Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!



Effect of providing multiple micronutrients in powder through primary healthcare on anemia in young Brazilian children: a multicentre pragmatic controlled trial

Cardoso, M. A., Augusto, R. A., Bortolini, G. A., Oliveira, C. S. M., Tietzman, D. C., Sequeira, L. A. S., Hadler, M C., Peixoto, M. R. G. , Muniz, P. T., Vitolo, M. R., Lira, P. I. C., Jamie, P. C., ENFAC Working Group. "Effect of providing multiple micronutrients in powder through primary healthcare on anemia in young Brazilian children: a multicentre pragmatic controlled trial." PLoS One 11 , no. 5 (2016) : e0156194
Study Interventions
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Brazil
Nutritional Problems
  • Stunted

Effect of ready-to-use foods for preventing child undernutrition in Niger: analysis of a prospective intervention study over 15 months of follow-up

Prudhon, C., Langendorf, C., Roederer, T., Doyon, S., Mamaty, A., Woi-Messe, L., Manzo, M. L., de Pee, S., Grais, R. F.. "Effect of ready-to-use foods for preventing child undernutrition in Niger: analysis of a prospective intervention study over 15 months of follow-up." Maternal & Child Nutrition 13 , no. 1 (2016)
Study Interventions
  • Cash transfer
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Niger
Nutritional Problems
  • Stunted
  • SAM
  • MAM

Effect of selected dietary regimens on recovery from moderate acute malnutrition in young Malian children

Ackatia-Armah, R. S., McDonald, C., Doumbia, S., Brown, K. H.. "Effect of selected dietary regimens on recovery from moderate acute malnutrition in young Malian children." The FASEB Journal 26 , no. 1 (2012)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Countries
  • Mali
Nutritional Problems
  • MAM

Effect of short-term supplementation with ready-to-use therapeutic food or micronutrients for children after illness for prevention of malnutrition: a randomised controlled trial in Uganda

van der Kam, S., Roll, S., Swarthout, T., Edyegu-Otelu, G., Matsumoto, A., Kasujja, F. X., Casademont, C., Shanks, L., Salse-Ubach, N.. "Effect of short-term supplementation with ready-to-use therapeutic food or micronutrients for children after illness for prevention of malnutrition: a randomised controlled trial in Uganda." PLoS Medicine 13 , no. 2 (2016) : e1001951
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
Countries
  • Uganda
Nutritional Problems
  • MAM

Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6-18 months living in the rural region of Intibucá, Honduras

Siega-Riz, A. M., Estrada Del Campo, Y., Kinlaw, A., Reinhart, G. A., Allen, L. H., Shahab-Ferdows, S., Heck, J., Suchindran, C. M., Bentley, M. E.. "Effect of supplementation with a lipid-based nutrient supplement on the micronutrient status of children aged 6-18 months living in the rural region of Intibucá, Honduras." Paediatric and Perinatal Epidemiology 28 , no. 3 (2014) : 245-254
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Countries
  • Honduras
Nutritional Problems
  • Stunted

Effective delivery of social and behavior change communication through a Care Group model in a supplementary feeding program

Wilner, L., Suri, D. J., Langlois, B. K., Walton, S. M., Rogers, B. L.. "Effective delivery of social and behavior change communication through a Care Group model in a supplementary feeding program." Journal of Health, Population and Nutrition 36 , no. 34 (2017)
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Malawi
Nutritional Problems
  • MAM

Effectiveness of a lipid-based nutrient supplement (LNS) intervention on pregnancy and birth outcomes in Bangladesh

Dewey, K. G., Mridha, M. K., Matias, S. L., Cummins, J. R., Peerson, J. M., Arnold, C. D., Young, R. T., Vosti, S. A.. "Effectiveness of a lipid-based nutrient supplement (LNS) intervention on pregnancy and birth outcomes in Bangladesh." FANTA III: Food and Nutrition Technical Assistance Report (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Countries
  • Bangladesh
Nutritional Problems
  • Pregnant & Lactating Women

Effectiveness of a nutritional program based upon a ready-to-use therapeutic food in Chad

Clavier-Rogez, S., Rogez, J. B., Labrin, L., Branger, B., Dabadie, A.. "Effectiveness of a nutritional program based upon a ready-to-use therapeutic food in Chad." Archives de Pédiatrie: organe officiel de la Sociéte française de pédiatrie 22 , no. 12 (2015) : 1247-1255
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Innovation
Countries
  • Chad
Nutritional Problems
  • SAM

Effectiveness of complementary food supplements and dietary counselling on anaemia and stunting in children aged 6–23 months in poor areas of Qinghai Province, China: a controlled interventional study

Zhang, Y., Wu, Q., Wang, W., Velthoven, M. H., Chang, H., Han, H., Xing, M., Chen, L., Scherpbier, R. W.. "Effectiveness of complementary food supplements and dietary counselling on anaemia and stunting in children aged 6–23 months in poor areas of Qinghai Province, China: a controlled interventional study." BMJ Open 6 , no. 10 (2016)
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
Countries
  • China
Nutritional Problems
  • Stunted

Effectiveness of complementary food supplements and dietary counselling on anaemia and stunting in children aged 6–23 months in poor areas of Qinghai Province, China: a controlled interventional study

Zhang, Y., Wu, Q., Wang, W., van Velthoven, M. H., Chang, Z., Han, H., Xing, M., Chen, L., Scherpbier, R. W.. "Effectiveness of complementary food supplements and dietary counselling on anaemia and stunting in children aged 6–23 months in poor areas of Qinghai Province, China: a controlled interventional study." BMJ Open 6 , no. e011234 (2016)
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
Countries
  • China
Nutritional Problems
  • Stunted

Effectiveness of indigenous ready-to-use therapeutic food in community-based management of uncomplicated severe acute malnutrition: a randomized controlled trial from India

Shewade, H. D., Patro, B. K., Bharti, B., Soundappan, K., Kaur, A., Taneja, N.. "Effectiveness of indigenous ready-to-use therapeutic food in community-based management of uncomplicated severe acute malnutrition: a randomized controlled trial from India." Journal of Tropical Pediatrics 59 , no. 5 (2013) : 393-8
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • India
Nutritional Problems
  • SAM

Effectiveness of milk whey protein-based ready-to-use therapeutic food in treatment of severe acute malnutrition in Malawian under-5 children: a randomised, double-blind, controlled non-inferiority clinical trial

Bahwere, P., Banda, T., Sadler, K., Nyirenda, G., Owino, V., Shaba, B., Dibari, F., Collins, S.. "Effectiveness of milk whey protein-based ready-to-use therapeutic food in treatment of severe acute malnutrition in Malawian under-5 children: a randomised, double-blind, controlled non-inferiority clinical trial." Maternal & Child Nutrition 10 , no. 3 (2014) : 436-451
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Countries
  • Malawi
Nutritional Problems
  • SAM

Effectiveness of nutritional supplementation (RUTF and multi micronutrient) in preventing malnutrition and morbidity in children 6-59 months with infection

van der Kam, S., Roll, S., Salse, N., Jiya, N. M., Swarthout, T. D., Matsumoto, A., Toyoshima, S., Shanks, L.. "Effectiveness of nutritional supplementation (RUTF and multi micronutrient) in preventing malnutrition and morbidity in children 6-59 months with infection." MSF Field Research (2014)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient products (MNP)
Research Gaps
  • Acceptability
  • Effectiveness
  • Use
Countries
  • Nigeria
Nutritional Problems
  • GAM

Effectiveness of three commonly used transition phase diets in the inpatient management of children with severe acute malnutrition: a pilot randomized controlled trial in Malawi

Versloot, C. J., Voskuijl, W., van Vliet, S. J., van den Heuvel, M., Carter, J. C., Phiri, A., Kerac, M., Heikens, G. T., van Rheenen, P. F., Bandsma, R. H. J.. "Effectiveness of three commonly used transition phase diets in the inpatient management of children with severe acute malnutrition: a pilot randomized controlled trial in Malawi." BMC Pediatrics 17 , no. 112 (2017)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Malawi
Nutritional Problems
  • SAM

Effectiveness study for the development of a home fortification programme for young children in Zambia - endline report

Daly, Z., Northrup-Lyons, M., Reid, R., Cheung, M., Hutchinson, D.. "Effectiveness study for the development of a home fortification programme for young children in Zambia - endline report." (2017)
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
Countries
  • Zambia
Nutritional Problems
  • Stunted