Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 126 - 150 of 260 Results
Medoua, G. N., Ntsama, P. M., Ndzana, A. C., Essa'a, V. J., Tsafack, J. J., Dimodi, H. T.. "Recovery rate of children with moderate acute malnutrition treated with ready-to-use supplementary food (RUSF) or improved corn–soya blend (CSB+): a randomized controlled trial ." Public Health Nutrition 19 , no. 2 (2016) : 363-370
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • MAM
Flax, V. L., Mäkinen, S., Ashorn, U., Cheung, Y. B., Maleta, K., Ashorn, P., Bentley, M. E.. "Responsive feeding and child interest in food vary when rural Malawian children are fed lipid‐based nutrient supplements or local complementary food ." Maternal & Child Nutrition 9 , no. 3 (2013) : 369-380
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • MAM
Isanaka, S., Langendorf, C., Berthé, F., Gnegne, S., Li, N., Ousmane, N., Harouna, S., Hassane, H., Schaefer, M., Adehossi, E., Grais, R. F.. "Routine amoxicillin for uncomplicated severe acute malnutrition in children ." The New England Journal of Medicine 374 (2016) : 444-453
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Other
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • SAM
Burza, S., Mahajan, R., Marino, E., Sunyoto, T., Shandilya, C., Tabrez, M., Kumar, K., Jha, A, Mathew, P., Salse, N., Casademont, C., Mishra, N. K.. "Seasonal effect and long-term nutritional status following exit from a Community-Based Management of Severe Acute Malnutrition program in Bihar, India ." European Journal of Clinical Nutrition 70 , no. 4 (2016) : 437-44
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Toe, L. C., Bouckaert, K. P., De Beuf, K., Roberfroid, D., Meda, N., Thas, O., Van Camp, J,, Kolsteren, P. W., Huybregts, L. F.. "Seasonality modifies the effect of a lipid-based nutrient supplement for pregnant rural women on birth length ." The Journal of Nutrition 145 , no. 3 (2015) : 634-639
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Maust, A., Koroma, A. S., Abla, C., Molokwu, N., Ryan, K. N., Singh, L., Manary, M. J.. "Severe and moderate acute malnutrition can be successfully managed with an integrated protocol in Sierra Leone ." The Journal of Nutrition 145 , no. 11 (2015) : 2604-2609
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • GAM
Fabiansen, C., Phelan, K. P., Cichon, B., Ritz, C., Briend, A., Michaelsen, K. F., Friis, H., Shepherd, S.. "Short children with a low midupper arm circumference respond to food supplementation: an observational study from Burkina Faso ." The American Journal of Clinical Nutrition 103 , no. 2 (2016) : 415-421
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • MAM
Hess, S. Y., Abbeddou, S., Jimenez, E. Y., Somé, J. W., Vosti, Stephen A, Ouédraogo, Z. P., Guissou, R. M., Ouédraogo, J., Brown, K. H.. "Small-quantity lipid-based nutrient supplements, regardless of their zinc content, increase growth and reduce the prevalence of stunting and wasting in young burkinabe children: a cluster-randomized trial ." PloS One 10 , no. 3 (2015) : e0122242
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • GAM
Adu-Afarwuah, S., Lartey, A., Okronipa, H., Ashorn, P., Peerson, J. M., Arimond, M., Ashorn, U., Zeilani, M., Vosti, S., Dewey, K. G.. "Small-quantity, lipid-based nutrient supplements provided to women during pregnancy and 6 mo postpartum and to their infants from 6 mo of age increase the mean attained length of 18-mo-old children in semi-urban Ghana: a randomized controlled trial ." The American Journal of Clinical Nutrition 104 , no. 3 (2016) : 797-808
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Bourdier, F.. "Socio-anthropological investigation related to the acceptability of Plumpy'nut in Cambodia ." Paris: institut de Recherche pour le Développement (2009)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • MAM
Leroy, J., Olney, D., Ruel, M.. "Strengthening and evaluating the Preventing Malnutrition in Children under 2 Years of Age approach – Burundi Follow-up Report: Children 0–23 Months ." FANTA III (2009)
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
Pandya, V. P., Joshi, I. V., Sheth, A. M., Kadri, A. M.. "Studying the effectiveness of mixed models of community based and institutional based interventions for management of severe acute malnourished children ." International Journal of Research in Medical Sciences 3 , no. 7 (2015) : 1758-1764
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
  • Other
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
Phuka, J., Thakwalakwa, C., Maleta, K., Cheung, Y. B., Briend, A., Manary, M., Ashorn, P.. "Supplementary feeding with fortified spread among moderately underweight 6-18-month-old rural Malawian children ." Maternal & Child Nutrition 5 , no. 2 (2009) : 159-70
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Matilsky, D. K., Maleta, K., Castleman, T., Manary, M. J.. "Supplementary feeding with fortified spreads results in higher recovery rates than with a corn/soy blend in moderately wasted children ." The Journal of Nutrition 139 , no. 4 (2009) : 773-778
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Purwestri, R. C., Scherbaum, V., Inayati, D. A., Wirawan, N. N., Suryantan, J., Bloem, M. A., Pangaribuan, R. V., Stuetz, W., Hoffmann, V., Qaim, M., Biesalski, H. K., Bellows, A. C.. "Supplementary feeding with locally-produced ready-to-use food (RUF) for mildly wasted children on Nias island, Indonesia: Comparison of daily and weekly program outcomes ." Asia Pacific Journal of Clinical Nutrition 21 , no. 3 (2012) : 374
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • MAM
Ashorn, P., Alho, L., Ashorn, U., Cheung, Y. B., Dewey, K. G., Gondwe, A., Harjunmaa, U., Lartey, A., Phiri, N., Phiri, T. E., Vosti, S. A., Zeilani, M., Maleta, K.. "Supplementation of maternal diets during pregnancy and for 6 months postpartum and infant diets thereafter with small-quantity lipid-based nutrient supplements does not promote child growth by 18 months of age in rural Malawi: A randomized controlled trial ." The Journal of Nutrition 145 , no. 6 (2015) : 1345-53
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Huybregts, L., Houngbé, F., Salpéteur, C., Brown, R., Roberfroid, D., Ait-Aissa, M., Kolsteren, P.. "The effect of adding ready-to-use supplementary food to a general food distribution on child nutritional status and morbidity: a cluster-randomized controlled trial ." PLoS Medicine 9 , no. 9 (2012) : e1001313
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Zimmermann, M. B., Chassard, C., Rohner, F., N'Goran, E. K., Nindjin, C., Dostal, A., Utzinger, J., Ghattas, H., Lacroix, C., Hurrell, R. F.. "The effects of iron fortification on the gut microbiota in African children: a randomized controlled trial in Cote d'Ivoire ." American Journal of Clinical Nutrition 92 , no. 6 (2010) : 1406-1415
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Ashorn, P., Alho, L., Ashorn, U., Cheung, Y. B., Dewey, K. G., Harjunmaa, U., Lartey, A., Nkhoma, M., Phiri, N., Phuka, J., Vosti, S. A., Zeilani, M., Maleta, K.. "The impact of lipid-based nutrient supplement provision to pregnant women on newborn size in rural Malawi: a randomized controlled trial ." The American Journal of Clinical Nutrition 101 , no. 2 (2015) : 387-97
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Steenkamp, L., Lategan, R., Raubenheimer, J.. "The impact of Ready-to-Use Supplementary Food (RUSF) in targeted supplementation of children with moderate acute malnutrition (MAM) in South Africa ." South African Family Practice 57 , no. 5 (2015) : 322-325
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Tonguet-Papucci, A., Huybregts, L., Aissa, M. A.. "The MAM'Out project: a randomized controlled trial to assess multiannual and seasonal cash transfers for the prevention of acute malnutrition in children ." BMC Public Health (2015)
Study Interventions
  • Cash transfer
Research Gaps
  • Cost
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • MAM
Jayson, L., Passarelli, S., Suri, D., Maganga, G., Marcus, S., Webb, P., Rogers, B.. "The price of oil: Behavior change communication and increased oil ration improve mothers' uses of vegetable oil in preparing food aid rations for children in Malawi ." The FASEB Journal 29 , no. 1 Supplement 898.21 (2015)
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
  • Other
Research Gaps
  • Innovation
  • Use
Nutritional Problems being Studied
  • MAM
Fenn, B., Sangrasi, G. M., Puett, C., Trenouth, L., Pietzsch, S.. "The REFANI Pakistan study-a cluster randomised controlled trial of the effectiveness and cost-effectiveness of cash-based transfer programmes on child nutrition status: study protocol ." BMC Public Health 15 , no. 1 (2015) : 1044
Study Interventions
  • Behavior change communication (BCC)
  • Cash transfer
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Cost
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • MAM
Skau, J. K. H., Bunthang, T., Chamnan, C., Wieringa, F. T., Dijkhuizen, M. A., Roos, N., Ferguson, E. L.. "The use of linear programming to determine whether a formulated complementary food product can ensure adequate nutrients for 6- to 11-month-old Cambodian infants ." The American Journal of Clinical Nutrition 99 , no. 1 (2014) : 130-8
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Locally produced
  • Plant-source protein
Nutritional Problems being Studied
  • Stunted
Bechman, A., Phillips, R. D., Chen, J.. "The use of nutrient-optimizing/cost-minimizing software to develop ready-to-use therapeutic foods for malnourished pregnant women in Mali ." Food Science & Nutrition 3 , no. 2 (2015) : 110-119
Study Interventions
  • Locally produced
  • Plant-source protein
Research Gaps
  • Cost
  • Effectiveness
Nutritional Problems being Studied
  • Pregnant & Lactating Women