Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!



Community-based management of severe acute malnutrition in India: new evidence from Bihar

Burza, S., Mahajan, R., Marino, E., Sunyoto, T., Shandilya, C., Tabrez, M., Kumari, K., Mathew, P., Jha, A., Salse, N., Mishra, K. N., Marino, E.101. "Community-based management of severe acute malnutrition in India: new evidence from Bihar." The American Journal of Clinical Nutrition 101 , no. 4 (2015) : 847-859
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Countries
  • India
Nutritional Problems
  • SAM

Community-based management of severe malnutrition: SAM and SUW in children under five in the Melghat tribal area, central India

Dani, V., Stav, A., Pendharkar, J., Satav, K., Sadanshiv, A., Adhav, A. S., Thakare, B.. "Community-based management of severe malnutrition: SAM and SUW in children under five in the Melghat tribal area, central India." ENN Field Exchange 52 (2016) : 27
Study Interventions
  • Behavior change communication (BCC)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • India
Nutritional Problems
  • SAM

Comparative weight gain with ready-to-use therapeutic food in stunted HIV-infected and-uninfected children in a Nigerian Hospital

Ige, O. K., Oladokun, R. E., Kikelomo, O.. "Comparative weight gain with ready-to-use therapeutic food in stunted HIV-infected and-uninfected children in a Nigerian Hospital." South African Journal of Child Health 8 , no. 3 (2014) : 104-107
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Countries
  • Nigeria
Nutritional Problems
  • SAM

Comparing milk-fortified corn-soy blend (CSB++), soy ready-to-use supplementary food (RUSF), and soy/whey RUSF (Supplementary Plumpy®) in the treatment of moderate acute malnutrition

Manary, M., Chang, C.. "Comparing milk-fortified corn-soy blend (CSB++), soy ready-to-use supplementary food (RUSF), and soy/whey RUSF (Supplementary Plumpy®) in the treatment of moderate acute malnutrition." FANTA Project (2012)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
Countries
  • Malawi
Nutritional Problems
  • MAM

Comparison of four different supplementary foods in the treatment of moderate acute malnutrition (MAM) in children under five in Sierra Leone

Marron, B., Green, J., Jayson, L., Suri, D., Marcus, S., Boiteau, J., Manary, M., Webb, P., Rogers, B.. "Comparison of four different supplementary foods in the treatment of moderate acute malnutrition (MAM) in children under five in Sierra Leone." The FASEB Journal 29 , no. 1 (2015)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Countries
  • Burkina Faso
Nutritional Problems
  • MAM

Comparison of four supplementary foods in treating moderate acute malnutrition in Sierra Leone: an Ebola-constrained cluster-randomized, controlled clinic-based effectiveness trial: A Report from the Food Aid Quality Review

Koroma, A., Manary, M., Marron, B., Green, J., Rogers, B., Walton, S., Chui, K. H. K., Suri, D., Langlois, B., Jayson, L., Boiteau, J., Rosenberg, I., de Pee, S., Vosti, S., Webb, P.. "Comparison of four supplementary foods in treating moderate acute malnutrition in Sierra Leone: an Ebola-constrained cluster-randomized, controlled clinic-based effectiveness trial: A Report from the Food Aid Quality Review." (2015)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Cost
  • Effectiveness
  • Use
Countries
  • Sierra Leone
Nutritional Problems
  • MAM

Comparison of methods to assess adherence to small-quantity lipid-based nutrient supplements (SQ-LNS) and dispersible tablets among young Burkinabé children participating in a community-based intervention trial

Abbeddou, S., Hess, S. Y., Yakes Jimenez, E., Somé, J. W., Vosti, S. A., Guissou, R. M., Ouedragogo, J. B., Brown, K. H.. "Comparison of methods to assess adherence to small-quantity lipid-based nutrient supplements (SQ-LNS) and dispersible tablets among young Burkinabé children participating in a community-based intervention trial." Maternal & Child Nutrition 11 , no. S4 (2015) : 90-104
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Use
Countries
  • Burkina Faso
Nutritional Problems
  • Stunted

Comparison of ready-to-use therapeutic food with cereal legume-based Khichri among malnourished children

Dube, B., Rongsen, T., Mazumder, S., Taneja, S., Rafiqui, F., Bhandari, N., Bhan, M. K.. "Comparison of ready-to-use therapeutic food with cereal legume-based Khichri among malnourished children." Indian Pediatrics 46 (2009) : 383-388
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Composition
  • Innovation
Countries
  • India
Nutritional Problems
  • MAM

Comparison of the effectiveness of a milk-free soy-maize-sorghum-based ready-to-use therapeutic food to standard ready-to-use therapeutic food with 25% milk in nutrition management of severely acutely malnourished Zambian children: an equivalence non-blinded cluster randomised controlled trial

Irena, A., Bahwere, P., Owino, V., Diop, E. I., Bachmann, M., Mbwili-Muleya, C., Dibari, F., Sadler, K., Collins, S.. "Comparison of the effectiveness of a milk-free soy-maize-sorghum-based ready-to-use therapeutic food to standard ready-to-use therapeutic food with 25% milk in nutrition management of severely acutely malnourished Zambian children: an equivalence non-blinded cluster randomised controlled trial." Maternal & Child Nutrition 11 , no. S4 (2015) : 105-119
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Cost
  • Efficacy
Countries
  • Zambia
Nutritional Problems
  • SAM

Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: A randomized trial

Diop, E. H. I., Dossou, N. I., Ndour, M. M., Briend, A., Wade, S.. "Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: A randomized trial." American Journal of Clinical Nutrition 78 , no. 2 (2003) : 302-307
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Efficacy
Countries
  • Senegal
Nutritional Problems
  • SAM

Considerations in developing lipid-based nutrient supplements for prevention of undernutrition: experience from the International Lipid-Based Nutrient Supplements (iLiNS) Project

Arimond, M., Zeilani, M., Jungjohann, S., Brown, K. H., Ashorn, P., Allen, L. H., Dewey, K. G.. "Considerations in developing lipid-based nutrient supplements for prevention of undernutrition: experience from the International Lipid-Based Nutrient Supplements (iLiNS) Project." Maternal & Child Nutrition 11 , no. S4 (2015) : 31-61
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Acceptability
  • Composition
Countries
  • Malawi
  • Burkina Faso
  • Ghana
Nutritional Problems
  • Stunted

Cost analysis of the treatment of severe acute malnutrition in West Africa

Isanka, S., Menzies, N. A., Sayyad, J., Ayoola, M., Grais, R. F., Doyon, S.. "Cost analysis of the treatment of severe acute malnutrition in West Africa." Maternal & Child Nutrition (2016)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Cost
Countries
  • Niger
Nutritional Problems
  • SAM

Cost-effectiveness of the community-based management of severe acute malnutrition by community health workers in southern Bangladesh

Puett, C., Sadler, K., Alderman, H., Coates, J., Fiedler, J. L., Myatt, M.. "Cost-effectiveness of the community-based management of severe acute malnutrition by community health workers in southern Bangladesh." Health Policy and Planning 28 , no. 4 (2013) : 386-399
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Cost
Countries
  • Bangladesh
Nutritional Problems
  • SAM

Delivering Sprinkles Plus through the Integrated Child Development Services (ICDS) to Reduce Anemia in Pre-school Children in India

Hirve, S., Martini, E., Juvekar, S. K., Agarwal, D., Bavdekar, A., Sari, M., Molwane, M., Janes, S., Haselow, N., Yeung, D. L., Pandit, A.. "Delivering Sprinkles Plus through the Integrated Child Development Services (ICDS) to Reduce Anemia in Pre-school Children in India." The Indian Journal of Pediatrics 80 , no. 12 (2013) : 990-995
Study Interventions
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
  • Use
Countries
  • India
Nutritional Problems
  • Stunted
  • GAM

Development and acceptability of a novel milk-free soybean-maize-sorghum ready-to-use therapeutic food (SMS-RUTF) based on industrial extrusion cooking process

Owino, V. O., Irena, A. H., Dibari, F., Collins, S.. "Development and acceptability of a novel milk-free soybean-maize-sorghum ready-to-use therapeutic food (SMS-RUTF) based on industrial extrusion cooking process." Maternal & Child Health 10 , no. 1 (2014) : 126-134
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Acceptability
  • Innovation
Countries
  • Zambia
Nutritional Problems
  • SAM