Effect Of A Biofortified Food Basket On Micronutrient Status And Immune And Cognitive Function Among Infants In India

Primary Investigators

  • Bonam Wesley
  • Jere Haas
  • Julia Finkelstein
  • Shobha Udipi

Study Period

February 2019 - December 2020

Study Description

Brief Summary:
In this study, a multiple food crops basket (containing four either biofortified or commercially-available food crops) will be fed to young children in Madanapalle, Andhra Pradesh, India over a period of nine months to measure growth, cognitive changes, and immune function in comparison to children receiving non-biofortified crops. Lactating women (their mothers) will also be included in the study.

Study Arms

  • Experimental: MBFC-Exp The MBFC-Exp (four biofortified food crops - Experimental) arm will consume the biofortified multiple food crops basket.
  • Active Comparator: MBFC-C The MBFC-C (Multiple biofortified food crops - Control) arm will consume the non-biofortified (commercially available) four food crops basket.

Primary Outcomes

  • Biomarkers of vitamin A, iron, and zinc status [ Time Frame: endline (9 months) ]
  • Physical growth [ Time Frame: endline (9 months) ]
  • Immune function [ Time Frame: endline (9 months) ]
  • Cognitive function [ Time Frame: endline (9 months) ]

Study Interventions

  • Other
  • Locally produced

Research Gaps

  • Acceptability

    Which food products do recipients enjoy eating and have the fewest side effects?

  • Effectiveness

    How well do different food compositions and interventions prevent or treat undernutrition, when implemented "on the ground"?

  • Innovation

    What novel food-based products and programming methods effectively prevent and treat undernutrition?

Study Population

400