most vulnerable women and children – Joint final evaluation ." International Labor Office - Evaluation Unit (2013)
Study Interventions
  • Micronutrient powders (MNP)
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Wang, A. Z., Shulman, R. J., Crocker, A. H., Thakwalakwa, C., Maleta, K. M., Devaraj, S., Manary, M., Trehan, I.. "A combined intervention of zinc, multiple micronutrients, and Albendazole does not ameliorate environmental enteric dysfunction or stunting in rural Malawian children in a double-blind randomized controlled trial ." The Journal of Nutrition 147 , no. 1 (2017) : 97-103
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted