Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 22 of 22 Results
Stacy P Griswold, Breanne K Langlois, Ye Shen, Ilana R Cliffer, Devika J Suri, Shelley Walton, Ken Chui, Irwin H Rosenberg, Aminata S Koroma, Donna Wegner. "." The American Journal of Clinical Nutrition (2021)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Cost
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Dieynaba S. N'Diaye, Bibata Wassonguema, Victor Nikièma, Suvi T. Kangas, Cécile Salpéteur. "." Maternal & Child Nutrition (2021) : e13118
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Gul Nawaz Khan1, MA, MPH ; 2, MPH ; 1, MBBS, FCPS ; 1, MBBS, PhD ; 3, MBBS ; 3, MBBS ; 1, MA ; 4, MA ; 2, BSc ; Alba Cecilia G, Sumra Kureishy, Shabina Ariff, Muhammad Atif Habib, Asra Abeer Usmani, Areeba Mubarik, Masawar Hussain, Naveed Akbar, Pablo Rodriguez de Castro, Alba Cecilia Garzon, Saskia de Pee, Sajid Bashir Soofi. "." JMIR Research Protocols 9 , no. 8 (2020) : p.e19001
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Cash transfer
  • Behavior change communication (BCC)
Research Gaps
  • Cost
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Jeanette Bailey. "." PLoS Med 17 , no. 7 (2020) : e1003192
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Cost
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Ye Shen, Ilana R. Cliffer, Devika J. Suri, Breanne K. Langlois, Stephen A. Vosti, Patrick Webb, Beatrice L. Rogers. "." Nutrition Journal 19 , no. 1 (2020) : 1-18
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Ilana R Cliffer, Laetitia Nikiema, Breanne K Langlois, Augustin N Zeba, Ye Shen, Hermann B Lanou, Devika J Suri, Franck Garanet, Kenneth Chui, Stephen Vosti, Shelley Walton, Irwin Rosenberg, Patrick Webb, Beatrice L Rogers. "." Current Developments in Nutrition 4 , no. 2 (2020)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Mark Manary, Meghan Callaghan-Gillespie. "." Global Landscape of Nutrition Challenges in Infants and Children 93 (2020) : 111-120
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Cost
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
  • Treatment of Moderate Acute Malnutrition
Shen Y, Griswold S, Langlois B, Suri D, Vosti S, Webb P, Rogers B.. "." Current Developments in Nutrition 3 , no. Supp 1 (2019) : P10-142-19
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Cost
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Isanaka S, Barnhart DA, McDonald CM, Ackatia-Armah RS, Kupka R, Doumbia S, Brown KH, Menzies NA. "." BMJ Global Health 4 , no. 2 (2019)
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Cost
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Pernilla Svefors , Katarina Ekholm Selling, Rubina Shaheen, Ashraful Islam Khan, Lars-Åke Persson, Lars Lindholm. "." PLoS ONE 13 , no. 2 (2018)
Study Interventions
  • Other
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Eleanor Rogers, Karen Martínez, Jose Luis Alvarez Morán, Franck G. B. Alé, Pilar Charle, Saul Guerrero, Chloe Puett. "." Human Resources for Health 16 , no. 1 (2018)
Study Interventions
  • Other
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Humber, J., Vosti, S. A., Cummins, J., Mridha, M., Matias, S. L., Dewey, K.. "The Rang-Din Nutrition Study in rural Bangladesh: the costs and cost-effectiveness of programmatic interventions to improve linear growth at birth and 18 months, and the costs of these interventions at 24 months ." FANTA III Food and Nutrition Technical Assistance Report (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Lagrone, L., Cole, S., Schondelmeyer, A., Maleta, K., Manary, M. J.. "." Annals of Tropical Paediatrics 30 , no. 2 (2010)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Cost
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Weber, J. M., Ryan, K. N., Tandon, R., Mathur, M., Girma, T., Steiner-Asiedu, M., Saalia, F., Zaidi, S., Soofi, S., Okos, M., Vosti, S. A.. "Acceptability of locally produced ready-to-use therapeutic foods in Ethiopia, Ghana, Pakistan and India ." Maternal & Child Nutrition 13 , no. 2 (2017) : e12250
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Cost
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Isanka, S., Menzies, N. A., Sayyad, J., Ayoola, M., Grais, R. F., Doyon, S.. "Cost analysis of the treatment of severe acute malnutrition in West Africa ." Maternal & Child Nutrition (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Animal-source protein
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Rogers, B. L., Wilner, L., Maganga, G., Walton, S., Suri, D. J., Langlois, B., Chui, K. K. H., Boiteau, J., Vosti, S., Webb, P.. "Program changes are effective and cost-effective in increasing the amount of oil used in preparing corn soy blend porridge for treatment of moderate acute malnutrition in Malawi ." Maternal & Child Nutrition (2017)
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Cost
  • Efficacy
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Irena, A., Bahwere, P., Owino, V., Diop, E. I., Bachmann, M., Mbwili-Muleya, C., Dibari, F., Sadler, K., Collins, S.. "      ." Maternal & Child Nutrition 11 , no. S4 (2015) : 105-119
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Composition
  • Cost
  • Efficacy
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Koroma, A., Manary, M., Marron, B., Green, J., Rogers, B., Walton, S., Chui, K. H. K., Suri, D., Langlois, B., Jayson, L., Boiteau, J., Rosenberg, I., de Pee, S., Vosti, S., Webb, P.. "Comparison of four supplementary foods in treating moderate acute malnutrition in Sierra Leone: an Ebola-constrained cluster-randomized, controlled clinic-based effectiveness trial: A Report from the Food Aid Quality Review ." (2015)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Cost
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Bechman, A., Phillips, R. D., Chen, J.. "The use of nutrient-optimizing/cost-minimizing software to develop ready-to-use therapeutic foods for malnourished pregnant women in Mali ." Food Science & Nutrition 3 , no. 2 (2015) : 110-119
Study Interventions
  • Plant-source protein
  • Locally produced
Research Gaps
  • Cost
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Fenn, B., Sangrasi, G. M., Puett, C., Trenouth, L., Pietzsch, S.. "The REFANI Pakistan study-a cluster randomised controlled trial of the effectiveness and cost-effectiveness of cash-based transfer programmes on child nutrition status: study protocol ." BMC Public Health 15 , no. 1 (2015) : 1044
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Cash transfer
  • Behavior change communication (BCC)
  • Micronutrient powders (MNP)
Research Gaps
  • Cost
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Tonguet-Papucci, A., Huybregts, L., Aissa, M. A.. "The MAM'Out project: a randomized controlled trial to assess multiannual and seasonal cash transfers for the prevention of acute malnutrition in children ." BMC Public Health (2015)
Study Interventions
  • Cash transfer
Research Gaps
  • Cost
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Puett, C., Sadler, K., Alderman, H., Coates, J., Fiedler, J. L., Myatt, M.. "Cost-effectiveness of the community-based management of severe acute malnutrition by community health workers in southern Bangladesh ." Health Policy and Planning 28 , no. 4 (2013) : 386-399
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition