Published Clinical Trials

This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 126 - 150 of 328 Results
Sulistiyono, P., Herawati, D. M. D., Arya, I. F. D.. "Rebon shrimp powder addition influence to nutritional values, organoleptic properties and acceptance of supplementary food by children aged 4-5 years old ." Kesmas: National Public Health Journal 11 , no. 4 (2017) : 168-172
Study Interventions
  • Locally produced
  • Animal-source protein
Research Gaps
  • Acceptability
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Suchdev, P. S., Addo, O. Y., Martorell, R., Grant, F. K. E., Ruth, L. J., Patel, M. K., Juliao, P. C., Quick, R., Flores-Ayala, R.. "Effects of community-based sales of micronutrient powders on morbidity episodes in preschool children in Western Kenya ." American Journal of Clinical Nutrition 103 , no. 3 (2016) : 934-941
Study Interventions
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Isanka, S., Kodish, S. R., Berthe, F., Alley, I., Nackers, F., Hanson, K. E., Grais, R. F.. "Outpatient treatment of severe acute malnutrition: response to treatment with a reduced schedule of therapeutic food distribution ." The American Journal of Clinical Nutrition (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Iannotti, L., Dulience, S. J., Joseph, S., Cooley, C., Tufte, T., Cox, K., Eaton, J., Delnatus, J. R., Wolff, P. B.. "Fortified snack reduced anemia in rural school-aged children of Haiti: a cluster-randomized, controlled trial ." Plos One 11 , no. 12 (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Manary, M., Callaghan, M., Wegner, D., Papathakis, P.. "Randomized controlled trial of the impact of treating moderately malnourished women in pregnancy ." (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Standard Fortified Food Blends
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Mehta, R., Platt, A. C., Sun, X., Desai, M., Clements, D., Turner, E. L.. "Efficacy of iron-supplement bars to reduce anemia in urban Indian women: a cluster-randomized controlled trial ." The American Journal of Clinical Nutrition (2017)
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Daly, Z., Northrup-Lyons, M., Reid, R., Cheung, M., Hutchinson, D.. "Effectiveness study for the development of a home fortification programme for young children in Zambia - endline report ." (2017)
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Ashorn, P., Poelman, B., Dewey, K. G., Maleta, K., Klein, N., Rogerson, S., Meshnick, S. R., The LNS-RTI Study Team. "The impact of dietary supplementation with lipid-based nutrient supplements on maternal health and pregnancy outcomes in rural Malawi ." (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Rytter, M. J., Babirekere-Iriso, E., Namusoke, H., Christensen, V. B., Michaelsen, K. F., Ritz, C., Mortensen, C. G., Mupere, E., Friis, H.. "Risk factors for death in children during inpatient treatment of severe acute malnutrition: a prospective cohort study ." The American Journal of Clinical Nutrition 105 , no. 2 (2017) : 494-502
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Martorell, R.. "Improved nutrition in the first 1000 days and adult human capital and health ." American Journal of Human Biology 29 , no. 2 (2017)
Study Interventions
  • Locally produced
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Thapa, B. R., Goyal, P., Menon, J., Sharma, A.. "Acceptability and efficacy of locally produced ready-to-use therapeutic food nutreal in the management of severe acute malnutrition in comparison with defined food: A randomized control trial ." Food and Nutrition Bulletin 38 , no. 1 (2017) : 18-26
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Grellety, E., Babakazo, P., Bangana, A., Mwamba, G., Lezama, I., Zagre, N. M., Ategbo, E-A.. " Effects of unconditional cash transfers on the outcome of treatment for severe acute malnutrition (SAM): a cluster-randomised trial in the Democratic Republic of the Congo   ." BMC Medicine 15 , no. 87 (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Cash transfer
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Locks, L. M., Reerink, I., Tucker Brown, A., Gnegne, S., Ramalanjaona, N., Nanama, S., Duggan, C. P., Garg, A.. "The impact of integrated infant and young child feeding and micronutrient powder intervention on feeding practices and anemia in children aged 6-23 months in Madagascar ." Nutrients 9 , no. 6 (2017)
Study Interventions
  • Behavior change communication (BCC)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Style, S., Tondeur, M., Grijalva-Eternod, C., Pringle, J., Kassim, I., Wilkinson, C., Oman, A., Dolan, C., Spiegel, P., Seal, A.. "Assessment of the effectiveness of a small quantity lipid-based nutrient supplement on reducing anaemia and stunting in refugee populations in the Horn of Africa: Secondary data analysis ." PLoS One 12 , no. 6 (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Kodish, S. R., Aburto, N. J., Hambayi, M. N., Dibari, F., Gittelsohn, J.. "Patterns and determinants of small-quantity LNS utilization in rural Malawi and Mozambique: considerations for interventions with specialized nutritious foods ." Maternal & Child Nutrition 13 , no. 1 (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Use
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Houngbe, F., Tonguet-Papucci, A., Altare, C., Ait-Aissa, M., Huneau, J-F., Huybregts, L., Kolsteren, P.. "Unconditional cash transfers do not prevent children's undernutrition in the Moderate Acute Malnutrition Out (MAM'Out) cluster-randomized controlled trial in rural Burkina Faso ." The American Society for Nutrition (2017)
Study Interventions
  • Cash transfer
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Olney, D. K., Bliznashka, L., Becquey, E., Birba, O., Ruel, M.. "Adding a water, sanitation and hygiene intervention and a lipid-based nutrient supplement to an integrated agriculture and nutrition program improved the nutritional status of young Burkinabé children ." The FASEB Journal 31 , no. 1 (2017) : Supplement 455.1
Study Interventions
  • Water, sanitation, hygiene (WASH)
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Weber, J. M., Ryan, K. N., Tandon, R., Mathur, M., Girma, T., Steiner-Asiedu, M., Saalia, F., Zaidi, S., Soofi, S., Okos, M., Vosti, S. A.. "Acceptability of locally produced ready-to-use therapeutic foods in Ethiopia, Ghana, Pakistan and India ." Maternal & Child Nutrition 13 , no. 2 (2017) : e12250
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Locally produced
Research Gaps
  • Acceptability
  • Cost
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Versloot, C. J., Voskuijl, W., van Vliet, S. J., van den Heuvel, M., Carter, J. C., Phiri, A., Kerac, M., Heikens, G. T., van Rheenen, P. F., Bandsma, R. H. J.. " Effectiveness of three commonly used transition phase diets in the inpatient management of children with severe acute malnutrition: a pilot randomized controlled trial in Malawi ." BMC Pediatrics 17 , no. 112 (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Magnin, M., Stoll, B., Voahangy, R., Jeannot, E.. "Most children who took part in a comprehensive malnutrition programme in Madagascar reached and maintained the recovery threshold ." Acta Paediatrica 106 , no. 6 (2017) : 960-966
Study Interventions
  • Standard Fortified Food Blends
  • Other
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Jadhav, A., Dias, B., Shah, N., Fernandes, L., Fernandes, S., Surve, A., Dhami-Shah, H., Murty, S., Joshi, N., Manglani, M.. "A randomized controlled facility based trial to assess the impact of indigenously prepared ready to use therapeutic food (RUTF) for children with severe acute malnutrition in India ." Pediatric Oncall Journal 13 , no. 4 (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition
Matias, S. L., Chaparro, C. M., Perez-Exposito, A. B., Peerson, J. M., Dewey, K. G.. "Acceptability of a lipid-based nutrient supplement among Guatemalan infants and young children ." (2011)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Acceptability
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Fatima, S., Malkova, D., Wright, C., Gerasimidis, K.. "Impact of therapeutic food compared to oral nutritional supplements on nutritional outcomes in mildly underweight healthy children in a low-medium income society ." Clinical Nutrition (2017)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Treatment of Moderate Acute Malnutrition
Fenn, B.. "A cluster RCT to measure the effectiveness and of cash-based interventions on nutrition status, Sindh Province, Pakistan ." ENN Field Exchange 42 (2017) : 61
Study Interventions
  • Cash transfer
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Prevention of Stunting, Wasting, and Underweight
Bhandari, N., Mohan, S. B., Bose, A., Iyengar, S. D., Taneja, S., Mazumder, S., Pricilla, R. A., Iyengar, K., Sachdev, H. S., Mohan, V. R., Suhalka, V., Yoshida, S., Martines, J., Bahl, R.. "Efficacy of three feeding regimens for home-based management of children with uncomplicated severe acute malnutrition: a randomised trial in India ." BMJ Global Health 1 , no. e000144 (2016)
Study Interventions
  • Standard Lipid-Based Nutrient Supplements (LNS)
  • Plant-source protein
  • Other
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Treatment of Severe Acute Malnutrition