Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 123 Results
Natasha Lelijveld, Claire Godbout, Destiny Krietemeyer, Alyssa Los, Donna Wegner, David T Hendrixson, Robert Bandsma, Aminata Koroma, Mark Manary. "." The American Journal of Clinical Nutrition (2021) : nqab137
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Behavior change communication (BCC)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Xuejing Li, Yan Hui, Bingfeng Leng, Junli Ren, Yanni Song, Lianqiang Che, Xi Peng, Baojia Huang, Songling Liu, Lin Li, Dennis Sandris Nielsen, Yong Li, Xiaoshuang Dai, Shancen Zhao. "." PLoS One 16 , no. 4 (2021) : e0250423.
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Stacy P Griswold, Breanne K Langlois, Ye Shen, Ilana R Cliffer, Devika J Suri, Shelley Walton, Ken Chui, Irwin H Rosenberg, Aminata S Koroma, Donna Wegner. "." The American Journal of Clinical Nutrition (2021)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Cost
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Devika J Suri, Isabel Potani, Akriti Singh, Stacy Griswold, William W Wong, Breanne Langlois, Ye Shen, Kwan Ho Kenneth Chui, Irwin H Rosenberg, Patrick Webb, Beatrice L Rogers. "." The Journal of Nutrition. (2021) : nxab080
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Akriti Singh. "." The American Journal of Clinical Nutrition (2021)
Study Interventions
  • Environmental enteric dysfunction (EED)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Natasha Lelijveld, Eunice Musyoki, Susan Were Adongo, Amy Mayberry, Jonathan C. Wells, Charles Opondo, Marko Kerac, Jeanette Bailey. "." PLoS ONE 16 , no. 2 (2021) : e0245477
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition
Jef L Leroy, Deanna K Olney, Noé Nduwabike, Marie T Ruel. "." The Journal of Nutrition 151 , no. 1 (2021) : 197–205
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Behavior change communication (BCC)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Cécile Cazes, Kevin Phelan, Victoire Hubert, Rodrigue Alitanou, Harouna Boubacar, Liévin Izie Bozama, Gilbert Tshibangu Sakubu, Aurélie Beuscart, Cyrille Yao, Delphine Gabillard, Moumouni Kinda, Augustin Augier, Xavier Anglaret. "." BMJ Open 10 (2020) : e041213
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition
Mette F. Olsen, Ann-Sophie Iuel-Brockdorff, Charles W. Yaméogo, Bernardette Cichon, Christian Fabiansen, Suzanne Filteau, Kevin Phelan, Albertine Ouédraogo, Kim F. Michaelsen, Melissa Gladstone, Per Ashorn, André Briend, Christian Ritz, Henrik Friis, Vibeke B. Christ. "." PLoS medicine 17 , no. 12 (2020) : e1003442
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Animal-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Harriet Okronipa, Amado D Quezada-Sánchez, Susan L Johnson, Cloe Rawlinson, Selene Pacheco-Miranda, Mónica Venosa López, Anabelle Bonvecchio Arenas, Wendy Gonzalez Navarrete. "." Nutrients 12 , no. 10 (2020) : 3069
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Acceptability
  • Composition
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Parul Christian, Kristen M Hurley, John Phuka, Yunhee Kang, Julie Ruel-Bergeron, Audrey J Buckland, Maithilee Mitra, Lee Wu, Rolf Klemm, Keith P West, Jr. "." The Journal of Nutrition (2020)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Behavior change communication (BCC)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Gul Nawaz Khan, Sumra Kureishy, Shabina Ariff, Arjumand Rizvi, Muhammad Sajid, Cecilia Garzon, Ali Ahmad Khan, Saskia de Pee, Sajid Bashir Soofi, Zulfiqar A. Bhutta. "." PloS one 15 , no. 8 (2020) : p.e0237210
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Azimi F, Esmaillzadeh A, Alipoor E, Moslemi M, Yaseri M, Hosseinzadeh-Attar MJ. "." Public Health , no. 185 (2020) : 290-297
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Composition
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Susan B Roberts, Maria A Franceschini, Rachel E Silver, Salima F Taylor, Augusto Braima de Sa, Raimundo Có, Aliu Sonco, Amy Krauss, Patrick Webb , Amy Taetzsch, Sai Krupa Das, C-Y Chen, Beatrice L Rogers, Edward Saltzman, Pei-Yi Lin, Nina Schlossman, William Pruzensky, Carlito Balé, Kenneth Kwan Ho Chui, Paul Muentener. "." BMJ (2020) : 370
Study Interventions
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Maren J. H. Rytter, Bernardette Cichon, Christian Fabiansen, Charles W. Yameogo, Sylvain Z. Windinmi, Kim F. Michaelsen, Suzanne Filteau, Dorthe L. Jeppesen, Henrik Friis, André Briend, Vibeke B. Christensen . "." Pediatric Research (2020) : 1-10
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Jeanette Bailey. "." PLoS Med 17 , no. 7 (2020) : e1003192
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Cost
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Meghan Callaghan, Momo Oyama, Mark Manary. "." The Journal of Nutrition 147 , no. 3 (2020) : 277–280
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Rebecca Roediger, Hans-Henrik Stein, Meghan Callaghan-Gillespie , Jeffrey Kahn Blackman, Kristin Kohlmann, Kenneth Maleta, Mark Manary. "." Maternal & Child Nutrition , no. e13019 (2020)
Study Interventions
  • Animal-source protein
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Caroline Marquer, Céline Langendorf, Lynda Christelle Woi-Messe, Fatou Berthe, Eric-Alain Ategbo, Santiago Rodas-Moya, Saskia dePee,, and Rebecca F. Grais. "." BMC Nutrition 6 , no. 1 (2020) : 1-8
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Ye Shen, Ilana R. Cliffer, Devika J. Suri, Breanne K. Langlois, Stephen A. Vosti, Patrick Webb, Beatrice L. Rogers. "." Nutrition Journal 19 , no. 1 (2020) : 1-18
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Ilana R Cliffer, Laetitia Nikiema, Breanne K Langlois, Augustin N Zeba, Ye Shen, Hermann B Lanou, Devika J Suri, Franck Garanet, Kenneth Chui, Stephen Vosti, Shelley Walton, Irwin Rosenberg, Patrick Webb, Beatrice L Rogers. "." Current Developments in Nutrition 4 , no. 2 (2020)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Mark Manary, Meghan Callaghan-Gillespie. "." Global Landscape of Nutrition Challenges in Infants and Children 93 (2020) : 111-120
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Cost
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
  • Treatment of Moderate Acute Malnutrition
Breanne K Langlois, Ilana R Cliffer, Laetitia Nikiema, Devika J Suri, Franck Garanet, Ye Shen, Augustin N Zeba, Shelley M Walton, Hermann B Lanou, Patrick Webb, and Beatrice L Rogers. "." Current Developments in Nutrition 4 , no. 2 (2020)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Seth Adu-Afarwuah, Rebecca R Young, Anna Lartey, Harriet Okronipa, Per Ashorn, Ulla Ashorn, Brietta M Oaks, Kathryn G Dewey. "." Journal of Nutrition (2019) : nxz243
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition
Lieven Huybregts , Agnes Le Port, Elodie Becquey, Amanda Zongrone, Francisco M. Barba, Rahul Rawat, Jef L. Leroy, and Marie T. Ruel. "." PLoS Medicine 16 , no. 8 (2019)
Study Interventions
  • Water, sanitation, hygiene (WASH)
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Behavior change communication (BCC)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition