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This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 50 Results
Ramírez-Luzuriaga, M. J., Unar-Munguía, M., Rodríguez-Ramírez, S., Rivera, J. A., González de Cosío, T.. "A food transfer program without a formal education component modifies complementary feeding practices in poor rural Mexican communities ." The Journal of Nutrition 146 , no. 1 (2016) : 107-13
Study Interventions
  • Animal-source protein
  • Behavior change communication (BCC)
  • Cash transfer
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
LaGrone, L. N., Trehan, I., Meuli, G. J., Wang, R. J., Thakwalakwa, C., Maleta, K., Manary, M. J.. "A novel fortified blended flour, corn-soy blend "plus-plus," is not inferior to lipid-based ready-to-use supplementary foods for the treatment of moderate acute malnutrition in Malawian children ." The American Journal of Clinical Nutrition 95 , no. 1 (2012) : 212-9
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Batra, P., Schlossman, N., Balan, I., Pruzensky, W., Balan, A., Brown, C., Gamache, M. G., Schleicher, M. M., Braima de Sa, A., Saltzman, E., Wood, L., Roberts, S. B.. "A randomized controlled trial offering higher- compared with lower-dairy second meals daily in preschools in Guinea-Bissau demonstrates an attendance-dependent increase in weight gain for both meal types and an increase in mid-upper arm circumference ." The Journal of Nutrition 146 , no. 1 (2015) : 124-132
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted
  • MAM
Oakley, E., Reinking, J., Sandige, H., Trehan, I., Kennedy, G., Maleta, K., Manary, M.. "A ready-to-use therapeutic food containing 10% milk is less effective than one with 25% milk in the treatment of severely malnourished children ." The Journal of Nutrition 140 , no. 12 (2010) : 2248-2252
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Efficacy
Nutritional Problems being Studied
  • SAM
Mangani, C., Manary, M., Alho, L., Ashorn, P.. "A single-centre, randomized, single-blind, parallel group clinical trial in rural Malawi, testing the growth promoting effect of long-term complementary feeding of infants with a high-energy, micronutrient fortified spread ." FANTA Project (2012)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • MAM
Iuel-Brockdorf, A., Dræbelc, T. A., Fabiansenb, C., Cichon, B., Brix Christensen, V., Yameogob, C., Ritz, C., Frahm Olsen, M., Friis, H.. "Acceptability of new formulations of corn-soy blends and lipid-based nutrient supplements in Province du Passoré, Burkina Faso ." Appetite (2015)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Composition
Nutritional Problems being Studied
  • MAM
Rothman, M., Berti, C., Smuts, C. M., Faber, M., Covic, N.. "Acceptability of novel small-quantity lipid-based nutrient supplements for complementary feeding in a peri-urban South African community ." Food and Nutrition Bulletin 36 , no. 4 (2015) : 455-466
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • Stunted
Phuka, J., Ashorn, U., Ashorn, P., Zeilani, M., Cheung, Y. B., Dewey, K. G., Manary, M., Maleta, K.. "Acceptability of three novel lipid-based nutrient supplements among Malawian infants and their caregivers ." Maternal & Child Nutrition 7 , no. 4 (2011) : 368-377
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Composition
  • Innovation
Nutritional Problems being Studied
  • MAM
Hess, S. Y., Bado, L., Aaron, G. J., Ouédraogo, J. B., Zeilani, M., Brown, K. H.. "Acceptability of zinc-fortified, lipid-based nutrient supplements (LNS) prepared for young children in Burkina Faso ." Maternal & Child Nutrition 7 , no. 4 (2011) : 357-367
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
Nutritional Problems being Studied
  • MAM
Thakwalakwa, C. M., Ashorn, P., Jawati, M., Phuka, J. C., Cheung, Y. B., Maleta, K. M.. "An effectiveness trial showed lipid-based nutrient supplementation but not corn-soya blend offered a modest benefit in weight gain among 6- to 18-month-old underweight children in rural Malawi ." Public Health Nutrition 15 , no. 9 (2012) : 1755-62
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Steenkamp, L., Nomvete, A., Venter, D.. "Catch-up growth in children with severe acute malnutrition: comparison of two therapeutic feeding approaches at a district hospital, South Africa ." Africa Journal of Nursing and Midwifery 17 , no. 2 (2016)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Bahwere, P., Balaluka, B., Wells, J. C., Mbiribindi, C. N., Sadler, K., Akomo, P., Dramaix-Wilmet, M., Collins, S.. "Cereals and pulse-based ready-to-use therapeutic food as an alternative to the standard milk- and peanut paste-based formulation for treating severe acute malnutrition: a noninferiority, individually randomized controlled efficacy clinical trial ." The American Journal of Clinical Nutrition 103 , no. 4 (2016) : 1145-1161
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Efficacy
Nutritional Problems being Studied
  • SAM
Namusoke, H., Hother, A., Rytter, M. J., Kæstel, P., Babirekere-Iriso, E., Fabiansen, C., Girma, T., Ritz, C., Michaelsen, K., Briend, A., Friis, H.. "Changes in plasma phosphate during in-patient treatment of children with severe acute malnutrition: an observational study in Uganda ." The American Journal of Clinical Nutrition (2016)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Babirekere-Iriso, E., Mortensen, C. G., Mupere, E., Rytter, M. J., Namusoke, H., Michaelsen, K. F., Briend, A., Stark, K. D., Friis, H., Lauritzen, L.. "Changes in whole-blood PUFA and their predictors during recovery from severe acute malnutrition ." The British Journal of Nutrition 115 , no. 10 (2016) : 1730-9
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Chang, C. Y., Trehan, I., Wang, R. J., Thakwalakwa, C., Maleta, K., Deitchler, M., Manary, M. J.. "Children successfully treated for moderate acute malnutrition remain at risk for malnutrition and death in the subsequent year after recovery ." The Journal of Nutrition 143 , no. 2 (2013) : 215-220
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Mehta, B., Imran, A.. "Clinical and anthropometric profile of severe acute malnourished children on therapeutic intervention with WHO/UNICEF recommended therapeutic food ." International Journal of Science and Research 4 , no. 4 (2014) : 268-273
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Manary, M., Chang, C.. "Comparing milk-fortified corn-soy blend (CSB++), soy ready-to-use supplementary food (RUSF), and soy/whey RUSF (Supplementary Plumpy®) in the treatment of moderate acute malnutrition ." FANTA Project (2012)
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
Nutritional Problems being Studied
  • MAM
Langendorf, C., Roederer, T., de Pee, S., Brown, D., Doyon, S., Mamaty, A., Touré, L. W., Manzo, M. L., Grais, R. F.. "Preventing acute malnutrition among young children in crises: A prospective intervention study in Niger ." PLOS Medicine (2012)
Study Interventions
  • Animal-source protein
  • Cash transfer
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • SAM
  • MAM
Diop, E. H. I., Dossou, N. I., Ndour, M. M., Briend, A., Wade, S.. "Comparison of the efficacy of a solid ready-to-use food and a liquid, milk-based diet for the rehabilitation of severely malnourished children: A randomized trial ." American Journal of Clinical Nutrition 78 , no. 2 (2003) : 302-307
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
  • Other
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Lebenthal, Y., Yackobovitch-Gavan, M., Lazar, L., Shalitin, S., Tenenbaum, A., Shamir, R., Phillip, M.. "Effect of a nutritional supplement on growth in short and lean prepubertal children: a prospective, randomized, double-blind, placebo-controlled study ." The Journal of Pediatrics 165 , no. 6 (2014) : 1190-1193.e1
Study Interventions
  • Animal-source protein
  • Other
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
Bahwere, P., Banda, T., Sadler, K., Nyirenda, G., Owino, V., Shaba, B., Dibari, F., Collins, S.. "Effectiveness of milk whey protein-based ready-to-use therapeutic food in treatment of severe acute malnutrition in Malawian under-5 children: a randomised, double-blind, controlled non-inferiority clinical trial ." Maternal & Child Nutrition 10 , no. 3 (2014) : 436-451
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Composition
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Iuel-Brockdorf, A. S., Draebel, T. A., Ritz, C., Fabiansen, C., Cichon, B., Brix Christensen, V., Yameogo, C., Oummani, R., Briend, A., Michaelsen, K. F., Ashorn, P., Filteau, S., Friis, H.. "Evaluation of the acceptability of improved supplementary foods for the treatment of moderate acute malnutrition in Burkina Faso using a mixed method approach ." Appetite 99 (2016) : 34-45
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Trehan, I., Banerjee, S., Murray, E.. "Extending supplementary feeding for children younger than 5 years with moderate acute malnutrition leads to lower relapse rates ." Journal of Pediatric Gastroenterology & Nutrition 60 , no. 4 (2015) : 544-549
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Cheung, Y. B., Xu, Y., Mangani, C., Fan, Y. M., Dewey, K. G., Salminen, S. J., Maleta, K., Ashorn, P.. "Gut microbiota in Malawian infants in a nutritional supplementation trial ." Tropical Medicine & International Health 21 , no. 2 (2015) : 283-90
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
  • Plant-source protein
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • MAM
Nguefack, F., Adjahoung, C. A., Keugoung, B., Kamgaing, N., Dongmo, R.. "Hospital management of severe acute malnutrition in children with F-75 and F-100 alternative local preparations: results and challenges ." The Pan African Medical Journal 21 (2015) : 329
Study Interventions
  • Animal-source protein
  • Locally produced
Research Gaps
  • Composition
  • Efficacy
  • Innovation
Nutritional Problems being Studied
  • SAM