Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 43 Results
Marly A. Cardoso , Rosangela A. Augusto, Gisele A. Bortolini, Cristieli S. M. Oliveira, Daniela C. Tietzman, Leopoldina A. S. Sequeira, Maria Claret C. M. Hadler, Maria do Rosario G. Peixoto, Pascoal T. Muniz, Márcia R. Vitolo, Pedro I. C. Lira, Patrícia C. Jaime, ENFAC Working Group. "." PLOS ONE 11 , no. 5 (2016)
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Christian Fabiansen, Kevin PQ Phelan, Bernardette Cichon, Christian Ritz, André Briend, Kim F Michaelsen, Henrik Friis, Susan Shepherd. "." American Journal of Clinical Nutrition 103 , no. 2 (2016) : 415-421
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Harding, K. L., Matias, S. L., Moniruzzaman, M., Mridha, M. K., Vosti, S. A., Dewey, K. G.. "Rang-Din Nutrition Study: assessment of adherence to lipid-based nutrient supplements and micronutrient powders among children 6-23 months in Bangladesh ." FANTA III Food and Nutrition Technical Assistance Report (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Dewey, K. G., Mridha, M. K., Matias, S. L., Cummins, J. R., Peerson, J. M., Arnold, C. D., Young, R. T., Vosti, S. A.. "Effectiveness of a lipid-based nutrient supplement (LNS) intervention on pregnancy and birth outcomes in Bangladesh ." FANTA III: Food and Nutrition Technical Assistance Report (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Stevens, B., Watt, K., Brimblecombe, J., Clough, A., Judd, J.. "Development of a locally produced, balanced protein-energy food-based supplement and its acceptance by undernourished pregnant women in Northern Bangladesh ." Journal of Hunger & Environmental Nutrition (2016) : 100-115
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Suchdev, P. S., Addo, O. Y., Martorell, R., Grant, F. K. E., Ruth, L. J., Patel, M. K., Juliao, P. C., Quick, R., Flores-Ayala, R.. "Effects of community-based sales of micronutrient powders on morbidity episodes in preschool children in Western Kenya ." American Journal of Clinical Nutrition 103 , no. 3 (2016) : 934-941
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Iannotti, L., Dulience, S. J., Joseph, S., Cooley, C., Tufte, T., Cox, K., Eaton, J., Delnatus, J. R., Wolff, P. B.. "Fortified snack reduced anemia in rural school-aged children of Haiti: a cluster-randomized, controlled trial ." Plos One 11 , no. 12 (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Jadhav, A., Dias, B., Shah, N., Fernandes, L., Fernandes, S., Surve, A., Dhami-Shah, H., Murty, S., Joshi, N., Manglani, M.. "A randomized controlled facility based trial to assess the impact of indigenously prepared ready to use therapeutic food (RUTF) for children with severe acute malnutrition in India ." Pediatric Oncall Journal 13 , no. 4 (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Bhandari, N., Mohan, S. B., Bose, A., Iyengar, S. D., Taneja, S., Mazumder, S., Pricilla, R. A., Iyengar, K., Sachdev, H. S., Mohan, V. R., Suhalka, V., Yoshida, S., Martines, J., Bahl, R.. "Efficacy of three feeding regimens for home-based management of children with uncomplicated severe acute malnutrition: a randomised trial in India ." BMJ Global Health 1 , no. e000144 (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Other
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Isanka, S., Menzies, N. A., Sayyad, J., Ayoola, M., Grais, R. F., Doyon, S.. "Cost analysis of the treatment of severe acute malnutrition in West Africa ." Maternal & Child Nutrition (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Animal-source protein
Research Gaps
  • Cost
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Zhang, Y., Wu, Q., Wang, W., van Velthoven, M. H., Chang, Z., Han, H., Xing, M., Chen, L., Scherpbier, R. W.. "Effectiveness of complementary food supplements and dietary counselling on anaemia and stunting in children aged 6–23 months in poor areas of Qinghai Province, China: a controlled interventional study ." BMJ Open 6 , no. e011234 (2016)
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Dani, V., Stav, A., Pendharkar, J., Satav, K., Sadanshiv, A., Adhav, A. S., Thakare, B.. "Community-based management of severe malnutrition: SAM and SUW in children under five in the Melghat tribal area, central India ." ENN Field Exchange 52 (2016) : 27
Study Interventions
  • Plant-source protein
  • Behavior change communication (BCC)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Iuel-Brockdorf, A., Ouedraogo, A., Ritz, C., Draebel, T. A., Ashorn, P., Filteau, S., Michaelsen, K. F.. "Feeding behaviors during home-based treatment of moderate acute malnutrition using corn-soy blends or lipid-based nutrient supplements ." Maternal & Child Nutrition (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Nisbett, N., Longhurst, R., Barnett, I., Feruglio, F., Gordon, J., Hoddinott, J., Jahan, F., Karachiwalla, N., Roy, S., Shah, V., Siddiki, O. F., Tranchant, J. P., White, J.. "Impact evaluation of the DFID Programme to accelerate improved nutrition for the extreme poor in Bangladesh: Final Report ." DFID (2016)
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Moramarco, S., Amerio, G., Ciarlantini, C., Chipoma, J. K., Simpungwe, M. K., Nielsen-Saines, K., Palombi, L., Buonomo, E.. "Community-based management of child malnutrition in Zambia: HIV/AIDS infection and other risk factors on child survival ." International Journal of Environmental Research and Public Health 13 , no. 7 (2016) : 666
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition
Kumwenda, G., Nhlema, B., Maganga, G., Rogers, B., Walton, S., Boiteau, J., Webb, P.. "Feasibility and acceptability study of preparing corn soy blend with fortified vegetable oil in Malawi: Formative research ." USAID Food Aid Quality Review (2016)
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Bailey, J., Chase, R., Kerac, M., Briend, A., Manary, M., Opondo, C., Gallagher, M., Kim, A.. "Combined protocol for SAM/MAM treatment: The ComPAS study ." ENN Online Field Exchange No. 53 (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition
Yousafzai, A. K., Obradović, J., Rashee, M. A., Rizvi, A., Portilla, X. A., Tirado-Strayer, N., Siyal, S., Memon, U.. "Effects of responsive stimulation and nutrition interventions on children's development and growth at age 4 years in a disadvantaged population in Pakistan: A longitudinal follow-up of a cluster-randomised factorial effectiveness trial       ." The Lancet Global Health 4 , no. 8 (2016) : e548-e558
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Leyvraz, M., Rohner, F., Konan, A. G., Esso, L. J. C. E., Woodruff, B. A., Norte, A., Adiko, A. F., Bonfoh, B., Aaron, G. J.. "High awareness but low coverage of a locally produced fortified complementary food in Abidjan, Côte d’Ivoire: Findings from a cross-sectional survey ." PLoS ONE 11 , no. 11 (2016) : e0166295
Study Interventions
  • Locally produced
Research Gaps
  • Innovation
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Leroy, J. L., Olney, D. K., Ruel, M. T.. "Tubaramure, a food-assisted integrated health and nutrition program in Burundi, increases maternal and child hemoglobin concentrations and reduces anemia: A theory-based cluster-randomized controlled intervention trial  ." Journal of Nutrition 146 , no. 8 (2016) : 1601-1608
Study Interventions
  • Standard Fortified Food Blends
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Klevor, M. K., Adu-Afarwuah, S., Ashorn, P., Arimond, M., Dewey, K. G., Lartey, A., Maleta, K., Phiri, N., Pyykko, J., Zeilani, M., Ashorn, U.. "A mixed method study exploring adherence to and acceptability of small quantity lipid-based nutrient supplements (SQ-LNS) among pregnant and lactating women in Ghana and Malawi ." BMC Pregnancy and Childbirth 16 , no. 1 (2016) : 253
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Choudhury, N., Bromage, S., Alam, M. A., Shamsir Ahmed, A. M., Munirul Islam, M., Iqbal Hossain, M., Mahfuz, M., Mondal, D., Ahmed, T.. "Intervention study shows suboptimal growth among children receiving a food supplement for five months in a slum in Bangladesh ." Acta Paediatrica 105 , no. 10 (2016) : e464-e473
Study Interventions
  • Standard Fortified Food Blends
  • Micronutrient powders (MNP)
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Cames, C., Varloteaux, M., Have, N. N., Diom, A. B.,, Msellati, P., Mbaye, N., Mbodji, H., Sy Signate, H., Diack, A., ANRS 12279 MAGGSEN Cohort Study. "Acceptability of outpatient ready-to-use food-based protocols in HIV-infected Senegalese children and adolescents within the MAGGSEN cohort study   ." Food and Nutrition Bulletin 38 , no. 1 (2016) : 27-36
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
  • Treatment of Severe Acute Malnutrition
Adu-Afarwuah, S., Lartey, A., Okronipa, H., Ashorn, P., Peerson, J. M., Arimond, M., Ashorn, U., Zeilani, M., Vosti, S., Dewey, K. G.. "Small-quantity, lipid-based nutrient supplements provided to women during pregnancy and 6 mo postpartum and to their infants from 6 mo of age increase the mean attained length of 18-mo-old children in semi-urban Ghana: a randomized controlled trial ." The American Journal of Clinical Nutrition 104 , no. 3 (2016) : 797-808
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Burza, S., Mahajan, R., Marino, E., Sunyoto, T., Shandilya, C., Tabrez, M., Kumar, K., Jha, A, Mathew, P., Salse, N., Casademont, C., Mishra, N. K.. "Seasonal effect and long-term nutritional status following exit from a Community-Based Management of Severe Acute Malnutrition program in Bihar, India ." European Journal of Clinical Nutrition 70 , no. 4 (2016) : 437-44
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Animal-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition