Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 14 of 14 Results
Owino, V. O., Irena, A. H., Dibari, F., Collins, S.. "Development and acceptability of a novel milk-free soybean-maize-sorghum ready-to-use therapeutic food (SMS-RUTF) based on industrial extrusion cooking process ." Maternal & Child Health 10 , no. 1 (2014) : 126-134
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Locally produced
Research Gaps
  • Acceptability
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Cames, C., Varloteaux, M., Have, N. N., Diom, A. B.,, Msellati, P., Mbaye, N., Mbodji, H., Sy Signate, H., Diack, A., ANRS 12279 MAGGSEN Cohort Study. "Acceptability of outpatient ready-to-use food-based protocols in HIV-infected Senegalese children and adolescents within the MAGGSEN cohort study   ." Food and Nutrition Bulletin 38 , no. 1 (2016) : 27-36
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition
Ali, E., Zachariah, R., Shams, Z., Manzi, M., Akter, T., Alders, P., Allaouna, M., Delchevalerie, P., Harries, A. D.. "Peanut-based ready-to-use therapeutic food: How acceptable and tolerated is it among malnourished pregnant and lactating women in Bangladesh? ." Maternal & Child Nutrition 11 , no. 4 (2015) : 1028-1035
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Ali, E., Zachariah, R., Dahmane, A., Van den Boogaard, W., Shams, Z., Akter, T., Alders, P., Manzi, M., Allaouna, M., Draguez, B., Delchevalerie, P., Harries, A. D.. "Peanut-based ready-to-use therapeutic food: acceptability among malnourished children and community workers in Bangladesh ." Public Health Action 3 , no. 2 (2013) : 128-135
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Ashorn, U., Alho, L., Arimond, M., Dewey, K. G., Maleta, K., Phiri, N., Phuka, J., Vosti, S. A., Zeilani, M., Ashorn, P.. "Malawian mothers consider lipid-based nutrient supplements acceptable for children throughout a 1-year intervention, but deviation from user recommendations is common ." The Journal of Nutrition 145 , no. 7 (2015) : 1588-1595
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Scherbaum, V., Purwestri, R. C., Stuetz, W., Inayati, D. A., Suryantan, J., Bloem, M. A., Biesalski, H. K.. "Locally produced cereal/nut/legume-based biscuits versus peanut/milk-based spread for treatment of moderately to mildly wasted children in daily programmes on Nias Island, Indonesia: an issue of acceptance and compliance? ." Asia Pacific Journal of Clinical Nutrition 24 , no. 1 (2015) : 152
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Other
  • Behavior change communication (BCC)
  • Animal-source protein
Research Gaps
  • Acceptability
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Wang, R. J., Trehan, I., LaGrone, L. N., Weisz, A. J., Thakwalakwa, C. M., Maleta, K. M., Manary, M. J.. "Investigation of food acceptability and feeding practices for lipid nutrient supplements and blended flours used to treat moderate malnutrition ." Journal of Nutrition Education and Behavior 45 , no. 3 (2013) : 258-263
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Zebdewos, A., Singh, P., Birhanu, G., Whiting, S. J., Henry, C. J., Kebebu, A.. "Formulation of complementary food using amaranth, chickpea and maize improves iron, calcium and zinc content ." African Journal of Food, Agriculture, Nutrition and Development 15 , no. 4 (2015) : 10290-10304
Study Interventions
  • Plant-source protein
  • Locally produced
Research Gaps
  • Acceptability
  • Composition
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Iuel-Brockdorf, A. S., Draebel, T. A., Ritz, C., Fabiansen, C., Cichon, B., Brix Christensen, V., Yameogo, C., Oummani, R., Briend, A., Michaelsen, K. F., Ashorn, P., Filteau, S., Friis, H.. "Evaluation of the acceptability of improved supplementary foods for the treatment of moderate acute malnutrition in Burkina Faso using a mixed method approach ." Appetite 99 (2016) : 34-45
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Ahmed, T., Choudhury, N., Hossain, M. I., Tangsuphoom, N., Islam, M. M., de Pee, S., Steiger, G., Fuli, R., Sarker, S. A. M., Parveen, M., West, K. P., Christian, P.. "Development and acceptability testing of ready-to-use supplementary food made from locally available food ingredients in Bangladesh ." BMC Pediatrics 14 , no. 1 (2014) : 164
Study Interventions
  • Plant-source protein
  • Locally produced
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Hess, S. Y., Bado, L., Aaron, G. J., Ouédraogo, J. B., Zeilani, M., Brown, K. H.. "Acceptability of zinc-fortified, lipid-based nutrient supplements (LNS) prepared for young children in Burkina Faso ." Maternal & Child Nutrition 7 , no. 4 (2011) : 357-367
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Phuka, J., Ashorn, U., Ashorn, P., Zeilani, M., Cheung, Y. B., Dewey, K. G., Manary, M., Maleta, K.. "Acceptability of three novel lipid-based nutrient supplements among Malawian infants and their caregivers ." Maternal & Child Nutrition 7 , no. 4 (2011) : 368-377
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Acceptability
  • Composition
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Iuel-Brockdorf, A., Dræbelc, T. A., Fabiansenb, C., Cichon, B., Brix Christensen, V., Yameogob, C., Ritz, C., Frahm Olsen, M., Friis, H.. "Acceptability of new formulations of corn-soy blends and lipid-based nutrient supplements in Province du Passoré, Burkina Faso ." Appetite (2015)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Acceptability
  • Composition
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Adu-Afarwuah, S., Lartey, A., Zeilani, M., Dewey, K. G.. "Acceptability of lipid-based nutrient supplements (LNS) among Ghanaian infants and pregnant or lactating women ." Maternal & Child Nutrition 7 , no. 4 (2011) : 344-56
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight