Comparison of a locally produced RUTF with a commercial RUTF in the treatment of SAM (FLNS_SAM)

Primary Investigator

  • Frank Wieringa

Study Period

April 2016 - December 2016

Study Description

In order to make Cambodia independent from importing a product for the treatment and prevention of malnutrition, UNICEF, DFPTQ Fisheries Administration and IRD have started a collaboration for the development of a range of products for the treatment and prevention of malnutrition. To reduce costs of the product, and to adapt the taste to local circumstances, the protein source of the usual RUTF (milk powder) has been changed to fish (Trey Riel). The main objective of this sub-study is to test the efficacy of the newly developed RUTF on the recovery of children suffering from severe acute malnutrition. As comparison, the current treatment of SAM with BP-100 will be used.

Study Arms

  • Active Comparator: BP-100: standard 2 months of treatment
  • Experimental: Num Trey: 2 months of treatment with locally produced RUTF

Primary Outcomes

  • weight gain (WHZ) in 2 months

Study Interventions

  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced

Research Gaps

  • Acceptability

    Which food products do recipients enjoy eating and have the fewest side effects?

  • Composition

    Which ingredients offer the best prevention or treatment for undernutrition?

  • Effectiveness

    How well do different food compositions and interventions prevent or treat undernutrition, when implemented "on the ground"?

  • Innovation

    What novel food-based products and programming methods effectively prevent and treat undernutrition?

Study Population

120