Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 65 Results
Marius Affonfere, Flora Josiane Chadare, Finagnon Toyi Kévin Fassinou, Elise F. Talsma, Anita R. Linnemann, Paulin Azokpota. "." Food Science & Nutrition (2021)
Study Interventions
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Acceptability
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Stark, Heather, Anteneh Omer, Aïssata Wereme N'Diaye, Amanda C. Sapp, Emily V. Moore, Sarah L. McKune. "." Maternal & Child Nutrition (2020) : e13069
Study Interventions
  • Behavior change communication (BCC)
  • Locally produced
  • Animal-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Gul Nawaz Khan, Sumra Kureishy, Shabina Ariff, Arjumand Rizvi, Muhammad Sajid, Cecilia Garzon, Ali Ahmad Khan, Saskia de Pee, Sajid Bashir Soofi, Zulfiqar A. Bhutta. "." PloS one 15 , no. 8 (2020) : p.e0237210
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Azimi F, Esmaillzadeh A, Alipoor E, Moslemi M, Yaseri M, Hosseinzadeh-Attar MJ. "." Public Health , no. 185 (2020) : 290-297
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Composition
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Susan B Roberts, Maria A Franceschini, Rachel E Silver, Salima F Taylor, Augusto Braima de Sa, Raimundo Có, Aliu Sonco, Amy Krauss, Patrick Webb , Amy Taetzsch, Sai Krupa Das, C-Y Chen, Beatrice L Rogers, Edward Saltzman, Pei-Yi Lin, Nina Schlossman, William Pruzensky, Carlito Balé, Kenneth Kwan Ho Chui, Paul Muentener. "." BMJ (2020) : 370
Study Interventions
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Bindi Borg , Daream Sok, Seema Mihrshahi, Mark Griffin, Chhoun Chamnan, Jacques Berger, Arnaud Laillou, Nanna Roos, and Frank T. Wieringa. "." Maternal and Child Nutrition 16 , no. 1 (2020)
Study Interventions
  • Standard Fortified Food Blends
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Sika M Kumordzie, Seth Adu-Afarwuah, Mary Arimond, Rebecca R Young, Theodosia Adom, Rose Boatin, Maku E Ocansey, Harriet Okronipa, Elizabeth L Prado, Brietta M Oaks, and Kathryn G Dewey.. "." The Journal of Nutrition 149 , no. 5 (2019) : 847–855
Study Interventions
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Briony Stevens, Kerrianne Watt, Julie Brimbecombe, Alan Clough, Jenni A. Judd, and Daniel Lindsay. "   ." BMC Pregnancy & Childbirth 18 (2018) : 286
Study Interventions
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Bindi Borg, Seema Mihrshahi, Mark Griffin, Daream Sok, Chamnan Chhoun, Arnaud Laillou, Frank T. Wieringa. "." Maternal & Child Nutrition 15 , no. 3 (2019)
Study Interventions
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Acceptability
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Nawaz G, Ariff S, Habib A, Kureishy S, Garzon C, Ihtesham Y, Khan AA, Sajid M, Ahmed I, Soofi S. "." Current Developments in Nutrition 3 (2019)
Study Interventions
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Kwaku Tano-Debrah, Firibu Kwesi Saalia, Shibani Ghosh, Masashi Hara. "." Food And Nutrition Bulletin (2019)
Study Interventions
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Jadhav AR, Karnik P, Fernandes L, Fernandes S, Shah N, Manglani M.. "." Indian Pediatrics 56 , no. 4 (2019) : 287-293
Study Interventions
  • Locally produced
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Susan B. Roberts, Maria Angela Franceschini, Amy Krauss, Pei-Yi Lin, Augusto Braima de Sa, Raimundo Co ́, SalimaTaylor, Carrie Brown, Oliver Chen, Elizabeth J. Johnson, William Pruzensky, Nina Schlossman, Carlito Bale ́, Kuan-Cheng (Tony) Wu, Katherine Hagan, Edward Saltzman, Paul Muentener. "." Current Developments in Nutrition 1 , no. 11 (2017)
Study Interventions
  • Standard Fortified Food Blends
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Avula, R., Frongillo, E. A., Arabi, M., Sharma, S., Schultink, W.. "Enhancements to nutrition program in Indian Integrated Child Development Services increased growth and energy intake of children ." The Journal of Nutrition 141 (2011) : 680-684
Study Interventions
  • Other
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Lagrone, L., Cole, S., Schondelmeyer, A., Maleta, K., Manary, M. J.. "." Annals of Tropical Paediatrics 30 , no. 2 (2010)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Cost
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Dube, B., Rongsen, T., Mazumder, S., Taneja, S., Rafiqui, F., Bhandari, N., Bhan, M. K.. "Comparison of ready-to-use therapeutic food with cereal legume-based Khichri among malnourished children ." Indian Pediatrics 46 (2009) : 383-388
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Acceptability
  • Composition
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Ackatia-Armah, R. S., McDonald, C., Doumbia, S., Brown, K. H.. "Effect of selected dietary regimens on recovery from moderate acute malnutrition in young Malian children ." The FASEB Journal 26 , no. 1 (2012)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Lin, C. A., Manary, M. J., Maleta, K., Briend, A., Ashorn, P.. "An energy-dense complementary food is associated with a modest increase in weight gain when compared with a fortified porridge in Malawian children aged 6–18 months ." Journal of Nutrition 138 (2008) : 593-598
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Stevens, B., Watt, K., Brimblecombe, J., Clough, A., Judd, J.. "Development of a locally produced, balanced protein-energy food-based supplement and its acceptance by undernourished pregnant women in Northern Bangladesh ." Journal of Hunger & Environmental Nutrition (2016) : 100-115
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Delimont, N. M., Alavi, S., Lindshield, B.. "New formulations for fortified-blended foods: the MFFAPP Tanzania efficacy trial ." The FASEB Journal 31 , no. 1 (2017) : Supplement 786.15
Study Interventions
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Sulistiyono, P., Herawati, D. M. D., Arya, I. F. D.. "Rebon shrimp powder addition influence to nutritional values, organoleptic properties and acceptance of supplementary food by children aged 4-5 years old ." Kesmas: National Public Health Journal 11 , no. 4 (2017) : 168-172
Study Interventions
  • Locally produced
  • Animal-source protein
Research Gaps
  • Acceptability
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Mehta, R., Platt, A. C., Sun, X., Desai, M., Clements, D., Turner, E. L.. "Efficacy of iron-supplement bars to reduce anemia in urban Indian women: a cluster-randomized controlled trial ." The American Journal of Clinical Nutrition (2017)
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Martorell, R.. "Improved nutrition in the first 1000 days and adult human capital and health ." American Journal of Human Biology 29 , no. 2 (2017)
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Thapa, B. R., Goyal, P., Menon, J., Sharma, A.. "Acceptability and efficacy of locally produced ready-to-use therapeutic food nutreal in the management of severe acute malnutrition in comparison with defined food: A randomized control trial ." Food and Nutrition Bulletin 38 , no. 1 (2017) : 18-26
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Weber, J. M., Ryan, K. N., Tandon, R., Mathur, M., Girma, T., Steiner-Asiedu, M., Saalia, F., Zaidi, S., Soofi, S., Okos, M., Vosti, S. A.. "Acceptability of locally produced ready-to-use therapeutic foods in Ethiopia, Ghana, Pakistan and India ." Maternal & Child Nutrition 13 , no. 2 (2017) : e12250
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Cost
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition