Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 101 - 125 of 260 Results
Ashorn, U., Alho, L., Arimond, M., Dewey, K. G., Maleta, K., Phiri, N., Phuka, J., Vosti, S. A., Zeilani, M., Ashorn, P.. "Malawian mothers consider lipid-based nutrient supplements acceptable for children throughout a 1-year intervention, but deviation from user recommendations is common ." The Journal of Nutrition 145 , no. 7 (2015) : 1588-1595
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Stunted
Ackatia-Armah, R. S., McDonald, C. M., Doumbia, S., Erhardt, J. G., Hamer, D. H., Brown, K. H.. "Malian children with moderate acute malnutrition who are treated with lipid-based dietary supplements have greater weight gains and recovery rates than those treated with locally produced cereal-legume products: a community-based, cluster-randomized trial ." American Journal of Clinical Nutrition 101 , no. 3 (2015) : 632-645
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Sethuraman, K., Doledec, D., Begum, F., Manir, M. Z.. "Managing acute malnutrition: A review of the evidence and country experiences in South Asia and a recommended approach for Bangladesh ." FANTA Project (2014)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
  • Efficacy
Nutritional Problems being Studied
  • SAM
  • MAM
Tang, M., Sheng, X. Y., Krebs, N. F., Hambidge, K. M.. "Meat as complementary food for older breastfed infants and toddlers: a randomized, controlled trial in rural China ." Food and Nutrition Bulletin 35 , no. 4 Suppl (2014) : S188-192
Study Interventions
  • Animal-source protein
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Ray, S.. "Micronutrient supplementation, dietary intervention and resulting body weight gain of severe acute malnourished children–a pilot project study of OJUS Medical Institute ." Indian Journal of Community Health 26 , no. 6 (2014) : 160-165
Study Interventions
  • Locally produced
  • Micronutrient powders (MNP)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • SAM
Perignon, M., Fiorentino, M., Kuong, K., Chamnan, C., Parker, M., Burja, K., Berger, J., Wieringa, F. T.. "Multi-micronutrient fortified rice improved vitamin A status of Cambodian school children ." European Journal of Nutrition & Food Safety 5 , no. 5 (2015) : 832-833
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
Nutritional Problems being Studied
  • Stunted
Simpore, J., Kabore, F., Zongo, F., Dansou, D., Bere, A., Pignatelli, S., Biondi, D. M., Ruberto, G., Musumeci, S.. "Nutrition rehabilitation of undernourished children utilizing Spiruline and Misola ." Nutrition Journal 5 , no. 3 (2006)
Study Interventions
  • Locally produced
  • Other
Research Gaps
  • Composition
  • Innovation
Nutritional Problems being Studied
  • Stunted
Caparros Megido, R., Alabi, T., Nieus, C., Blecker, C., Danthine, ., Bogaert, J., Haubruge, E., Francis, F.. "Optimisation of a cheap and residential small‐scale production of edible crickets with local by‐products as an alternative protein‐rich human food source in Ratanakiri Province, Cambodia ." Journal of the Science of Food and Agriculture 96 , no. 2 (2015) : 627-632
Study Interventions
  • Animal-source protein
  • Locally produced
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
Ali, E., Zachariah, R., Dahmane, A., Van den Boogaard, W., Shams, Z., Akter, T., Alders, P., Manzi, M., Allaouna, M., Draguez, B., Delchevalerie, P., Harries, A. D.. "Peanut-based ready-to-use therapeutic food: acceptability among malnourished children and community workers in Bangladesh ." Public Health Action 3 , no. 2 (2013) : 128-135
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • SAM
  • MAM
Ali, E., Zachariah, R., Shams, Z., Manzi, M., Akter, T., Alders, P., Allaouna, M., Delchevalerie, P., Harries, A. D.. "Peanut-based ready-to-use therapeutic food: How acceptable and tolerated is it among malnourished pregnant and lactating women in Bangladesh? ." Maternal & Child Nutrition 11 , no. 4 (2015) : 1028-1035
Study Interventions
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Pregnant & Lactating Women
Tadesse, E., Berhane, Y., Hjern, A., Olsson, P., Ekström, E.. "Perceptions of usage and unintended consequences of provision of ready-to-use therapeutic food for management of severe acute child malnutrition. A qualitative study in Southern Ethiopia ." Health Policy and Planning 30 , no. 10 (2015) : 1334-1341
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Use
Nutritional Problems being Studied
  • SAM
Subramanian, S., Huq, S., Yatsunenko, T., Haque, R., Mahfuz, M., Alam, M. A., Benezra, A., DeStefano, J., Meier, M. F., Muegge, B. D., Barratt, M. J., VanArendonk, L. G., Zhang, Q., Province, M. A., Petri, W. A., Ahmed, T., Gordon, J. I.. "Persistent gut microbiota immaturity in malnourished Bangladeshi children ." Nature 510 , no. 7505 (2014) : 417-21
Study Interventions
  • Environmental enteric dysfunction (EED)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Phuka, John C, Maleta, Kenneth, Thakwalakwa, Chrissie, Cheung, Yin Bun, Briend, André, Manary, Mark J, Ashorn, Per. "Postintervention growth of Malawian children who received 12-mo dietary complementation with a lipid-based nutrient supplement or maize-soy flour ." The American Journal of Clinical Nutrition 89 , no. 1 (2009)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
Shamim, A. A., Hanif, Abu A. M., Merrill, R. D., Campbell, R. K., Kumkum, M. A., Shaikh, S., de Pee, S., Ahmed, T., Parveen, M., Mehra, S., Klemm, R. D. W., Labrique, A. B., West, K. P., Christian, P.. "Preferred delivery method and acceptability of Wheat-Soy Blend (WSB++) as a daily complementary food supplement in northwest Bangladesh ." Ecology of Food and Nutrition 54 , no. 1 (2015) : 74-92
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
Research Gaps
  • Acceptability
  • Innovation
  • Use
Nutritional Problems being Studied
  • Stunted
Kerac, M., Seal, A.. "Preventing acute malnutrition in young children: Improving the evidence for current and future practice ." PLoS Medicine 11 , no. 9 (2014) : e1001715
Study Interventions
  • Animal-source protein
  • Cash transfer
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
  • MAM
Sayyad-Neerkorn, J., Langendorf, C., Roederer, T., Doyon, S., Mamaty, A., Woi-Messe, L., Manzo, M. L., Harouna, S., de Pee, S., Grais, R. F.. "Preventive effects of long-term supplementation with 2 nutritious food supplements in young children in Niger ." The Journal of Nutrition 145 , no. 11 (2015) : 2596-2603
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Kerac, M., Bunn, J., Seal, A., Thindwa, M., Tomkins, A., Sadler, K., Bahwere, P., Collins, S.. "Probiotics and prebiotics for severe acute malnutrition (PRONUT study): a double-blind efficacy randomised controlled trial in Malawi ." The Lancet 374 , no. 9684 (2009) : 136-144
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Other
Research Gaps
  • Composition
  • Innovation
Nutritional Problems being Studied
  • SAM
Mangani, C., Cheung, Y. B., Maleta, K., Phuka, J., Thakwalakwa, C., Dewey, K., Manary, M., Puumalainen, T., Ashorn, P.. "Providing lipid-based nutrient supplements does not affect developmental milestones among Malawian children ." Acta Paediatrica 103 , no. 1 (2014) : e17-26
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Maleta, K. M., Phuka, J., Alho, L., Cheung, Y. B., Dewey,K. G., Ashorn, U., Phiri, N., Phiri, T. E., Vosti, S. A., Zeilani, M., Kumwenda, C., Bendabenda, J., Pulakka, A., Ashorn, P.. "Provision of 10–40 g/d lipid-based nutrient supplements from 6 to 18 months of age does not prevent linear growth faltering in Malawi ." The Journal of Nutrition 145 , no. 8 (2015) : 1909-15
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Lakkam, M., Wager, S., Wise, P. H., Wein, L. M.. "Quantifying and exploiting the age dependence in the effect of supplementary food for child undernutrition ." PloS One 9 , no. 6 (2014) : e99632
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • MAM
Bisimwa, G., Owino, V. O., Bahwere, P., Dramaix, M., Donnen, P., Dibari, F., Collins, S.. "Randomized controlled trial of the effectiveness of a soybean-maize-sorghum-based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo ." American Journal of Clinical Nutrition 95 , no. 5 (2012) : 1157-1164
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • GAM
  • Stunted
Iannotti, L. L., Henretty, N. M., Delnatus, J. R., Previl, W., Stehl, T., Vorkoper, S., Bodden, J., Maust, A., Smidt, R., Nash, M. L., Tamimie, C. A., Owen, B. C., Wolff, P. B.. "Ready-to-use supplementary food increases fat mass and BMI in Haitian school-aged children ." The Journal of Nutrition 145 , no. 4 (2015) : 813-822
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Other
Research Gaps
  • Composition
Nutritional Problems being Studied
  • Stunted
Delchevalerie, P., Herp, M. V.. "Ready-to-use supplementary food versus corn soya blend with oil premix to treat moderate acute child malnutrition: a community-based cluster randomized trial ." (2007)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Jones, K. D., Ali, R., Khasira, M. A., Odera, D., West, A. L., Koster, G., Akomo, P., Talbert, A. W., Goss, V. M., Ngari, M., Thitiri, J., Ndoro, S., Knight, M. A. G., Omollo, K., Ndungu, A., Mulongo, M. M., Bahwere, P., Fegan, G., Warner, J. O., Postle, A. D., Collins, S., Calder, P. C., Berkley, J. A.. "Ready-to-use therapeutic food with elevated n-3 polyunsaturated fatty acid content, with or without fish oil, to treat severe acute malnutrition: a randomized controlled trial ." BMC Medicine 13 , no. 1 (2015) : 93
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Other
Research Gaps
  • Composition
  • Innovation
Nutritional Problems being Studied
  • SAM
Shanka, N. A., Lemma, S., Abyu, D. M.. "Recovery rate and determinants in treatment of children with severe acute malnutrition using outpatient therapeutic feeding program in Kamba District, Ethiopia ." Journal of Nutritional Disorders & Therapy 5 , no. 2 (2015)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM