Published Studies

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!



Effects of a lipid-based nutrient supplement during pregnancy and lactation on maternal plasma fatty acid status and lipid profile: Results of two randomized controlled trials

Oaks, B. M., Young, R. R., Adu-Afarwuah, S., Ashorn, U., Jackson, K. H., Lartey, A., Maleta, K., Okronipa, H., Sadalaki, J., Baldiviez, L. M., Shahab-Ferdows, S., Ashorn, P., Dewey, K. G.. "Effects of a lipid-based nutrient supplement during pregnancy and lactation on maternal plasma fatty acid status and lipid profile: Results of two randomized controlled trials." Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 117 (2017) : 28-35
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient products (MNP)
Countries
  • Malawi
  • Ghana
Nutritional Problems
  • Stunted

Effects of an intervention on infant growth and development: evidence for different mechanisms at work

Prado, E. L., Abbeddou, S., Yakes Jimenez, E., Somé, J. W., Dewey, K. G., Brown, K. H., Hess, S. Y.. "Effects of an intervention on infant growth and development: evidence for different mechanisms at work." Maternal & Child Nutrition (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Burkina Faso
Nutritional Problems
  • Stunted

Effects of animal source food and micronutrient fortification in complementary food products on body composition, iron status, and linear growth: A randomized trial in Cambodia

Skau, J. K. H., Touch, B., Chhoun, C., Chea, M., Unni, U. S., Makurat, J., Filteau, S., Wieringa, F. T., Dijkhuizen, M. A., Ritz, C., Wells, J. C., Berger, J., Friis, H., Michaelsen, K. F., Roos, N.. "Effects of animal source food and micronutrient fortification in complementary food products on body composition, iron status, and linear growth: A randomized trial in Cambodia." The American Journal of Clinical Nutrition 101 , no. 4 (2015) : 742-751
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Countries
  • Cambodia
Nutritional Problems
  • Stunted

Effects of community-based follow-up care in managing severely underweight children

Hossain, M. I., Nahar, B., Hamadani, J. D., Ahmed, T., Brown, K. H.. "Effects of community-based follow-up care in managing severely underweight children." Journal of Pediatric Gastroenterology and Nutrition 53 , no. 3 (2011) : 310-319
Study Interventions
  • Fortified blended foods (FBF)
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Bangladesh
Nutritional Problems
  • SAM

Effects of community-based sales of micronutrient powders on morbidity episodes in preschool children in Western Kenya

Suchdev, P. S., Addo, O. Y., Martorell, R., Grant, F. K. E., Ruth, L. J., Patel, M. K., Juliao, P. C., Quick, R., Flores-Ayala, R.. "Effects of community-based sales of micronutrient powders on morbidity episodes in preschool children in Western Kenya." American Journal of Clinical Nutrition 103 , no. 3 (2016) : 934-941
Study Interventions
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Kenya
Nutritional Problems
  • Stunted

Effects of maternal and child lipid-based nutrient supplements on infant development: a randomized trial in Malawi

Prado, E. L., Maleta, K., Ashorn, P., Ashorn, U., Vosti, S. A., Sadalaki, J., Dewey, K. G.. "Effects of maternal and child lipid-based nutrient supplements on infant development: a randomized trial in Malawi." American Journal of Clinical Nutrition 103 , no. 3 (2016) : 784-793
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Malawi
Nutritional Problems
  • Stunted

Effects of pre- and post-natal lipid-based nutrient supplements on infant development in a randomized trial in Ghana

Prado, E. L., Adu-Afarwuah, S., Lartey, A., Ocansey, M., Ashorn, P., Vosti, S. A., Dewey, K. G.. "Effects of pre- and post-natal lipid-based nutrient supplements on infant development in a randomized trial in Ghana." Early Human Development 99 (2016) : 43-51
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
Countries
  • Ghana
Nutritional Problems
  • Stunted
  • Pregnant & Lactating Women

Effects of responsive stimulation and nutrition interventions on children's development and growth at age 4 years in a disadvantaged population in Pakistan: A longitudinal follow-up of a cluster-randomised factorial effectiveness trial

Yousafzai, A. K., Obradović, J., Rashee, M. A., Rizvi, A., Portilla, X. A., Tirado-Strayer, N., Siyal, S., Memon, U.. "Effects of responsive stimulation and nutrition interventions on children's development and growth at age 4 years in a disadvantaged population in Pakistan: A longitudinal follow-up of a cluster-randomised factorial effectiveness trial." The Lancet Global Health 4 , no. 8 (2016) : e548-e558
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient products (MNP)
Research Gaps
  • Effectiveness
Countries
  • Pakistan
Nutritional Problems
  • Stunted

Effects of small-quantity lipid-based nutrient supplement on hemoglobin and iron status of pregnant Ghanaian women

Adu-Afarwuah, S., Lartey, A., Okronipa, H., Peerson, J., Ashorn, P., Dewey, K.. "Effects of small-quantity lipid-based nutrient supplement on hemoglobin and iron status of pregnant Ghanaian women." The FASEB Journal 29 , no. 1_Supplement (2015) : 39.5-
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient products (MNP)
Research Gaps
  • Composition
  • Effectiveness
Countries
  • Ghana
Nutritional Problems
  • Pregnant & Lactating Women

Effects of unconditional cash transfers on the outcome of treatment for severe acute malnutrition (SAM): a cluster-randomised trial in the Democratic Republic of the Congo  

Grellety, E., Babakazo, P., Bangana, A., Mwamba, G., Lezama, I., Zagre, N. M., Ategbo, E-A.. "Effects of unconditional cash transfers on the outcome of treatment for severe acute malnutrition (SAM): a cluster-randomised trial in the Democratic Republic of the Congo  ." BMC Medicine 15 , no. 87 (2017)
Study Interventions
  • Cash transfer
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • Democratic Republic of the Congo
Nutritional Problems
  • SAM

Efficacy of iron-supplement bars to reduce anemia in urban Indian women: a cluster-randomized controlled trial

Mehta, R., Platt, A. C., Sun, X., Desai, M., Clements, D., Turner, E. L.. "Efficacy of iron-supplement bars to reduce anemia in urban Indian women: a cluster-randomized controlled trial." The American Journal of Clinical Nutrition (2017)
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
Countries
  • India
Nutritional Problems
  • Stunted

Efficacy of sorghum peanut blend and corn soy blend plus in the treatment of moderate acute malnutrition in children aged 6–59 months in Karamoja, Uganda: a cluster randomized trial

Amegovu, Andrew Kiri, Ochola, Sophie, Ogwok, Patrick, Yiga, Peter, Musalima, Juliet, Juliana, Mandha. "Efficacy of sorghum peanut blend and corn soy blend plus in the treatment of moderate acute malnutrition in children aged 6–59 months in Karamoja, Uganda: a cluster randomized trial." Nutrition & Dietary Supplements 6 (2014) : 75-84
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Innovation
Countries
  • Uganda
Nutritional Problems
  • MAM

Efficacy of three feeding regimens for home-based management of children with uncomplicated severe acute malnutrition: a randomised trial in India

Bhandari, N., Mohan, S. B., Bose, A., Iyengar, S. D., Taneja, S., Mazumder, S., Pricilla, R. A., Iyengar, K., Sachdev, H. S., Mohan, V. R., Suhalka, V., Yoshida, S., Martines, J., Bahl, R.. "Efficacy of three feeding regimens for home-based management of children with uncomplicated severe acute malnutrition: a randomised trial in India." BMJ Global Health 1 , no. e000144 (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Other
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Countries
  • India
Nutritional Problems
  • SAM

Energy and nutrient intake increased by 47–67% when amylase was added to fortified blended foods—a study among 12- to 35-month-old Burkinabe children

Kampstra, N. A., Van Hoan, N., Koenders, D. J. P. C., Schoop, R., Broersen, C. B., Mouquet-Rivier, C., Traore, T., Bruins, M. J., de Pee, S.. "Energy and nutrient intake increased by 47–67% when amylase was added to fortified blended foods—a study among 12- to 35-month-old Burkinabe children." Maternal & Child Nutrition (2017)
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Acceptability
  • Composition
Countries
  • Burkina Faso
Nutritional Problems
  • Stunted
  • GAM

Enhancements to nutrition program in Indian Integrated Child Development Services increased growth and energy intake of children

Avula, R., Frongillo, E. A., Arabi, M., Sharma, S., Schultink, W.. "Enhancements to nutrition program in Indian Integrated Child Development Services increased growth and energy intake of children." The Journal of Nutrition 141 (2011) : 680-684
Study Interventions
  • Locally produced
  • Micronutrient products (MNP)
  • Other
Research Gaps
  • Effectiveness
  • Innovation
Countries
  • India
Nutritional Problems
  • Stunted
  • GAM