Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 22 of 22 Results
Boris Martinez, Meghan Farley Webb, Ana Gonzalez, Kate Douglas, Maria del Pilar Grazioso, Peter Rohloff. "." BMJ Paediatrics Open 2 , no. 1 (2018)
Study Interventions
  • Other
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Pernilla Svefors , Katarina Ekholm Selling, Rubina Shaheen, Ashraful Islam Khan, Lars-Åke Persson, Lars Lindholm. "." PLoS ONE 13 , no. 2 (2018)
Study Interventions
  • Other
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Zeweter Abebe , Gulelat Desse Haki, Kaleab Baye. "." Maternal and Child Nutrition 14 , no. 1 (2017)
Study Interventions
  • Standard Fortified Food Blends
  • Other
  • Micronutrient powders (MNP)
Research Gaps
  • Efficacy
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Eleanor Rogers, Karen Martínez, Jose Luis Alvarez Morán, Franck G. B. Alé, Pilar Charle, Saul Guerrero, Chloe Puett. "." Human Resources for Health 16 , no. 1 (2018)
Study Interventions
  • Other
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Avula, R., Frongillo, E. A., Arabi, M., Sharma, S., Schultink, W.. "Enhancements to nutrition program in Indian Integrated Child Development Services increased growth and energy intake of children ." The Journal of Nutrition 141 (2011) : 680-684
Study Interventions
  • Other
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Pulungan, A. B., Mirasanti, D. A.. "Effect of community-based food supplementation on improving growth of underweight children under five years of age in West Nusa Tenggara ." Paediatrica Indonesiana 57 , no. 5 (2017) : 246-251
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Rytter, M. J., Babirekere-Iriso, E., Namusoke, H., Christensen, V. B., Michaelsen, K. F., Ritz, C., Mortensen, C. G., Mupere, E., Friis, H.. "Risk factors for death in children during inpatient treatment of severe acute malnutrition: a prospective cohort study ." The American Journal of Clinical Nutrition 105 , no. 2 (2017) : 494-502
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Magnin, M., Stoll, B., Voahangy, R., Jeannot, E.. "Most children who took part in a comprehensive malnutrition programme in Madagascar reached and maintained the recovery threshold ." Acta Paediatrica 106 , no. 6 (2017) : 960-966
Study Interventions
  • Standard Fortified Food Blends
  • Other
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Bhandari, N., Mohan, S. B., Bose, A., Iyengar, S. D., Taneja, S., Mazumder, S., Pricilla, R. A., Iyengar, K., Sachdev, H. S., Mohan, V. R., Suhalka, V., Yoshida, S., Martines, J., Bahl, R.. "Efficacy of three feeding regimens for home-based management of children with uncomplicated severe acute malnutrition: a randomised trial in India ." BMJ Global Health 1 , no. e000144 (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Other
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Jayson, L., Passarelli, S., Suri, D., Maganga, G., Marcus, S., Webb, P., Rogers, B.. "The price of oil: Behavior change communication and increased oil ration improve mothers' uses of vegetable oil in preparing food aid rations for children in Malawi ." The FASEB Journal 29 , no. 1 Supplement 898.21 (2015)
Study Interventions
  • Behavior change communication (BCC)
  • Standard Fortified Food Blends
  • Other
Research Gaps
  • Innovation
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Pandya, V. P., Joshi, I. V., Sheth, A. M., Kadri, A. M.. "Studying the effectiveness of mixed models of community based and institutional based interventions for management of severe acute malnourished children ." International Journal of Research in Medical Sciences 3 , no. 7 (2015) : 1758-1764
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Other
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Isanaka, S., Langendorf, C., Berthé, F., Gnegne, S., Li, N., Ousmane, N., Harouna, S., Hassane, H., Schaefer, M., Adehossi, E., Grais, R. F.. "Routine amoxicillin for uncomplicated severe acute malnutrition in children ." The New England Journal of Medicine 374 (2016) : 444-453
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Other
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Kerac, M., Bunn, J., Seal, A., Thindwa, M., Tomkins, A., Sadler, K., Bahwere, P., Collins, S.. "Probiotics and prebiotics for severe acute malnutrition (PRONUT study): a double-blind efficacy randomised controlled trial in Malawi ." The Lancet 374 , no. 9684 (2009) : 136-144
Study Interventions
  • Other
  • Animal-source protein
Research Gaps
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Simpore, J., Kabore, F., Zongo, F., Dansou, D., Bere, A., Pignatelli, S., Biondi, D. M., Ruberto, G., Musumeci, S.. "Nutrition rehabilitation of undernourished children utilizing Spiruline and Misola ." Nutrition Journal 5 , no. 3 (2006)
Study Interventions
  • Other
  • Locally produced
Research Gaps
  • Composition
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Scherbaum, V., Purwestri, R. C., Stuetz, W., Inayati, D. A., Suryantan, J., Bloem, M. A., Biesalski, H. K.. "Locally produced cereal/nut/legume-based biscuits versus peanut/milk-based spread for treatment of moderately to mildly wasted children in daily programmes on Nias Island, Indonesia: an issue of acceptance and compliance? ." Asia Pacific Journal of Clinical Nutrition 24 , no. 1 (2015) : 152
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Other
  • Behavior change communication (BCC)
  • Animal-source protein
Research Gaps
  • Acceptability
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Ningadalli, S. G., Angolkar, M., Herekar, V. R., Hirachand, A. D., Sah, J. K., Madikar, S.. "." International Journal of Science and Research 4 , no. 5 (2015) : 2133-2137
Study Interventions
  • Other
  • Behavior change communication (BCC)
Research Gaps
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Kerac, M., Bunn, J., Chagaluka, G., Bahwere, P., Tomkins, A., Collins, S., Seal, A.. "Follow-up of post-discharge growth and mortality after treatment for severe acute malnutrition (FuSAM study): a prospective cohort study ." PloS One 9 , no. 6 (2014) : e96030
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Lebenthal, Y., Yackobovitch-Gavan, M., Lazar, L., Shalitin, S., Tenenbaum, A., Shamir, R., Phillip, M.. "Effect of a nutritional supplement on growth in short and lean prepubertal children: a prospective, randomized, double-blind, placebo-controlled study ." The Journal of Pediatrics 165 , no. 6 (2014) : 1190-1193.e1
Study Interventions
  • Other
  • Animal-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Khan, A. I. , Kabir, I., Hawkesworth, S., Ekström, E., Arifeen, S., Frongillo, E. A., Persson, L. A.. "Early invitation to food and/or multiple micronutrient supplementation in pregnancy does not affect body composition in offspring at 54 months: follow-up of the MINIMat randomised trial, Bangladesh ." Maternal & Child Nutrition 11 , no. 3 (2013) : 385-397
Study Interventions
  • Other
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Diop, E. H. I., Dossou, N. I., Ndour, M. M., Briend, A., Wade, S.. "Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: A randomized trial ." American Journal of Clinical Nutrition 78 , no. 2 (2003) : 302-307
Study Interventions
  • Animal-source protein
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Langendorf, C., Roederer, T., de Pee, S., Brown, D., Doyon, S., Mamaty, A., Touré, L. W., Manzo, M. L., Grais, R. F.. "Preventing acute malnutrition among young children in crises: A prospective intervention study in Niger ." PLOS Medicine (2012)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Other
  • Cash transfer
  • Animal-source protein
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Portillo-Reyes, V., Pérez-García, M., Loya-Méndez, Y., Puente, A. E.. "Clinical significance of neuropsychological improvement after supplementation with omega-3 in 8–12 years old malnourished Mexican children: A randomized, double-blind, placebo and treatment clinical trial ." Research in Developmental Disabilities 35 , no. 4 (2014) : 861-870
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition