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This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 99 Results
Olney, D. K., Pedehombga, A., Ruel, M. T., Dillon, A.. "A 2-year integrated agriculture and nutrition and health behavior change communication program targeted to women in Burkina Faso reduces anemia, wasting, and diarrhea in children 3-12.9 months of age at baseline: a cluster-randomized controlled trial ." The Journal of Nutrition 145 , no. 6 (2015) : 1317-1324
Study Interventions
  • Behavior change communication (BCC)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • MAM
Thakwalakwa, C., Ashorn, P., Phuka, J., Cheung, Y. B., Briend, A., Puumalainen, T., Maleta, K.. "A lipid-based nutrient supplement but not corn-soy blend modestly increases weight gain among 6-to 18-month-old moderately underweight children in rural Malawi ." The Journal of Nutrition 140 , no. 11 (2010) : 2008-2013
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
LaGrone, L. N., Trehan, I., Meuli, G. J., Wang, R. J., Thakwalakwa, C., Maleta, K., Manary, M. J.. "A novel fortified blended flour, corn-soy blend "plus-plus," is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children ." The American Journal of Clinical Nutrition 95 , no. 1 (2012) : 212-9
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Batra, P., Schlossman, N., Balan, I., Pruzensky, W., Balan, A., Brown, C., Gamache, M. G., Schleicher, M. M., Braima de Sa, A., Saltzman, E., Wood, L., Roberts, S. B.. "A randomized controlled trial offering higher- compared with lower-dairy second meals daily in preschools in Guinea-Bissau demonstrates an attendance-dependent increase in weight gain for both meal types and an increase in mid-upper arm circumference ." The Journal of Nutrition 146 , no. 1 (2015) : 124-132
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted
  • MAM
Mangani, C., Manary, M., Alho, L., Ashorn, P.. "A single-centre, randomized, single-blind, parallel group clinical trial in rural Malawi, testing the growth promoting effect of long-term complementary feeding of infants with a high-energy, micronutrient fortified spread ." FANTA Project (2012)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • MAM
Langlois, B., Rogers, B.. "A tale of two measures: Self-report and lab-assessed values in amount of oil Added to CSB porridge prepared by caregivers of children with moderate acute malnutrition in Southern Malawi ." The FASEB Journal 30 , no. 1 (2016)
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
Research Gaps
  • Use
Nutritional Problems being Studied
  • MAM
Iuel-Brockdorf, A., Dræbelc, T. A., Fabiansenb, C., Cichon, B., Brix Christensen, V., Yameogob, C., Ritz, C., Frahm Olsen, M., Friis, H.. "Acceptability of new formulations of corn-soy blends and lipid-based nutrient supplements in Province du Passoré, Burkina Faso ." Appetite (2015)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Composition
Nutritional Problems being Studied
  • MAM
Phuka, J., Ashorn, U., Ashorn, P., Zeilani, M., Cheung, Y. B., Dewey, K. G., Manary, M., Maleta, K.. "Acceptability of three novel lipid-based nutrient supplements among Malawian infants and their caregivers ." Maternal & Child Nutrition 7 , no. 4 (2011) : 368-377
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Composition
  • Innovation
Nutritional Problems being Studied
  • MAM
Hess, S. Y., Bado, L., Aaron, G. J., Ouédraogo, J. B., Zeilani, M., Brown, K. H.. "Acceptability of zinc-fortified, lipid-based nutrient supplements (LNS) prepared for young children in Burkina Faso ." Maternal & Child Nutrition 7 , no. 4 (2011) : 357-367
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • MAM
Ruel, M. T., Menon, P., Habicht, J., Loechl, C., Bergeron, G., Pelto, G., Arimond, M., Maluccio, J., Michaud, L., Hankebo, B.. "Age-based preventive targeting of food assistance and behaviour change and communication for reduction of childhood undernutrition in Haiti: a cluster randomised trial ." The Lancet 371 , no. 9612 (2008) : 588-595
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • MAM
Thakwalakwa, C. M., Ashorn, P., Jawati, M., Phuka, J. C., Cheung, Y. B., Maleta, K. M.. "An effectiveness trial showed lipid-based nutrient supplementation but not corn-soya blend offered a modest benefit in weight gain among 6- to 18-month-old underweight children in rural Malawi ." Public Health Nutrition 15 , no. 9 (2012) : 1755-62
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Chang, C. Y., Trehan, I., Wang, R. J., Thakwalakwa, C., Maleta, K., Deitchler, M., Manary, M. J.. "Children successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery ." The Journal of Nutrition 143 , no. 2 (2013) : 215-220
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Portillo-Reyes, V., Pérez-García, M., Loya-Méndez, Y., Puente, A. E.. "Clinical significance of neuropsychological improvement after supplementation with omega-3 in 8–12 years old malnourished Mexican children: A randomized, double-blind, placebo and treatment clinical trial ." Research in Developmental Disabilities 35 , no. 4 (2014) : 861-870
Study Interventions
  • Other
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Manary, M., Chang, C.. "Comparing milk-fortified corn-soy blend (CSB++), soy ready-to-use supplementary food (RUSF), and soy/whey RUSF (Supplementary Plumpy®) in the treatment of moderate acute malnutrition ." FANTA Project (2012)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
Nutritional Problems being Studied
  • MAM
Marron, B., Green, J., Jayson, L., Suri, D., Marcus, S., Boiteau, J., Manary, M., Webb, P., Rogers, B.. "Comparison of four different supplementary foods in the treatment of moderate acute malnutrition (MAM) in children under five in Sierra Leone ." The FASEB Journal 29 , no. 1 (2015)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Langendorf, C., Roederer, T., de Pee, S., Brown, D., Doyon, S., Mamaty, A., Touré, L. W., Manzo, M. L., Grais, R. F.. "Preventing acute malnutrition among young children in crises: A prospective intervention study in Niger ." PLOS Medicine (2012)
Study Interventions
  • Animal-source protein
  • Cash transfer
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
  • MAM
Omollo, S. A.. "Effect of improved complementary foods on lean body mass, essential fatty acids, and gross motor development of Kenyan infants ." University of Nairobi Institute of Tropical and Infectious Diseases (2014)
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • MAM
Prudhon, C., Langendorf, C., Roederer, T., Doyon, S., Mamaty, A., Woi-Messe, L., Manzo, M. L., de Pee, S., Grais, R. F.. "Effect of ready-to-use foods for preventing child undernutrition in Niger: analysis of a prospective intervention study over 15 months of follow-up ." Maternal & Child Nutrition 13 , no. 1 (2016)
Study Interventions
  • Cash transfer
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • SAM
  • MAM
van der Kam, S., Roll, S., Swarthout, T., Edyegu-Otelu, G., Matsumoto, A., Kasujja, F. X., Casademont, C., Shanks, L., Salse-Ubach, N.. "Effect of short-term supplementation with ready-to-use therapeutic food or micronutrients for children after illness for prevention of malnutrition: a randomised controlled trial in Uganda ." PLoS Medicine 13 , no. 2 (2016) : e1001951
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Amegovu, Andrew Kiri, Ochola, Sophie, Ogwok, Patrick, Yiga, Peter, Musalima, Juliet, Juliana, Mandha. "Efficacy of sorghum peanut blend and corn soy blend plus in the treatment of moderate acute malnutrition in children aged 6–59 months in Karamoja, Uganda: a cluster randomized trial ." Nutrition & Dietary Supplements 6 (2014) : 75-84
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Innovation
Nutritional Problems being Studied
  • MAM
Iuel-Brockdorf, A. S., Draebel, T. A., Ritz, C., Fabiansen, C., Cichon, B., Brix Christensen, V., Yameogo, C., Oummani, R., Briend, A., Michaelsen, K. F., Ashorn, P., Filteau, S., Friis, H.. "Evaluation of the acceptability of improved supplementary foods for the treatment of moderate acute malnutrition in Burkina Faso using a mixed method approach ." Appetite 99 (2016) : 34-45
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Trehan, I., Banerjee, S., Murray, E.. "Extending supplementary feeding for children younger than 5 years with moderate acute malnutrition leads to lower relapse rates ." Journal of Pediatric Gastroenterology & Nutrition 60 , no. 4 (2015) : 544-549
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Flax, V. L., Phuka, J., Cheung, Y. B., Ashorn, U., Maleta, K., Ashorn, P.. "Feeding patterns and behaviors during home supplementation of underweight Malawian children with lipid-based nutrient supplements or corn-soy blend ." Appetite 54 , no. 3 (2010) : 504-11
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Use
Nutritional Problems being Studied
  • MAM
Karakochuk, C. D., van den Briel, T., Stephens, D., Zlotkin, S.. "Food sharing practices in households receiving supplemental foods for the treatment of moderate acute malnutrition in Ethiopian children ." Journal of Hunger & Environmental Nutrition 10 , no. 3 (2015) : 343-355
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Use
Nutritional Problems being Studied
  • MAM
Tripp, K., Clayton, H., Nanema, A., Mujinga, W., Kupka, R., Sandalinas, F., Nanama, S., Jungjohann, S., Chatelier, M. L., Palma, C.. "Formative assessment to design the packaging of a lipid-based nutrient supplement for a home fortification program to improve the nutritional status of young children in the Democratic Republic of Congo (DRC) ." (2013)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • SAM
  • MAM