Published Studies

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This page includes publications from individual clinical trials testing food aid products, and reports and evaluations from programs using food aid products. These resources are tagged according to country, nutritional problem studied, intervention used, study type, year, and author. If relevant to more than one category, the document appears in both categories. New resources are added regularly according to search criteria and standards developed by REFINE.

Do you know of a recently published study or trial that isn’t included here? Email us at REFINEnutrition@gmail.com!


Displaying 1 - 25 of 44 Results
Ramírez-Luzuriaga, M. J., Unar-Munguía, M., Rodríguez-Ramírez, S., Rivera, J. A., González de Cosío, T.. "A food transfer program without a formal education component modifies complementary feeding practices in poor rural Mexican communities ." The Journal of Nutrition 146 , no. 1 (2016) : 107-13
Study Interventions
  • Animal-source protein
  • Behavior change communication (BCC)
  • Cash transfer
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
Langlois, B., Rogers, B.. "A tale of two measures: Self-report and lab-assessed values in amount of oil Added to CSB porridge prepared by caregivers of children with moderate acute malnutrition in Southern Malawi ." The FASEB Journal 30 , no. 1 (2016)
Study Interventions
  • Behavior change communication (BCC)
  • Fortified blended foods (FBF)
Research Gaps
  • Use
Nutritional Problems being Studied
  • MAM
Steenkamp, L., Nomvete, A., Venter, D.. "Catch-up growth in children with severe acute malnutrition: comparison of two therapeutic feeding approaches at a district hospital, South Africa ." Africa Journal of Nursing and Midwifery 17 , no. 2 (2016)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Bahwere, P., Balaluka, B., Wells, J. C., Mbiribindi, C. N., Sadler, K., Akomo, P., Dramaix-Wilmet, M., Collins, S.. "Cereals and pulse-based ready-to-use therapeutic food as an alternative to the standard milk- and peanut paste-based formulation for treating severe acute malnutrition: a noninferiority, individually randomized controlled efficacy clinical trial ." The American Journal of Clinical Nutrition 103 , no. 4 (2016) : 1145-1161
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Locally produced
  • Plant-source protein
Research Gaps
  • Composition
  • Efficacy
Nutritional Problems being Studied
  • SAM
Tadesse, E., Ekström, E., Berhane, Y.. "Challenges in implementing the integrated community-based outpatient therapeutic program for severely malnourished children in rural Southern Ethiopia ." Nutrients 8 , no. 5 (2016) : 251
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • SAM
Namusoke, H., Hother, A., Rytter, M. J., Kæstel, P., Babirekere-Iriso, E., Fabiansen, C., Girma, T., Ritz, C., Michaelsen, K., Briend, A., Friis, H.. "Changes in plasma phosphate during in-patient treatment of children with severe acute malnutrition: an observational study in Uganda ." The American Journal of Clinical Nutrition (2016)
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Babirekere-Iriso, E., Mortensen, C. G., Mupere, E., Rytter, M. J., Namusoke, H., Michaelsen, K. F., Briend, A., Stark, K. D., Friis, H., Lauritzen, L.. "Changes in whole-blood PUFA and their predictors during recovery from severe acute malnutrition ." The British Journal of Nutrition 115 , no. 10 (2016) : 1730-9
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Efficacy
Nutritional Problems being Studied
  • SAM
Prudhon, C., Langendorf, C., Roederer, T., Doyon, S., Mamaty, A., Woi-Messe, L., Manzo, M. L., de Pee, S., Grais, R. F.. "Effect of ready-to-use foods for preventing child undernutrition in Niger: analysis of a prospective intervention study over 15 months of follow-up ." Maternal & Child Nutrition 13 , no. 1 (2016)
Study Interventions
  • Cash transfer
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • SAM
  • MAM
van der Kam, S., Roll, S., Swarthout, T., Edyegu-Otelu, G., Matsumoto, A., Kasujja, F. X., Casademont, C., Shanks, L., Salse-Ubach, N.. "Effect of short-term supplementation with ready-to-use therapeutic food or micronutrients for children after illness for prevention of malnutrition: a randomised controlled trial in Uganda ." PLoS Medicine 13 , no. 2 (2016) : e1001951
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Prado, E. L., Abbeddou, S., Yakes Jimenez, E., Somé, J. W., Dewey, K. G., Brown, K. H., Hess, S. Y.. "Effects of an intervention on infant growth and development: evidence for different mechanisms at work ." Maternal & Child Nutrition (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
Prado, E. L., Maleta, K., Ashorn, P., Ashorn, U., Vosti, S. A., Sadalaki, J., Dewey, K. G.. "Effects of maternal and child lipid-based nutrient supplements on infant development: a randomized trial in Malawi ." American Journal of Clinical Nutrition 103 , no. 3 (2016) : 784-793
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
Prado, E. L., Adu-Afarwuah, S., Lartey, A., Ocansey, M., Ashorn, P., Vosti, S. A., Dewey, K. G.. "Effects of pre- and post-natal lipid-based nutrient supplements on infant development in a randomized trial in Ghana ." Early Human Development 99 (2016) : 43-51
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Iuel-Brockdorf, A. S., Draebel, T. A., Ritz, C., Fabiansen, C., Cichon, B., Brix Christensen, V., Yameogo, C., Oummani, R., Briend, A., Michaelsen, K. F., Ashorn, P., Filteau, S., Friis, H.. "Evaluation of the acceptability of improved supplementary foods for the treatment of moderate acute malnutrition in Burkina Faso using a mixed method approach ." Appetite 99 (2016) : 34-45
Study Interventions
  • Animal-source protein
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Stobaugh, H. C., Ryan, K. N., Kennedy, J. A., Grise, J. B., Crocker, A. H., Thakwalakwa, C., Litkowski, P. E., Maleta, K. M., Manary, M. J., Trehan, I.. "Including whey protein and whey permeate in ready-to-use supplementary food improves recovery rates in children with moderate acute malnutrition: a randomized, double-blind clinical trial ." American Journal of Clinical Nutrition 103 , no. 3 (2016) : 926-933
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Composition
Nutritional Problems being Studied
  • MAM
Mridha, M. K., Matias, S. L., Chaparro, C. M., Paul, R. R., Hussain, S., Vosti, S. A., Harding, K. L., Cummins, J. R., Day, L. T., Saha, S. L., Peerson, J. M., Dewey, K. G.. "Lipid-based nutrient supplements for pregnant women reduce newborn stunting in a cluster-randomized controlled effectiveness trial in Bangladesh ." The American of Clinical Nutrition 103 , no. 1 (2016) : 236-49
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Hemsworth, J., Kumwenda, C., Arimond, M., Maleta, K., Phuka, J., Rehman, A. M., Vosti, S. A., Ashorn, U., Filteau, S., Dewey, K. G., Ashorn, P., Ferguson, E. L.. "Lipid-based nutrient supplements increase energy and macronutrient intakes from complementary food among Malawian infants ." The Journal of Nutrition 146 , no. 2 (2016) : 326-34
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • Stunted
Medoua, G. N., Ntsama, P. M., Ndzana, A. C., Essa'a, V. J., Tsafack, J. J., Dimodi, H. T.. "Recovery rate of children with moderate acute malnutrition treated with ready-to-use supplementary food (RUSF) or improved corn–soya blend (CSB+): a randomized controlled trial ." Public Health Nutrition 19 , no. 2 (2016) : 363-370
Study Interventions
  • Fortified blended foods (FBF)
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
  • Use
Nutritional Problems being Studied
  • MAM
Isanaka, S., Langendorf, C., Berthé, F., Gnegne, S., Li, N., Ousmane, N., Harouna, S., Hassane, H., Schaefer, M., Adehossi, E., Grais, R. F.. "Routine amoxicillin for uncomplicated severe acute malnutrition in children ." The New England Journal of Medicine 374 (2016) : 444-453
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Other
Research Gaps
  • Innovation
Nutritional Problems being Studied
  • SAM
Burza, S., Mahajan, R., Marino, E., Sunyoto, T., Shandilya, C., Tabrez, M., Kumar, K., Jha, A, Mathew, P., Salse, N., Casademont, C., Mishra, N. K.. "Seasonal effect and long-term nutritional status following exit from a Community-Based Management of Severe Acute Malnutrition program in Bihar, India ." European Journal of Clinical Nutrition 70 , no. 4 (2016) : 437-44
Study Interventions
  • Animal-source protein
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • SAM
Adu-Afarwuah, S., Lartey, A., Okronipa, H., Ashorn, P., Peerson, J. M., Arimond, M., Ashorn, U., Zeilani, M., Vosti, S., Dewey, K. G.. "Small-quantity, lipid-based nutrient supplements provided to women during pregnancy and 6 mo postpartum and to their infants from 6 mo of age increase the mean attained length of 18-mo-old children in semi-urban Ghana: a randomized controlled trial ." The American Journal of Clinical Nutrition 104 , no. 3 (2016) : 797-808
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Micronutrient powders (MNP)
Research Gaps
  • Composition
  • Effectiveness
  • Innovation
Nutritional Problems being Studied
  • Stunted
  • GAM
Cames, C., Varloteaux, M., Have, N. N., Diom, A. B.,, Msellati, P., Mbaye, N., Mbodji, H., Sy Signate, H., Diack, A., ANRS 12279 MAGGSEN Cohort Study. "Acceptability of outpatient ready-to-use food-based protocols in HIV-infected Senegalese children and adolescents within the MAGGSEN cohort study ." Food and Nutrition Bulletin (2016)
Study Interventions
  • Lipid-based nutrient supplements (LNS)
  • Plant-source protein
Research Gaps
  • Acceptability
  • Effectiveness
Nutritional Problems being Studied
  • SAM
  • MAM
Choudhury, N., Bromage, S., Alam, M. A., Shamsir Ahmed, A. M., Munirul Islam, M., Iqbal Hossain, M., Mahfuz, M., Mondal, D., Ahmed, T.. "Intervention study shows suboptimal growth among children receiving a food supplement for five months in a slum in Bangladesh ." Acta Paediatrica 105 , no. 10 (2016) : e464-e473
Study Interventions
  • Fortified blended foods (FBF)
  • Locally produced
  • Micronutrient powders (MNP)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • MAM
Klevor, M. K., Adu-Afarwuah, S., Ashorn, P., Arimond, M., Dewey, K. G., Lartey, A., Maleta, K., Phiri, N., Pyykko, J., Zeilani, M., Ashorn, U.. "A mixed method study exploring adherence to and acceptability of small quantity lipid-based nutrient supplements (SQ-LNS) among pregnant and lactating women in Ghana and Malawi ." BMC Pregnancy and Childbirth 16 , no. 1 (2016) : 253
Study Interventions
  • Lipid-based nutrient supplements (LNS)
Research Gaps
  • Acceptability
  • Use
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Leroy, J. L., Olney, D. K., Ruel, M. T.. "Tubaramure, a food-assisted integrated health and nutrition program in Burundi, increases maternal and child hemoglobin concentrations and reduces anemia: A theory-based cluster-randomized controlled intervention trial  ." Journal of Nutrition 146 , no. 8 (2016) : 1601-1608
Study Interventions
  • Fortified blended foods (FBF)
Research Gaps
  • Effectiveness
Nutritional Problems being Studied
  • Stunted
  • Pregnant & Lactating Women
Leyvraz, M., Rohner, F., Konan, A. G., Esso, L. J. C. E., Woodruff, B. A., Norte, A., Adiko, A. F., Bonfoh, B., Aaron, G. J.. "High awareness but low coverage of a locally produced fortified complementary food in Abidjan, Côte d’Ivoire: Findings from a cross-sectional survey ." PLOS ONE 11 , no. 11 (2016) : e0166295
Study Interventions
  • Locally produced
Research Gaps
  • Innovation
  • Use
Nutritional Problems being Studied
  • Stunted