Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 26 - 50 of 260 Results
Babirekere-Iriso, E., Mortensen, C. G., Mupere, E., Rytter, M. J., Namusoke, H., Michaelsen, K. F., Briend, A., Stark, K. D., Friis, H., Lauritzen, L.. "Changes in whole-blood PUFA and their predictors during recovery from severe acute malnutrition ." The British Journal of Nutrition 115 , no. 10 (2016) : 1730-9
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Chang, C. Y., Trehan, I., Wang, R. J., Thakwalakwa, C., Maleta, K., Deitchler, M., Manary, M. J.. "Children successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery ." The Journal of Nutrition 143 , no. 2 (2013) : 215-220
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Mehta, B., Imran, A.. "Clinical and anthropometric profile of severe acute malnourished children on therapeutic intervention with WHO/UNICEF recommended therapeutic food ." International Journal of Science and Research 4 , no. 4 (2014) : 268-273
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Portillo-Reyes, V., Pérez-García, M., Loya-Méndez, Y., Puente, A. E.. "Clinical significance of neuropsychological improvement after supplementation with omega-3 in 8–12 years old malnourished Mexican children: A randomized, double-blind, placebo and treatment clinical trial ." Research in Developmental Disabilities 35 , no. 4 (2014) : 861-870
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Burza, S., Mahajan, R., Marino, E., Sunyoto, T., Shandilya, C., Tabrez, M., Kumari, K., Mathew, P., Jha, A., Salse, N., Mishra, K. N., Marino, E.101. "Community-based management of severe acute malnutrition in India: new evidence from Bihar ." The American Journal of Clinical Nutrition 101 , no. 4 (2015) : 847-859
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Ige, O. K., Oladokun, R. E., Kikelomo, O.. "Comparative weight gain with ready-to-use therapeutic food in stunted HIV-infected and-uninfected children in a Nigerian Hospital ." South African Journal of Child Health 8 , no. 3 (2014) : 104-107
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Manary, M., Chang, C.. "Comparing milk-fortified corn-soy blend (CSB++), soy ready-to-use supplementary food (RUSF), and soy/whey RUSF (Supplementary Plumpy®) in the treatment of moderate acute malnutrition ." FANTA Project (2012)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
Nutritional Problems being Studied
  • MAM
Marron, B., Green, J., Jayson, L., Suri, D., Marcus, S., Boiteau, J., Manary, M., Webb, P., Rogers, B.. "Comparison of four different supplementary foods in the treatment of moderate acute malnutrition (MAM) in children under five in Sierra Leone ." The FASEB Journal 29 , no. 1 (2015)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Langendorf, C., Roederer, T., de Pee, S., Brown, D., Doyon, S., Mamaty, A., Touré, L. W., Manzo, M. L., Grais, R. F.. "Preventing acute malnutrition among young children in crises: A prospective intervention study in Niger ." PLOS Medicine (2012)
Study Interventions
  • Animal-source protein
  • Cash transfer
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
  • MAM
Diop, E. H. I., Dossou, N. I., Ndour, M. M., Briend, A., Wade, S.. "Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: A randomized trial ." American Journal of Clinical Nutrition 78 , no. 2 (2003) : 302-307
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Puett, C., Sadler, K., Alderman, H., Coates, J., Fiedler, J. L., Myatt, M.. "Cost-effectiveness of the community-based management of severe acute malnutrition by community health workers in southern Bangladesh ." Health Policy and Planning 28 , no. 4 (2013) : 386-399
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Cost
Nutritional Problems being Studied
  • SAM
Ahmed, T., Choudhury, N., Hossain, M. I., Tangsuphoom, N., Islam, M. M., de Pee, S., Steiger, G., Fuli, R., Sarker, S. A. M., Parveen, M., West, K. P., Christian, P.. "Development and acceptability testing of ready-to-use supplementary food made from locally available food ingredients in Bangladesh ." BMC Pediatrics 14 , no. 1 (2014) : 164
Study Interventions
  • Locally produced
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Stunted
Phuka, J. C., Gladstone, M., Maleta, K., Thakwalakwa, C., Cheung, Y. B., Briend, A., Manary, M. J., Ashorn, P.. "Developmental outcomes among 18‐month‐old Malawians after a year of complementary feeding with lipid‐based nutrient supplements or corn‐soy flour ." Maternal & Child Nutrition 8 , no. 2 (2012) : 239-248
