Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 17 of 17 Results
Ackatia-Armah, R. S., McDonald, C., Doumbia, S., Brown, K. H.. "Effect of selected dietary regimens on recovery from moderate acute malnutrition in young Malian children ." The FASEB Journal 26 , no. 1 (2012)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Abizari, A., Moretti, D., Zimmermann, M. B., Armar-Klemesu, M., Brouwer, I. D.. "Whole cowpea meal fortified with NaFeEDTA reduces iron deficiency among Ghanaian school children in a malaria endemic area ." The Journal of Nutrition 142 , no. 10 (2012) : 1836-1842
Study Interventions
  • Standard Fortified Food Blends
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Karakochuk, C., van den Briel, T., Stephens, D., Zlotkin, S.. "Treatment of moderate acute malnutrition with ready-to-use supplementary food results in higher overall recovery rates compared with a corn-soya blend in children in southern Ethiopia: an operations research trial ." The American Journal of Clinical Nutrition 96 , no. 4 (2012) : 911-6
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Huybregts, L., Houngbé, F., Salpéteur, C., Brown, R., Roberfroid, D., Ait-Aissa, M., Kolsteren, P.. "The effect of adding ready-to-use supplementary food to a general food distribution on child nutritional status and morbidity: a cluster-randomized controlled trial ." PLoS Medicine 9 , no. 9 (2012) : e1001313
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Purwestri, R. C., Scherbaum, V., Inayati, D. A., Wirawan, N. N., Suryantan, J., Bloem, M. A., Pangaribuan, R. V., Stuetz, W., Hoffmann, V., Qaim, M., Biesalski, H. K., Bellows, A. C.. "Supplementary feeding with locally-produced ready-to-use food (RUF) for mildly wasted children on Nias island, Indonesia: Comparison of daily and weekly program outcomes ." Asia Pacific Journal of Clinical Nutrition 21 , no. 3 (2012) : 374
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Bisimwa, G., Owino, V. O., Bahwere, P., Dramaix, M., Donnen, P., Dibari, F., Collins, S.. "Randomized controlled trial of the effectiveness of a soybean-maize-sorghum-based ready-to-use complementary food paste on infant growth in South Kivu, Democratic Republic of Congo ." American Journal of Clinical Nutrition 95 , no. 5 (2012) : 1157-1164
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Dewey, K. G., Arimond, M.. "Lipid-based nutrient supplements: how can they combat child malnutrition? ." PLoS Medicine 9 , no. 9 (2012) : e1001314
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
  • Treatment of Severe Acute Malnutrition
Cohuet, S., Marquer, C., Shepherd, S., Captier, V., Langendorf, C., Ale, F., Phelan, K., Manzo, M. L., Grais, R. F.. "Intra-household use and acceptability of Ready-to-Use-Supplementary-Foods distributed in Niger between July and December 2010 ." Appetite 59 , no. 3 (2012) : 698-705
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Pongcharoen, T., Ramakrishnan, U., DiGirolamo, A.M., Winichagoon, P., Flores, R., Singkhornard, J., Martorell, R.. "Influence of prenatal and postnatal growth on intellectual functioning in school-aged children ." Archives of Pediatrics & Adolescent Medicine 166 , no. 5 (2012) : 411-416
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Mridha, M. K., Chaparro, C. M., Matias, S., Hussain, S., Munira, S.. "Acceptability of lipid-based nutrient supplements and micronutrient powders among pregnant and lactating women and infants and young children in Bangladesh and their perceptions about malnutrition and nutrient supplements ." FANTA 2 Technical Report (2012)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Grellety, E., Shepherd, S., Roederer, T., Manzo, M. L., Doyon, S., Ategbo, E., Grais, R. F.. "Effect of mass supplementation with ready-to-use supplementary food during an anticipated nutritional emergency ." PloS One 7 , no. 9 (2012) : e44549
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Phuka, J. C., Gladstone, M., Maleta, K., Thakwalakwa, C., Cheung, Y. B., Briend, A., Manary, M. J., Ashorn, P.. "Developmental outcomes among 18‐month‐old Malawians after a year of complementary feeding with lipid‐based nutrient supplements or corn‐soy flour ." Maternal & Child Nutrition 8 , no. 2 (2012) : 239-248
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Langendorf, C., Roederer, T., de Pee, S., Brown, D., Doyon, S., Mamaty, A., Touré, L. W., Manzo, M. L., Grais, R. F.. "Preventing acute malnutrition among young children in crises: A prospective intervention study in Niger ." PLOS Medicine (2012)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Other
  • Cash transfer
  • Animal-source protein
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Manary, M., Chang, C.. "." FANTA Project (2012)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Locally produced
  • Animal-source protein
Research Gaps
  • Composition
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Thakwalakwa, C. M., Ashorn, P., Jawati, M., Phuka, J. C., Cheung, Y. B., Maleta, K. M.. "An effectiveness trial showed lipid-based nutrient supplementation but not corn-soya blend offered a modest benefit in weight gain among 6- to 18-month-old underweight children in rural Malawi ." Public Health Nutrition 15 , no. 9 (2012) : 1755-62
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Locally produced
  • Animal-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Mangani, C., Manary, M., Alho, L., Ashorn, P.. "A single-centre, randomized, single-blind, parallel group clinical trial in rural Malawi, testing the growth promoting effect of long-term complementary feeding of infants with a high-energy, micronutrient fortified spread ." FANTA Project (2012)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
LaGrone, L. N., Trehan, I., Meuli, G. J., Wang, R. J., Thakwalakwa, C., Maleta, K., Manary, M. J.. "A novel fortified blended flour, corn-soy blend "plus-plus," is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children ." The American Journal of Clinical Nutrition 95 , no. 1 (2012) : 212-9
Study Interventions
  • Animal-source protein
  • Standard Fortified Food Blends
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition