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This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 98 Results
Thakwalakwa, C., Ashorn, P., Phuka, J., Cheung, Y. B., Briend, A., Puumalainen, T., Maleta, K.. "A lipid-based nutrient supplement but not corn-soy blend modestly increases weight gain among 6-to 18-month-old moderately underweight children in rural Malawi ." The Journal of Nutrition 140 , no. 11 (2010) : 2008-2013
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
LaGrone, L. N., Trehan, I., Meuli, G. J., Wang, R. J., Thakwalakwa, C., Maleta, K., Manary, M. J.. "A novel fortified blended flour, corn-soy blend "plus-plus," is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children ." The American Journal of Clinical Nutrition 95 , no. 1 (2012) : 212-9
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Mangani, C., Manary, M., Alho, L., Ashorn, P.. "A single-centre, randomized, single-blind, parallel group clinical trial in rural Malawi, testing the growth promoting effect of long-term complementary feeding of infants with a high-energy, micronutrient fortified spread ." FANTA Project (2012)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • MAM
Langlois, B., Rogers, B.. "A tale of two measures: Self-report and lab-assessed values in amount of oil Added to CSB porridge prepared by caregivers of children with moderate acute malnutrition in Southern Malawi ." The FASEB Journal 30 , no. 1 (2016)
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
Research Gaps
  • Use
Nutritional Problems being Studied
  • MAM
Iuel-Brockdorf, A., Dræbelc, T. A., Fabiansenb, C., Cichon, B., Brix Christensen, V., Yameogob, C., Ritz, C., Frahm Olsen, M., Friis, H.. "Acceptability of new formulations of corn-soy blends and lipid-based nutrient supplements in Province du Passoré, Burkina Faso ." Appetite (2015)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Composition
Nutritional Problems being Studied
  • MAM
Ruel, M. T., Menon, P., Habicht, J., Loechl, C., Bergeron, G., Pelto, G., Arimond, M., Maluccio, J., Michaud, L., Hankebo, B.. "Age-based preventive targeting of food assistance and behaviour change and communication for reduction of childhood undernutrition in Haiti: a cluster randomised trial ." The Lancet 371 , no. 9612 (2008) : 588-595
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • MAM
Thakwalakwa, C. M., Ashorn, P., Jawati, M., Phuka, J. C., Cheung, Y. B., Maleta, K. M.. "An effectiveness trial showed lipid-based nutrient supplementation but not corn-soya blend offered a modest benefit in weight gain among 6- to 18-month-old underweight children in rural Malawi ." Public Health Nutrition 15 , no. 9 (2012) : 1755-62
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Bahwere, P., Balaluka, B., Wells, J. C., Mbiribindi, C. N., Sadler, K., Akomo, P., Dramaix-Wilmet, M., Collins, S.. "Cereals and pulse-based ready-to-use therapeutic food as an alternative to the standard milk- and peanut paste-based formulation for treating severe acute malnutrition: a noninferiority, individually randomized controlled efficacy clinical trial ." The American Journal of Clinical Nutrition 103 , no. 4 (2016) : 1145-1161
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Efficacy
Nutritional Problems being Studied
  • SAM
Chang, C. Y., Trehan, I., Wang, R. J., Thakwalakwa, C., Maleta, K., Deitchler, M., Manary, M. J.. "Children successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery ." The Journal of Nutrition 143 , no. 2 (2013) : 215-220
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Manary, M., Chang, C.. "Comparing milk-fortified corn-soy blend (CSB++), soy ready-to-use supplementary food (RUSF), and soy/whey RUSF (Supplementary Plumpy®) in the treatment of moderate acute malnutrition ." FANTA Project (2012)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
Nutritional Problems being Studied
  • MAM
Marron, B., Green, J., Jayson, L., Suri, D., Marcus, S., Boiteau, J., Manary, M., Webb, P., Rogers, B.. "Comparison of four different supplementary foods in the treatment of moderate acute malnutrition (MAM) in children under five in Sierra Leone ." The FASEB Journal 29 , no. 1 (2015)
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Langendorf, C., Roederer, T., de Pee, S., Brown, D., Doyon, S., Mamaty, A., Touré, L. W., Manzo, M. L., Grais, R. F.. "Preventing acute malnutrition among young children in crises: A prospective intervention study in Niger ." PLOS Medicine (2012)
Study Interventions
  • Animal-source protein
  • Cash transfer
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
  • MAM
Phuka, J. C., Gladstone, M., Maleta, K., Thakwalakwa, C., Cheung, Y. B., Briend, A., Manary, M. J., Ashorn, P.. "Developmental outcomes among 18‐month‐old Malawians after a year of complementary feeding with lipid‐based nutrient supplements or corn‐soy flour ." Maternal & Child Nutrition 8 , no. 2 (2012) : 239-248
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Ruel, M. T., Menon, P., Loechl, C., Pelto, G.. "Donated fortified cereal blends improve the nutrient density of traditional complementary foods in Haiti, but iron and zinc gaps remain for infants ." Food and Nutrition Bulletin 25 , no. 4 (2004) : 361-376
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted
Christian, P., Shaikh, S., Shamim, A. A., Mehra, S., Wu, L., Merrill, R. D., Klemm, R., Schulze, K., Pee, S., Ahmed, T.. "Effect of fortified complementary food supplementation on child growth in rural Bangladesh: A cluster-randomized trial ." The FASEB Journal 29 , no. 1 Supplement (2015) : 120.5
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Omollo, S. A.. "Effect of improved complementary foods on lean body mass, essential fatty acids, and gross motor development of Kenyan infants ." University of Nairobi Institute of Tropical and Infectious Diseases (2014)
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • MAM
Skau, J. K. H., Touch, B., Chhoun, C., Chea, M., Unni, U. S., Makurat, J., Filteau, S., Wieringa, F. T., Dijkhuizen, M. A., Ritz, C., Wells, J. C., Berger, J., Friis, H., Michaelsen, K. F., Roos, N.. "Effects of animal source food and micronutrient fortification in complementary food products on body composition, iron status, and linear growth: A randomized trial in Cambodia ." The American Journal of Clinical Nutrition 101 , no. 4 (2015) : 742-751
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
Hossain, M. I., Nahar, B., Hamadani, J. D., Ahmed, T., Brown, K. H.. "Effects of community-based follow-up care in managing severely underweight children ." Journal of Pediatric Gastroenterology and Nutrition 53 , no. 3 (2011) : 310-319
Study Interventions
  • Fortified blended foods (FBF)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
Amegovu, Andrew Kiri, Ochola, Sophie, Ogwok, Patrick, Yiga, Peter, Musalima, Juliet, Juliana, Mandha. "Efficacy of sorghum peanut blend and corn soy blend plus in the treatment of moderate acute malnutrition in children aged 6–59 months in Karamoja, Uganda: a cluster randomized trial ." Nutrition & Dietary Supplements 6 (2014) : 75-84
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Innovation
Nutritional Problems being Studied
  • MAM
Iuel-Brockdorf, A. S., Draebel, T. A., Ritz, C., Fabiansen, C., Cichon, B., Brix Christensen, V., Yameogo, C., Oummani, R., Briend, A., Michaelsen, K. F., Ashorn, P., Filteau, S., Friis, H.. "Evaluation of the acceptability of improved supplementary foods for the treatment of moderate acute malnutrition in Burkina Faso using a mixed method approach ." Appetite 99 (2016) : 34-45
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Trehan, I., Banerjee, S., Murray, E.. "Extending supplementary feeding for children younger than 5 years with moderate acute malnutrition leads to lower relapse rates ." Journal of Pediatric Gastroenterology & Nutrition 60 , no. 4 (2015) : 544-549
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Flax, V. L., Phuka, J., Cheung, Y. B., Ashorn, U., Maleta, K., Ashorn, P.. "Feeding patterns and behaviors during home supplementation of underweight Malawian children with lipid-based nutrient supplements or corn-soy blend ." Appetite 54 , no. 3 (2010) : 504-11
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Use
Nutritional Problems being Studied
  • MAM
Karakochuk, C. D., van den Briel, T., Stephens, D., Zlotkin, S.. "Food sharing practices in households receiving supplemental foods for the treatment of moderate acute malnutrition in Ethiopian children ." Journal of Hunger & Environmental Nutrition 10 , no. 3 (2015) : 343-355
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Use
Nutritional Problems being Studied
  • MAM
Cheung, Y. B., Xu, Y., Mangani, C., Fan, Y. M., Dewey, K. G., Salminen, S. J., Maleta, K., Ashorn, P.. "Gut microbiota in Malawian infants in a nutritional supplementation trial ." Tropical Medicine & International Health 21 , no. 2 (2015) : 283-90
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
  • Plant-source protein
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • MAM
Wang, R. J., Trehan, I., LaGrone, L. N., Weisz, A. J., Thakwalakwa, C. M., Maleta, K. M., Manary, M. J.. "Investigation of food acceptability and feeding practices for lipid nutrient supplements and blended flours used to treat moderate malnutrition ." Journal of Nutrition Education and Behavior 45 , no. 3 (2013) : 258-263
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • MAM