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Ruel, M. T., Menon, P., Loechl, C., Pelto, G.. "Donated fortified cereal blends improve the nutrient density of traditional complementary foods in Haiti, but iron and zinc gaps remain for infants ." Food and Nutrition Bulletin 25 , no. 4 (2004) : 361-376
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted
Khan, A. I. , Kabir, I., Hawkesworth, S., Ekström, E., Arifeen, S., Frongillo, E. A., Persson, L. A.. "Early invitation to food and/or multiple micronutrient supplementation in pregnancy does not affect body composition in offspring at 54 months: follow-up of the MINIMat randomised trial, Bangladesh ." Maternal & Child Nutrition 11 , no. 3 (2013) : 385-397
Study Interventions
  • Micronutrient powders (MNP)
  • Other
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
  • GAM
Lebenthal, Y., Yackobovitch-Gavan, M., Lazar, L., Shalitin, S., Tenenbaum, A., Shamir, R., Phillip, M.. "Effect of a nutritional supplement on growth in short and lean prepubertal children: a prospective, randomized, double-blind, placebo-controlled study ." The Journal of Pediatrics 165 , no. 6 (2014) : 1190-1193.e1
Study Interventions
  • Animal-source protein
  • Other
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Christian, P., Shaikh, S., Shamim, A. A., Mehra, S., Wu, L., Merrill, R. D., Klemm, R., Schulze, K., Pee, S., Ahmed, T.. "Effect of fortified complementary food supplementation on child growth in rural Bangladesh: A cluster-randomized trial ." The FASEB Journal 29 , no. 1 Supplement (2015) : 120.5
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Omollo, S. A.. "Effect of improved complementary foods on lean body mass, essential fatty acids, and gross motor development of Kenyan infants ." University of Nairobi Institute of Tropical and Infectious Diseases (2014)
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • MAM
Grellety, E., Shepherd, S., Roederer, T., Manzo, M. L., Doyon, S., Ategbo, E., Grais, R. F.. "Effect of mass supplementation with ready-to-use supplementary food during an anticipated nutritional emergency ." PloS One 7 , no. 9 (2012) : e44549
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted
  • GAM
Isanaka, S., Nombela, N.ohelly, Djibo, A., Poupard, M., Van Beckhoven, D., Gaboulaud, V., Guerin, P. J., Grais, R. F.. "Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial. ." Journal of the American Medical Association 301 , no. 3 (2009) : 277-85
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • GAM
Prudhon, C., Langendorf, C., Roederer, T., Doyon, S., Mamaty, A., Woi-Messe, L., Manzo, M. L., de Pee, S., Grais, R. F.. "Effect of ready-to-use foods for preventing child undernutrition in Niger: analysis of a prospective intervention study over 15 months of follow-up ." Maternal & Child Nutrition 13 , no. 1 (2016)
Study Interventions
  • Cash transfer
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • SAM
  • MAM
van der Kam, S., Roll, S., Swarthout, T., Edyegu-Otelu, G., Matsumoto, A., Kasujja, F. X., Casademont, C., Shanks, L., Salse-Ubach, N.. "Effect of short-term supplementation with ready-to-use therapeutic food or micronutrients for children after illness for prevention of malnutrition: a randomised controlled trial in Uganda ." PLoS Medicine 13 , no. 2 (2016) : e1001951
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Siega-Riz, A. M., Estrada Del Campo, Y., Kinlaw, A., Reinhart, G. A., Allen, L. H., Shahab-Ferdows, S., Heck, J., Suchindran, C. M., Bentley, M. E.. "Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6-18 months living in the rural region of Intibucá, Honduras ." Paediatric and Perinatal Epidemiology 28 , no. 3 (2014) : 245-254
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Clavier-Rogez, S., Rogez, J. B., Labrin, L., Branger, B., Dabadie, A.. "Effectiveness of a nutritional program based upon a ready-to-use therapeutic food in Chad ." Archives de Pédiatrie: organe officiel de la Sociéte française de pédiatrie 22 , no. 12 (2015) : 1247-1255
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • SAM
Shewade, H. D., Patro, B. K., Bharti, B., Soundappan, K., Kaur, A., Taneja, N.. "Effectiveness of indigenous ready-to-use therapeutic food in community-based management of uncomplicated severe acute malnutrition: a randomized controlled trial from India ." Journal of Tropical Pediatrics 59 , no. 5 (2013) : 393-8
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM