Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 76 Results
Marius Affonfere, Flora Josiane Chadare, Finagnon Toyi Kévin Fassinou, Elise F. Talsma, Anita R. Linnemann, Paulin Azokpota. "." Food Science & Nutrition (2021)
Study Interventions
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Acceptability
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Theresa Banda, Khataza Chawanda, Wakako Tsuchida, Slyvester Kathumba. "." Food and Nutrition Bulletin 42 , no. 1 (2021) : 91-103
Study Interventions
  • Plant-source protein
  • Experimental Lipid Based Nutrients
Research Gaps
  • Composition
  • Efficacy
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Harriet Okronipa, Amado D Quezada-Sánchez, Susan L Johnson, Cloe Rawlinson, Selene Pacheco-Miranda, Mónica Venosa López, Anabelle Bonvecchio Arenas, Wendy Gonzalez Navarrete. "." Nutrients 12 , no. 10 (2020) : 3069
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Acceptability
  • Composition
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Azimi F, Esmaillzadeh A, Alipoor E, Moslemi M, Yaseri M, Hosseinzadeh-Attar MJ. "." Public Health , no. 185 (2020) : 290-297
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Composition
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Rachel S. Bergmans, Maria Nikodemova, Valerie J. Stull, Ashley Rapp, Kristen M. C. Malecki. "." Plos ONE 15 , no. 6 (2020) : p.fiaa105.
Study Interventions
  • Animal-source protein
Research Gaps
  • Composition
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Meghan Callaghan, Momo Oyama, Mark Manary. "." The Journal of Nutrition 147 , no. 3 (2020) : 277–280
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Rebecca Roediger, Hans-Henrik Stein, Meghan Callaghan-Gillespie , Jeffrey Kahn Blackman, Kristin Kohlmann, Kenneth Maleta, Mark Manary. "." Maternal & Child Nutrition , no. e13019 (2020)
Study Interventions
  • Animal-source protein
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
David Taylor Hendrixson, Claire Godbout, Alyssa Los, Meghan Callaghan-Gillespie, Melody Mui, Donna Wegner, Taylor Bryant, Aminata Koroma, Mark J Manary. "." Gut (2020)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Rosalie H. Bartels, Emmanuel Chimwezi, Victoria Watson, Leilei Pei, Isabel Potani, Benjamin Allubha, Kate Chidzalo, Duolao Wang, Queen Dube, Macpherson Mallewa, Angela Allen, Robert H. J. Bandsma, Wieger P. Voskuijl and Stephen J. Allen . "." Scientific Reports, Nature Publishing 9 , no. 1 (2019)
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
R. B. Kajjura, F. J. Veldman, S. M. Kassier. "." Journal of Human Nutrition and Dietetics 32 , no. 3 (2019) : 295–302
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Sarah J Zyba, Rita Wegmüller, Leslie R Woodhouse, Kabiru Ceesay, Andrew M Prentice, Kenneth H Brown, and K Ryan Wessells. "." The American Journal of Clinical Nutrition 110 , no. 6 (2019) : 1465–1475
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition
Mangani C, Maleta K, Phuka J, Cheung YB, Thakwalakwa C, Dewey K, Manary M, Puumalainen T, Ashorn P.. "." Maternal & Child Nutrition 11 , no. S4 (2015) : 132-143
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Julie M Long, Prasenjit Mondal, Jamie E Westcott, Leland V Miller, M Munirul Islam, Mondar Ahmed, Mustafa Mahfuz, Tahmeed Ahmed, Nancy F Krebs.. "." Journal of Nutrition 149 , no. 1 (2019) : 98–105
Study Interventions
  • Standard Fortified Food Blends
  • Environmental enteric dysfunction (EED)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Gladstone MJ, Chandna J, Kandawasvika G, Ntozini R, Majo FD, Tavengwa NV, Mbuya MNN, Mangwadu GT, Chigumira A, Chasokela CM, Moulton LH, Stoltzfus RJ, Humphrey JH, Prendergast AJ; SHINE Trial Team.. "." PLoS Medicine 16 , no. 3 (2019)
Study Interventions
  • Water, sanitation, hygiene (WASH)
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Humphrey JH, Mbuya MNN, Ntozini R, Moulton LH, Stoltzfus RJ, Tavengwa NV, Mutasa K, Majo F, Mutasa B, Mangwadu G, Chasokela CM, Chigumira A, Chasekwa B, Smith LE, Tielsch JM, Jones AD, Manges AR, Maluccio JA, Prendergast AJ; SHINE Team. "." Lancet Global Health 7 , no. 1 (2019) : e132-e147
Study Interventions
  • Water, sanitation, hygiene (WASH)
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
McDonald CM, Ackatia-Armah RS, Doumbia S, Kupka R, Duggan CP, Brown KH. "." The Journal of Nutrition 149 , no. 6 (2019) : 1089–1096
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Robert H. J. Bandsma , Wieger Voskuijl, Emmanuel Chimwezi, Greg Fegan, André Briend, Johnstone Thitiri, Moses Ngari, Laura Mwalekwa, Victor Bandika, Rehema Ali, Fauzat Hamid, Betty Owor, Neema Mturi, James A. Berkley. "     ." PLoS Medicine 2 , no. 16 (2019)
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Agapova, S. E., Stephenson, K. B., Divala, O., Kaimila, Y., Maleta K. M., Thakwalakwa, C., Ordiz, M. I., Trehan, I., Manary, M. J.. "." 148 , no. 2 (2018) : 267–274
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Kevin B Stephenson, Sophia E Agapova, Oscar Divala, Yankho Kaimila, Kenneth M Maleta, Chrissie Thakwalakwa, M Isabel Ordiz, Indi Trehan, Mark J Manary. "." American Journal of Clinical Nutrition 106 , no. 6 (2017) : 1500-1507
Study Interventions
  • Standard Fortified Food Blends
  • Environmental enteric dysfunction (EED)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Christian Fabiansen, Kevin PQ Phelan, Bernardette Cichon, Christian Ritz, André Briend, Kim F Michaelsen, Henrik Friis, Susan Shepherd. "." American Journal of Clinical Nutrition 103 , no. 2 (2016) : 415-421
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Elizabeth M. Sloffer, Shashank Gaur, Nicki J. Engeseth, Juan E. Andrade. "." Foods 6 , no. 11 (2017) : 97
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Composition
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition
Dube, B., Rongsen, T., Mazumder, S., Taneja, S., Rafiqui, F., Bhandari, N., Bhan, M. K.. "Comparison of ready-to-use therapeutic food with cereal legume-based Khichri among malnourished children ." Indian Pediatrics 46 (2009) : 383-388
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Acceptability
  • Composition
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Ackatia-Armah, R. S., McDonald, C., Doumbia, S., Brown, K. H.. "Effect of selected dietary regimens on recovery from moderate acute malnutrition in young Malian children ." The FASEB Journal 26 , no. 1 (2012)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Lin, C. A., Manary, M. J., Maleta, K., Briend, A., Ashorn, P.. "An energy-dense complementary food is associated with a modest increase in weight gain when compared with a fortified porridge in Malawian children aged 6–18 months ." Journal of Nutrition 138 (2008) : 593-598
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Isanka, S., Roederer, T., Djibo, A., Luquero, F. J., Nombela, N., Guerin, P. J., Grais, R. F.. "Reducing wasting in young children with preventive supplementation: a cohort study in Niger ." Pediatrics 126 , no. 2 (2010) : e442-450
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight