Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 33 Results
Katherine P. Adams, Seth Adu‐Afarwuah, Malay K. Mridha, Brietta M. Oaks, Susana L. Matias, Charles D. Arnold, Sika M. Kumordzie, Charles D. Arnold, Harriet Okronipa, Maku E. Ocansey, Kathryn G. Dewey. "." (2020)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Ayse Ercumen ,Jade Benjamin-Chung ,Benjamin F. Arnold,Audrie Lin,Alan E. Hubbard, Christine Stewart, Zahidur Rahman, Sarker Masud Parvez, Leanne Unicomb, Mahbubur Rahman, Rashidul Haque, John M. Colford Jr., and Stephen P. Luby. "." PLoS Neglected Tropical Diseases 13 , no. 5 (2019)
Study Interventions
  • Water, sanitation, hygiene (WASH)
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Julie M Long, Prasenjit Mondal, Jamie E Westcott, Leland V Miller, M Munirul Islam, Mondar Ahmed, Mustafa Mahfuz, Tahmeed Ahmed, Nancy F Krebs.. "." Journal of Nutrition 149 , no. 1 (2019) : 98–105
Study Interventions
  • Standard Fortified Food Blends
  • Environmental enteric dysfunction (EED)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Md. Iqbal Hossain, Sayeeda Huq, M. Munirul Islam, Tahmeed Ahmed.. "." European Journal of Nutrition (2019)
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Briony Stevens, Kerrianne Watt, Julie Brimbecombe, Alan Clough, Jenni A. Judd, and Daniel Lindsay. "   ." BMC Pregnancy & Childbirth 18 (2018) : 286
Study Interventions
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Audrie Lin , Benjamin F Arnold, Andrew N Mertens, Jue Lin, Jade Benjamin-Chung, Shahjahan Ali, Alan E Hubbard, Christine P Stewart, Abul K Shoab, Md Ziaur Rahman, Md Saheen Hossen, Palash Mutsuddi, Syeda L Famida, Salma Akther, Mahbubur Rahman, Leanne Unic. "." eLife 6 (2017)
Study Interventions
  • Water, sanitation, hygiene (WASH)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Pernilla Svefors , Katarina Ekholm Selling, Rubina Shaheen, Ashraful Islam Khan, Lars-Åke Persson, Lars Lindholm. "." PLoS ONE 13 , no. 2 (2018)
Study Interventions
  • Other
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Humber, J., Vosti, S. A., Cummins, J., Mridha, M., Matias, S. L., Dewey, K.. "The Rang-Din Nutrition Study in rural Bangladesh: the costs and cost-effectiveness of programmatic interventions to improve linear growth at birth and 18 months, and the costs of these interventions at 24 months ." FANTA III Food and Nutrition Technical Assistance Report (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Harding, K. L., Matias, S. L., Moniruzzaman, M., Stewart, C. P., Mridha, M. K., Vosti, S. A., Dewey, K. G.. "Rang-Din Nutrition Study: Assessment of participant adherence to lipid-based nutrient and iron-folic acid supplements among pregnant and lactating women in the context of a study on the effectiveness of supplements in Bangladesh ." FANTA III Food and Nutrition Technical Assistance Report (2014)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Harding, K. L., Matias, S. L., Moniruzzaman, M., Mridha, M. K., Vosti, S. A., Dewey, K. G.. "Rang-Din Nutrition Study: assessment of adherence to lipid-based nutrient supplements and micronutrient powders among children 6-23 months in Bangladesh ." FANTA III Food and Nutrition Technical Assistance Report (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Dewey, K. G., Mridha, M. K., Matias, S. L., Cummins, J. R., Peerson, J. M., Arnold, C. D., Young, R. T., Vosti, S. A.. "Effectiveness of a lipid-based nutrient supplement (LNS) intervention on pregnancy and birth outcomes in Bangladesh ." FANTA III: Food and Nutrition Technical Assistance Report (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Ziauddin Hyder, S. M., Haseen, F., Rahman, M., Tondeur, M. C., Zlotkin, S. H.. "Effect of daily versus once-weekly home fortification with micronutrient Sprinkles on hemoglobin and iron status among young children in rural Bangladesh ." Food and Nutrition Bulletin 28 , no. 7 (2007)
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Adams, A. M., Ahmed, R., Mahbub Latif, A. H. M., Rasheed, S., Das, S. K., Hasib, E., Farzana, F. D., Ferdous, F., Ahmed, S., Faruque, A. S. G.. "Impact of fortified biscuits on micronutrient deficiencies among primary school children in Bangladesh ." PLoS One (2017)
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Stevens, B., Watt, K., Brimblecombe, J., Clough, A., Judd, J.. "Development of a locally produced, balanced protein-energy food-based supplement and its acceptance by undernourished pregnant women in Northern Bangladesh ." Journal of Hunger & Environmental Nutrition (2016) : 100-115
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Dewey, K. G., Mridha, M. K., Matias, S. L., Arnold, C. D., Cummins, J. R., Khan, M. S. A., Maalouf-Manasseh, Z., Siddiqui, Z., Ullah, B. "Lipid-based nutrient supplementation in the first 1000 d improves child growth in Bangladesh: a cluster-randomized effectiveness trial ." The American Journal of Clinical Nutrition (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Nisbett, N., Longhurst, R., Barnett, I., Feruglio, F., Gordon, J., Hoddinott, J., Jahan, F., Karachiwalla, N., Roy, S., Shah, V., Siddiki, O. F., Tranchant, J. P., White, J.. "Impact evaluation of the DFID Programme to accelerate improved nutrition for the extreme poor in Bangladesh: Final Report ." DFID (2016)
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Rahman, A. S., Ahmed, T., Ahmed, F., Alam, M. S., Wahed, M. A., Sack, D. A.. "Double-blind cluster randomised controlled trial of wheat flour chapatti fortified with micronutrients on the status of vitamin A and iron in school-aged children in rural Bangladesh ." Maternal & Child Nutrition 11 , no. S4 (2015) : 120-131
Study Interventions
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Choudhury, N., Bromage, S., Alam, M. A., Shamsir Ahmed, A. M., Munirul Islam, M., Iqbal Hossain, M., Mahfuz, M., Mondal, D., Ahmed, T.. "Intervention study shows suboptimal growth among children receiving a food supplement for five months in a slum in Bangladesh ." Acta Paediatrica 105 , no. 10 (2016) : e464-e473
Study Interventions
  • Standard Fortified Food Blends
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Shamim, A. A., Hanif, Abu A. M., Merrill, R. D., Campbell, R. K., Kumkum, M. A., Shaikh, S., de Pee, S., Ahmed, T., Parveen, M., Mehra, S., Klemm, R. D. W., Labrique, A. B., West, K. P., Christian, P.. "Preferred delivery method and acceptability of Wheat-Soy Blend (WSB++) as a daily complementary food supplement in northwest Bangladesh     ." Ecology of Food and Nutrition 54 , no. 1 (2015) : 74-92
Study Interventions
  • Standard Fortified Food Blends
  • Animal-source protein
Research Gaps
  • Acceptability
  • Innovation
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Subramanian, S., Huq, S., Yatsunenko, T., Haque, R., Mahfuz, M., Alam, M. A., Benezra, A., DeStefano, J., Meier, M. F., Muegge, B. D., Barratt, M. J., VanArendonk, L. G., Zhang, Q., Province, M. A., Petri, W. A., Ahmed, T., Gordon, J. I.. "Persistent gut microbiota immaturity in malnourished Bangladeshi children ." Nature 510 , no. 7505 (2014) : 417-21
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Environmental enteric dysfunction (EED)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Ali, E., Zachariah, R., Shams, Z., Manzi, M., Akter, T., Alders, P., Allaouna, M., Delchevalerie, P., Harries, A. D.. "Peanut-based ready-to-use therapeutic food: How acceptable and tolerated is it among malnourished pregnant and lactating women in Bangladesh? ." Maternal & Child Nutrition 11 , no. 4 (2015) : 1028-1035
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Ali, E., Zachariah, R., Dahmane, A., Van den Boogaard, W., Shams, Z., Akter, T., Alders, P., Manzi, M., Allaouna, M., Draguez, B., Delchevalerie, P., Harries, A. D.. "Peanut-based ready-to-use therapeutic food: acceptability among malnourished children and community workers in Bangladesh ." Public Health Action 3 , no. 2 (2013) : 128-135
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Sethuraman, K., Doledec, D., Begum, F., Manir, M. Z.. "Managing acute malnutrition: A review of the evidence and country experiences in South Asia and a recommended approach for Bangladesh ." FANTA Project (2014)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
  • Animal-source protein
Research Gaps
  • Effectiveness
  • Efficacy
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Mridha, M. K., Matias, S. L., Chaparro, C. M., Paul, R. R., Hussain, S., Vosti, S. A., Harding, K. L., Cummins, J. R., Day, L. T., Saha, S. L., Peerson, J. M., Dewey, K. G.. "Lipid-based nutrient supplements for pregnant women reduce newborn stunting in a cluster-randomized controlled effectiveness trial in Bangladesh ." The American of Clinical Nutrition 103 , no. 1 (2016) : 236-49
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Caulfield, L. E., Huffman, S. L., Piwoz, E. G.. "." Food and Nutrition Bulletin 2 , no. 2 (1999) : 183-200
Study Interventions
  • Standard Fortified Food Blends
  • Behavior change communication (BCC)
Research Gaps
  • Effectiveness
  • Efficacy
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight