Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 16 of 16 Results
Hirve, S., Martini, E., Juvekar, S. K., Agarwal, D., Bavdekar, A., Sari, M., Molwane, M., Janes, S., Haselow, N., Yeung, D. L., Pandit, A.. "." The Indian Journal of Pediatrics 80 , no. 12 (2013) : 990-995
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Jie, C.. "Improve nutrition, food safety, and food security for China’s most vulnerable women and children – Joint final evaluation ." International Labor Office - Evaluation Unit (2013)
Study Interventions
  • Micronutrient powders (MNP)
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Segrè, J., Winnard, K., Abrha, T. H., Abebe, Y., Shilane, D., Lapping, K.. "Willingness to pay for lipid‐based nutrient supplements for young children in four urban sites of Ethiopia ." Maternal & Child Nutrition 11 , no. Suppl 4 (2013) : 16-30
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
Flax, V. L., Mäkinen, S., Ashorn, U., Cheung, Y. B., Maleta, K., Ashorn, P., Bentley, M. E.. "Responsive feeding and child interest in food vary when rural Malawian children are fed lipid‐based nutrient supplements or local complementary food ." Maternal & Child Nutrition 9 , no. 3 (2013) : 369-380
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Ali, E., Zachariah, R., Dahmane, A., Van den Boogaard, W., Shams, Z., Akter, T., Alders, P., Manzi, M., Allaouna, M., Draguez, B., Delchevalerie, P., Harries, A. D.. "Peanut-based ready-to-use therapeutic food: acceptability among malnourished children and community workers in Bangladesh ." Public Health Action 3 , no. 2 (2013) : 128-135
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Flax, V. L., Bentley, M. E., Chasela, C. S., Kayira, D., Hudgens, M. G., Kacheche, K. Z., Chavula, C., Kourtis, A. P., Jamieson, D. J., van der Horst, C. M.. "Lipid-based nutrient supplements are feasible as a breastmilk replacement for HIV-exposed infants from 24 to 48 weeks of age ." The Journal of Nutrition 143 , no. 5 (2013) : 701-707
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Cercamondi, C. I., Egli, I. M., Mitchikpe, E., Tossou, F., Hessou, J., Zeder, C., Hounhouigan, J. D., Hurrell, R. F.. "Iron bioavailability from a lipid-based complementary food fortificant mixed with millet porridge can be optimized by adding phytase and ascorbic acid but not by using a mixture of ferrous sulfate and sodium iron EDTA ." The Journal of Nutrition 143 , no. 8 (2013) : 1233-1239
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Composition
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Wang, R. J., Trehan, I., LaGrone, L. N., Weisz, A. J., Thakwalakwa, C. M., Maleta, K. M., Manary, M. J.. "Investigation of food acceptability and feeding practices for lipid nutrient supplements and blended flours used to treat moderate malnutrition ." Journal of Nutrition Education and Behavior 45 , no. 3 (2013) : 258-263
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Purwestri, R. C., Scherbaum, V., Inayati, D. A., Wirawan, N. N., Suryantan, J., Bloem, M. A., Pangaribuan, R. V., Stuetz, W., Hoffmann, V., Qaim, M., Biesalski, H. K., Bellows, A. C.. "Impact of daily versus weekly supply of locally produced ready-to-use food on growth of moderately wasted children on Nias Island, Indonesia ." ISRN Nutrition 2013 (2013) : 412145
Study Interventions
  • Plant-source protein
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Smith, M. I., Yatsunenko, T., Manary, M. J., Trehan, I., Mkakosya, R., Cheng, J., Kau, A. L., Rich, S. S., Concannon, P., Mychaleckyj, J. C., Liu, J., Houpt, E., Li, J. V., Holmes, E., Nicholson, J., Knights, D., Ursell, L. K., Knight, R., Gordon, J. I.. "Gut microbiomes of Malawian twin pairs discordant for kwashiorkor ." Science 339 , no. 6119 (2013) : 548-554
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Tripp, K., Clayton, H., Nanema, A., Mujinga, W., Kupka, R., Sandalinas, F., Nanama, S., Jungjohann, S., Chatelier, M. L., Palma, C.. "Formative assessment to design the packaging of a lipid-based nutrient supplement for a home fortification program to improve the nutritional status of young children in the Democratic Republic of Congo (DRC) ." (2013)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Prevention of Stunting, Wasting, and Underweight
  • Treatment of Severe Acute Malnutrition
Shewade, H. D., Patro, B. K., Bharti, B., Soundappan, K., Kaur, A., Taneja, N.. "Effectiveness of indigenous ready-to-use therapeutic food in community-based management of uncomplicated severe acute malnutrition: a randomized controlled trial from India ." Journal of Tropical Pediatrics 59 , no. 5 (2013) : 393-8
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Khan, A. I. , Kabir, I., Hawkesworth, S., Ekström, E., Arifeen, S., Frongillo, E. A., Persson, L. A.. "Early invitation to food and/or multiple micronutrient supplementation in pregnancy does not affect body composition in offspring at 54 months: follow-up of the MINIMat randomised trial, Bangladesh ." Maternal & Child Nutrition 11 , no. 3 (2013) : 385-397
Study Interventions
  • Other
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Puett, C., Sadler, K., Alderman, H., Coates, J., Fiedler, J. L., Myatt, M.. "Cost-effectiveness of the community-based management of severe acute malnutrition by community health workers in southern Bangladesh ." Health Policy and Planning 28 , no. 4 (2013) : 386-399
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Chang, C. Y., Trehan, I., Wang, R. J., Thakwalakwa, C., Maleta, K., Deitchler, M., Manary, M. J.. "Children successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery ." The Journal of Nutrition 143 , no. 2 (2013) : 215-220
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
  • Plant-source protein
  • Animal-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Trehan, I., Goldbach, H. S., LaGrone, L. N., Meuli, G. J., Wang, R. J., Maleta, K. M., Manary, M. J.. "Antibiotics as part of the management of severe acute malnutrition ." New England Journal of Medicine 368 , no. 5 (2013) : 425-435
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition