Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!



Development and acceptability testing of ready-to-use supplementary food made from locally available food ingredients in Bangladesh

Ahmed, T., Choudhury, N., Hossain, M. I., Tangsuphoom, N., Islam, M. M., de Pee, S., Steiger, G., Fuli, R., Sarker, S. A. M., Parveen, M., West, K. P., Christian, P.. "Development and acceptability testing of ready-to-use supplementary food made from locally available food ingredients in Bangladesh." BMC Pediatrics 14 , no. 1 (2014) : 164
Study Interventions
  • Locally produced
  • Plant-source protein
Research Gaps
  • Acceptability
Countries
  • Bangladesh
Nutritional Problems
  • Stunted

Development of a locally produced, balanced protein-energy food-based supplement and its acceptance by undernourished pregnant women in Northern Bangladesh

Stevens, B., Watt, K., Brimblecombe, J., Clough, A., Judd, J.. "Development of a locally produced, balanced protein-energy food-based supplement and its acceptance by undernourished pregnant women in Northern Bangladesh." Journal of Hunger & Environmental Nutrition (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Innovation
Countries
  • Bangladesh
Nutritional Problems
  • Pregnant & Lactating Women

Developmental outcomes among 18‐month‐old Malawians after a year of complementary feeding with lipid‐based nutrient supplements or corn‐soy flour

Phuka, J. C., Gladstone, M., Maleta, K., Thakwalakwa, C., Cheung, Y. B., Briend, A., Manary, M. J., Ashorn, P.. "Developmental outcomes among 18‐month‐old Malawians after a year of complementary feeding with lipid‐based nutrient supplements or corn‐soy flour." Maternal & Child Nutrition 8 , no. 2 (2012) : 239-248
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Countries
  • Malawi

Donated fortified cereal blends improve the nutrient density of traditional complementary foods in Haiti, but iron and zinc gaps remain for infants

Ruel, M. T., Menon, P., Loechl, C., Pelto, G.. "Donated fortified cereal blends improve the nutrient density of traditional complementary foods in Haiti, but iron and zinc gaps remain for infants." Food and Nutrition Bulletin 25 , no. 4 (2004) : 361-376
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
  • Use
Countries
  • Haiti
Nutritional Problems
  • Stunted

Double-blind cluster randomised controlled trial of wheat flour chapatti fortified with micronutrients on the status of vitamin A and iron in school-aged children in rural Bangladesh

Rahman, A. S., Ahmed, T., Ahmed, F., Alam, M. S., Wahed, M. A., Sack, D. A.. "Double-blind cluster randomised controlled trial of wheat flour chapatti fortified with micronutrients on the status of vitamin A and iron in school-aged children in rural Bangladesh." Maternal & Child Nutrition 11 , no. S4 (2015) : 120-131
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Effectiveness
Countries
  • Bangladesh
Nutritional Problems
  • Stunted

Early invitation to food and/or multiple micronutrient supplementation in pregnancy does not affect body composition in offspring at 54 months: follow-up of the MINIMat randomised trial, Bangladesh

Khan, A. I. , Kabir, I., Hawkesworth, S., Ekström, E., Arifeen, S., Frongillo, E. A., Persson, L. A.. "Early invitation to food and/or multiple micronutrient supplementation in pregnancy does not affect body composition in offspring at 54 months: follow-up of the MINIMat randomised trial, Bangladesh." Maternal & Child Nutrition 11 , no. 3 (2013) : 385-397
Study Interventions
  • Micronutrient products (MNP)
  • Other
Research Gaps
  • Innovation
Countries
  • Bangladesh
Nutritional Problems
  • Stunted
  • Pregnant & Lactating Women
  • GAM

Effect of a nutritional supplement on growth in short and lean prepubertal children: a prospective, randomized, double-blind, placebo-controlled study

Lebenthal, Y., Yackobovitch-Gavan, M., Lazar, L., Shalitin, S., Tenenbaum, A., Shamir, R., Phillip, M.. "Effect of a nutritional supplement on growth in short and lean prepubertal children: a prospective, randomized, double-blind, placebo-controlled study." The Journal of Pediatrics 165 , no. 6 (2014) : 1190-1193.e1
Study Interventions
  • Animal-source protein
  • Other
Research Gaps
  • Composition
  • Effectiveness
Countries
  • Israel
Nutritional Problems
  • Stunted

Effect of a package of health and nutrition services on sustained recovery in children after moderate acute malnutrition and factors related to sustaining recovery: a cluster-randomized trial

Stobaugh, H. C., Bollinger, L. B., Adams, S. E., Crocker, A. H., Grise, J. B., Kennedy, J. A., Thakwalakwa, C., Maleta, K. M., Dietzen, D. J., Manary, M. J., Trehan, I.. "Effect of a package of health and nutrition services on sustained recovery in children after moderate acute malnutrition and factors related to sustaining recovery: a cluster-randomized trial." American Journal of Clinical Nutrition (2017)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Malawi
Nutritional Problems
  • MAM

Effect of community-based food supplementation on improving growth of underweight children under five years of age in West Nusa Tenggara

Pulungan, A. B., Mirasanti, D. A.. "Effect of community-based food supplementation on improving growth of underweight children under five years of age in West Nusa Tenggara." Paediatrica Indonesiana 57 , no. 5 (2017) : 246-251
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Countries
  • Indonesia
Nutritional Problems
  • Stunted
  • GAM

Effect of daily versus once-weekly home fortification with micronutrient Sprinkles on hemoglobin and iron status among young children in rural Bangladesh

Ziauddin Hyder, S. M., Haseen, F., Rahman, M., Tondeur, M. C., Zlotkin, S. H.. "Effect of daily versus once-weekly home fortification with micronutrient Sprinkles on hemoglobin and iron status among young children in rural Bangladesh." Food and Nutrition Bulletin 28 , no. 7 (2007)
Study Interventions
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
Countries
  • Bangladesh
Nutritional Problems
  • Stunted
  • GAM

Effect of daily versus weekly home fortification with multiple micronutrient powder on haemoglobin concentration of young children in a rural area, Lao People’s Democratic Republic: a randomised trial

Kounnavong, S., Sunahara, T., Mascie-Taylor, C. G. N., Hasizume, M., Okumura, J., Moji, K., Boupha, B., Yamamoto, T.. "Effect of daily versus weekly home fortification with multiple micronutrient powder on haemoglobin concentration of young children in a rural area, Lao People’s Democratic Republic: a randomised trial." Nutrition Journal 10 , no. 129 (2011)
Study Interventions
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Laos
Nutritional Problems
  • Stunted
  • GAM

Effect of fortified complementary food supplementation on child growth in rural Bangladesh: A cluster-randomized trial

Christian, P., Shaikh, S., Shamim, A. A., Mehra, S., Wu, L., Merrill, R. D., Klemm, R., Schulze, K., Pee, S., Ahmed, T.. "Effect of fortified complementary food supplementation on child growth in rural Bangladesh: A cluster-randomized trial." The FASEB Journal 29 , no. 1 Supplement (2015) : 120.5
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Bangladesh
Nutritional Problems
  • Stunted
  • GAM

Effect of improved complementary foods on lean body mass, essential fatty acids, and gross motor development of Kenyan infants

Omollo, S. A.. "Effect of improved complementary foods on lean body mass, essential fatty acids, and gross motor development of Kenyan infants." University of Nairobi Institute of Tropical and Infectious Diseases (2014)
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Kenya
Nutritional Problems
  • Stunted
  • MAM

Effect of mass supplementation with ready-to-use supplementary food during an anticipated nutritional emergency

Grellety, E., Shepherd, S., Roederer, T., Manzo, M. L., Doyon, S., Ategbo, E., Grais, R. F.. "Effect of mass supplementation with ready-to-use supplementary food during an anticipated nutritional emergency." PloS One 7 , no. 9 (2012) : e44549
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Countries
  • Niger
Nutritional Problems
  • Stunted
  • GAM

Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial.

Isanaka, S., Nombela, N.ohelly, Djibo, A., Poupard, M., Van Beckhoven, D., Gaboulaud, V., Guerin, P. J., Grais, R. F.. "Effect of preventive supplementation with ready-to-use therapeutic food on the nutritional status, mortality, and morbidity of children aged 6 to 60 months in Niger: a cluster randomized trial.." Journal of the American Medical Association 301 , no. 3 (2009) : 277-85
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Countries
  • Niger
Nutritional Problems
  • GAM